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Journal Abstract Search

444 related items for PubMed ID: 20159607

  • 1. MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele.
    Thiel AT, Blessington P, Zou T, Feather D, Wu X, Yan J, Zhang H, Liu Z, Ernst P, Koretzky GA, Hua X.
    Cancer Cell; 2010 Feb 17; 17(2):148-59. PubMed ID: 20159607
    [Abstract] [Full Text] [Related]

  • 2. CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis.
    Tan J, Jones M, Koseki H, Nakayama M, Muntean AG, Maillard I, Hess JL.
    Cancer Cell; 2011 Nov 15; 20(5):563-75. PubMed ID: 22094252
    [Abstract] [Full Text] [Related]

  • 3. The trithorax protein partner menin acts in tandem with EZH2 to suppress C/EBPα and differentiation in MLL-AF9 leukemia.
    Thiel AT, Feng Z, Pant DK, Chodosh LA, Hua X.
    Haematologica; 2013 Jun 15; 98(6):918-27. PubMed ID: 23349306
    [Abstract] [Full Text] [Related]

  • 4. DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.
    Nguyen AT, Taranova O, He J, Zhang Y.
    Blood; 2011 Jun 23; 117(25):6912-22. PubMed ID: 21521783
    [Abstract] [Full Text] [Related]

  • 5. An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model.
    Bergerson RJ, Collier LS, Sarver AL, Been RA, Lugthart S, Diers MD, Zuber J, Rappaport AR, Nixon MJ, Silverstein KA, Fan D, Lamblin AF, Wolff L, Kersey JH, Delwel R, Lowe SW, O'Sullivan MG, Kogan SC, Adams DJ, Largaespada DA.
    Blood; 2012 May 10; 119(19):4512-23. PubMed ID: 22427200
    [Abstract] [Full Text] [Related]

  • 6. Two decades of leukemia oncoprotein epistasis: the MLL1 paradigm for epigenetic deregulation in leukemia.
    Li BE, Ernst P.
    Exp Hematol; 2014 Dec 10; 42(12):995-1012. PubMed ID: 25264566
    [Abstract] [Full Text] [Related]

  • 7. Targeted down-regulation of MLL-AF9 with antisense oligodeoxyribonucleotide reduces the expression of the HOXA7 and -A10 genes and induces apoptosis in a human leukemia cell line, THP-1.
    Kawagoe H, Kawagoe R, Sano K.
    Leukemia; 2001 Nov 10; 15(11):1743-9. PubMed ID: 11681416
    [Abstract] [Full Text] [Related]

  • 8. Absence of the Shb gene in mixed-lineage leukemia MLL-AF9 cells increases latency in mice despite higher proliferation rates in vitro.
    Jamalpour M, Bergquist E, Welsh M.
    Exp Cell Res; 2020 Dec 15; 397(2):112368. PubMed ID: 33220260
    [Abstract] [Full Text] [Related]

  • 9. Human MLL-AF9 Overexpression Induces Aberrant Hematopoietic Expansion in Zebrafish.
    Tan J, Zhao L, Wang G, Li T, Li D, Xu Q, Chen X, Shang Z, Wang J, Zhou J.
    Biomed Res Int; 2018 Dec 15; 2018():6705842. PubMed ID: 30003105
    [Abstract] [Full Text] [Related]

  • 10. c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis.
    Jin S, Zhao H, Yi Y, Nakata Y, Kalota A, Gewirtz AM.
    J Clin Invest; 2010 Feb 15; 120(2):593-606. PubMed ID: 20093773
    [Abstract] [Full Text] [Related]

  • 11. Menin as a hub controlling mixed lineage leukemia.
    Thiel AT, Huang J, Lei M, Hua X.
    Bioessays; 2012 Sep 15; 34(9):771-80. PubMed ID: 22829075
    [Abstract] [Full Text] [Related]

  • 12. MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome.
    Wang QF, Wu G, Mi S, He F, Wu J, Dong J, Luo RT, Mattison R, Kaberlein JJ, Prabhakar S, Ji H, Thirman MJ.
    Blood; 2011 Jun 23; 117(25):6895-905. PubMed ID: 21518926
    [Abstract] [Full Text] [Related]

  • 13. Degree of recruitment of DOT1L to MLL-AF9 defines level of H3K79 Di- and tri-methylation on target genes and transformation potential.
    Kuntimaddi A, Achille NJ, Thorpe J, Lokken AA, Singh R, Hemenway CS, Adli M, Zeleznik-Le NJ, Bushweller JH.
    Cell Rep; 2015 May 05; 11(5):808-20. PubMed ID: 25921540
    [Abstract] [Full Text] [Related]

  • 14. Hoxa9 influences the phenotype but not the incidence of Mll-AF9 fusion gene leukemia.
    Kumar AR, Hudson WA, Chen W, Nishiuchi R, Yao Q, Kersey JH.
    Blood; 2004 Mar 01; 103(5):1823-8. PubMed ID: 14615372
    [Abstract] [Full Text] [Related]

  • 15. The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis.
    Yokoyama A, Somervaille TC, Smith KS, Rozenblatt-Rosen O, Meyerson M, Cleary ML.
    Cell; 2005 Oct 21; 123(2):207-18. PubMed ID: 16239140
    [Abstract] [Full Text] [Related]

  • 16. Functional specificity of CpG DNA-binding CXXC domains in mixed lineage leukemia.
    Risner LE, Kuntimaddi A, Lokken AA, Achille NJ, Birch NW, Schoenfelt K, Bushweller JH, Zeleznik-Le NJ.
    J Biol Chem; 2013 Oct 11; 288(41):29901-10. PubMed ID: 23990460
    [Abstract] [Full Text] [Related]

  • 17. Molecular mechanisms of MLL-associated leukemia.
    Yokoyama A.
    Int J Hematol; 2015 Apr 11; 101(4):352-61. PubMed ID: 25773519
    [Abstract] [Full Text] [Related]

  • 18. Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.
    Biswas D, Milne TA, Basrur V, Kim J, Elenitoba-Johnson KS, Allis CD, Roeder RG.
    Proc Natl Acad Sci U S A; 2011 Sep 20; 108(38):15751-6. PubMed ID: 21896721
    [Abstract] [Full Text] [Related]

  • 19. Bioflavonoids promote stable translocations between MLL-AF9 breakpoint cluster regions independent of normal chromosomal context: Model system to screen environmental risks.
    Bariar B, Vestal CG, Deem B, Goodenow D, Ughetta M, Engledove RW, Sahyouni M, Richardson C.
    Environ Mol Mutagen; 2019 Mar 20; 60(2):154-167. PubMed ID: 30387535
    [Abstract] [Full Text] [Related]

  • 20. Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis.
    Valerio DG, Xu H, Chen CW, Hoshii T, Eisold ME, Delaney C, Cusan M, Deshpande AJ, Huang CH, Lujambio A, Zheng YG, Zuber J, Pandita TK, Lowe SW, Armstrong SA.
    Cancer Res; 2017 Apr 01; 77(7):1753-1762. PubMed ID: 28202522
    [Abstract] [Full Text] [Related]

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