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Journal Abstract Search

119 related items for PubMed ID: 2016719

  • 1. 1,3,8-trisubstituted xanthines. Effects of substitution pattern upon adenosine receptor A1/A2 affinity.
    Erickson RH, Hiner RN, Feeney SW, Blake PR, Rzeszotarski WJ, Hicks RP, Costello DG, Abreu ME.
    J Med Chem; 1991 Apr; 34(4):1431-5. PubMed ID: 2016719
    [Abstract] [Full Text] [Related]

  • 2. 8-Polycycloalkyl-1,3-dipropylxanthines as potent and selective antagonists for A1-adenosine receptors.
    Shimada J, Suzuki F, Nonaka H, Ishii A.
    J Med Chem; 1992 Mar 06; 35(5):924-30. PubMed ID: 1548682
    [Abstract] [Full Text] [Related]

  • 3. Structure-activity relationships of 8-cycloalkyl-1,3-dipropylxanthines as antagonists of adenosine receptors.
    Katsushima T, Nieves L, Wells JN.
    J Med Chem; 1990 Jul 06; 33(7):1906-10. PubMed ID: 1694546
    [Abstract] [Full Text] [Related]

  • 4. Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors.
    Daly JW, Padgett WL, Shamim MT.
    J Med Chem; 1986 Jul 06; 29(7):1305-8. PubMed ID: 3806581
    [Abstract] [Full Text] [Related]

  • 5. Linear and proximal benzo-separated alkylated xanthines as adenosine-receptor antagonists.
    Schneller SW, Ibay AC, Christ WJ, Bruns RF.
    J Med Chem; 1989 Oct 06; 32(10):2247-54. PubMed ID: 2795597
    [Abstract] [Full Text] [Related]

  • 6. Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors.
    Jacobson KA, Kiriasis L, Barone S, Bradbury BJ, Kammula U, Campagne JM, Secunda S, Daly JW, Neumeyer JL, Pfleiderer W.
    J Med Chem; 1989 Aug 06; 32(8):1873-9. PubMed ID: 2754711
    [Abstract] [Full Text] [Related]

  • 7. 7-Deaza-2-phenyladenines: structure-activity relationships of potent A1 selective adenosine receptor antagonists.
    Müller CE, Hide I, Daly JW, Rothenhäusler K, Eger K.
    J Med Chem; 1990 Oct 06; 33(10):2822-8. PubMed ID: 2213835
    [Abstract] [Full Text] [Related]

  • 8. 4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants.
    Sarges R, Howard HR, Browne RG, Lebel LA, Seymour PA, Koe BK.
    J Med Chem; 1990 Aug 06; 33(8):2240-54. PubMed ID: 2374150
    [Abstract] [Full Text] [Related]

  • 9. Mesoionic xanthine analogues: antagonists of adenosine receptors.
    Glennon RA, Tejani-Butt SM, Padgett W, Daly JW.
    J Med Chem; 1984 Oct 06; 27(10):1364-7. PubMed ID: 6090665
    [Abstract] [Full Text] [Related]

  • 10. 8-Aryl-and 8-cycloalkyl-1,3-dipropylxanthines: further potent and selective antagonists for A1-adenosine receptors.
    Shamim MT, Ukena D, Padgett WL, Hong O, Daly JW.
    J Med Chem; 1988 Mar 06; 31(3):613-7. PubMed ID: 3346878
    [Abstract] [Full Text] [Related]

  • 11. Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions.
    Shamim MT, Ukena D, Padgett WL, Daly JW.
    J Med Chem; 1989 Jun 06; 32(6):1231-7. PubMed ID: 2724296
    [Abstract] [Full Text] [Related]

  • 12. 125I-labeled 8-phenylxanthine derivatives: antagonist radioligands for adenosine A1 receptors.
    Linden J, Patel A, Earl CQ, Craig RH, Daluge SM.
    J Med Chem; 1988 Apr 06; 31(4):745-51. PubMed ID: 3351850
    [Abstract] [Full Text] [Related]

  • 13. Effects of substituent size upon adenosine receptor A1/A2 affinity of some newly synthesised 8-cycloalkyl xanthines.
    Castagnino E, Salvatori A, Corsano S, Tacchi P, Martini C, Lucacchini A.
    Drug Des Discov; 1995 Apr 06; 12(4):313-21. PubMed ID: 9040991
    [Abstract] [Full Text] [Related]

  • 14. 8-Azaxanthine derivatives as antagonists of adenosine receptors.
    Franchetti P, Messini L, Cappellacci L, Grifantini M, Lucacchini A, Martini C, Senatore G.
    J Med Chem; 1994 Sep 02; 37(18):2970-5. PubMed ID: 8071944
    [Abstract] [Full Text] [Related]

  • 15. Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors.
    Jacobson KA, Shi D, Gallo-Rodriguez C, Manning M, Müller C, Daly JW, Neumeyer JL, Kiriasis L, Pfleiderer W.
    J Med Chem; 1993 Sep 03; 36(18):2639-44. PubMed ID: 8410976
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and structure-activity relationships of deazaxanthines: analogs of potent A1- and A2-adenosine receptor antagonists.
    Grahner B, Winiwarter S, Lanzner W, Müller CE.
    J Med Chem; 1994 May 13; 37(10):1526-34. PubMed ID: 8182711
    [Abstract] [Full Text] [Related]

  • 17. Trifunctional agents as a design strategy for tailoring ligand properties: irreversible inhibitors of A1 adenosine receptors.
    Boring DL, Ji XD, Zimmet J, Taylor KE, Stiles GL, Jacobson KA.
    Bioconjug Chem; 1991 May 13; 2(2):77-88. PubMed ID: 1868116
    [Abstract] [Full Text] [Related]

  • 18. Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptors.
    Müller CE, Shi D, Manning M, Daly JW.
    J Med Chem; 1993 Oct 29; 36(22):3341-9. PubMed ID: 8230124
    [Abstract] [Full Text] [Related]

  • 19. Structure-activity relationships in a series of 8-substituted xanthines as A1-adenosine receptor antagonists.
    Strappaghetti G, Corsano S, Barbaro R, Giannaccini G, Betti L.
    Bioorg Med Chem; 2001 Mar 29; 9(3):575-83. PubMed ID: 11310591
    [Abstract] [Full Text] [Related]

  • 20. Structure-activity relationships of 8-styrylxanthines as A2-selective adenosine antagonists.
    Jacobson KA, Gallo-Rodriguez C, Melman N, Fischer B, Maillard M, van Bergen A, van Galen PJ, Karton Y.
    J Med Chem; 1993 May 14; 36(10):1333-42. PubMed ID: 8496902
    [Abstract] [Full Text] [Related]

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