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Journal Abstract Search

255 related items for PubMed ID: 20170164

  • 1. A new class of naphthalimide-based antitumor agents that inhibit topoisomerase II and induce lysosomal membrane permeabilization and apoptosis.
    Chen Z, Liang X, Zhang H, Xie H, Liu J, Xu Y, Zhu W, Wang Y, Wang X, Tan S, Kuang D, Qian X.
    J Med Chem; 2010 Mar 25; 53(6):2589-600. PubMed ID: 20170164
    [Abstract] [Full Text] [Related]

  • 2. A ROS-mediated lysosomal-mitochondrial pathway is induced by a novel Amonafide analogue, 7c, in human Hela cervix carcinoma cells.
    Shen K, Sun L, Zhang H, Xu Y, Qian X, Lu Y, Li Q, Ni L, Liu J.
    Cancer Lett; 2013 Jun 10; 333(2):229-38. PubMed ID: 23376642
    [Abstract] [Full Text] [Related]

  • 3. Novel naphthalimide derivatives as potential apoptosis-inducing agents: design, synthesis and biological evaluation.
    Wu A, Xu Y, Qian X, Wang J, Liu J.
    Eur J Med Chem; 2009 Nov 10; 44(11):4674-80. PubMed ID: 19643513
    [Abstract] [Full Text] [Related]

  • 4. Naphthalimides exhibit in vitro antiproliferative and antiangiogenic activities by inhibiting both topoisomerase II (topo II) and receptor tyrosine kinases (RTKs).
    Wang X, Chen Z, Tong L, Tan S, Zhou W, Peng T, Han K, Ding J, Xie H, Xu Y.
    Eur J Med Chem; 2013 Jul 10; 65():477-86. PubMed ID: 23770449
    [Abstract] [Full Text] [Related]

  • 5. Novel naphthalimide-amino acid conjugates with flexible leucine moiety as side chain: design, synthesis and potential antitumor activity.
    Wu A, Xu Y, Qian X.
    Bioorg Med Chem; 2009 Jan 15; 17(2):592-9. PubMed ID: 19109022
    [Abstract] [Full Text] [Related]

  • 6. 5-Non-amino aromatic substituted naphthalimides as potential antitumor agents: Synthesis via Suzuki reaction, antiproliferative activity, and DNA-binding behavior.
    Xie L, Cui J, Qian X, Xu Y, Liu J, Xu R.
    Bioorg Med Chem; 2011 Jan 15; 19(2):961-7. PubMed ID: 21208805
    [Abstract] [Full Text] [Related]

  • 7. Novel tetra-acridine derivatives as dual inhibitors of topoisomerase II and the human proteasome.
    Vispé S, Vandenberghe I, Robin M, Annereau JP, Créancier L, Pique V, Galy JP, Kruczynski A, Barret JM, Bailly C.
    Biochem Pharmacol; 2007 Jun 15; 73(12):1863-72. PubMed ID: 17391647
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and biological evaluation of distamycin analogues - new potential anticancer agents.
    Drozdowska D, Rusak M, Miltyk W, Midura-Nowaczek K.
    Arch Pharm (Weinheim); 2009 Feb 15; 342(2):87-93. PubMed ID: 19173336
    [Abstract] [Full Text] [Related]

  • 9. Structure-activity relationship (SAR) of parthenin analogues with pro-apoptotic activity: Development of novel anti-cancer leads.
    Shah BA, Kaur R, Gupta P, Kumar A, Sethi VK, Andotra SS, Singh J, Saxena AK, Taneja SC.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4394-8. PubMed ID: 19501509
    [Abstract] [Full Text] [Related]

  • 10. Novel naphthalimide-benzoic acid conjugates as potential apoptosis-inducing agents: design, synthesis, and biological activity.
    Wu A, Mei P, Xu Y, Qian X.
    Chem Biol Drug Des; 2011 Dec 01; 78(6):941-7. PubMed ID: 21958160
    [Abstract] [Full Text] [Related]

  • 11. Substitution at the F-ring N-imide of the indolocarbazole antitumor drug NB-506 increases the cytotoxicity, DNA binding, and topoisomerase I inhibition activities.
    Bailly C, Qu X, Chaires JB, Colson P, Houssier C, Ohkubo M, Nishimura S, Yoshinari T.
    J Med Chem; 1999 Jul 29; 42(15):2927-35. PubMed ID: 10425102
    [Abstract] [Full Text] [Related]

  • 12. Design of new topoisomerase II inhibitors based upon a quinobenzoxazine self-assembly model.
    Zeng Q, Kwok Y, Kerwin SM, Mangold G, Hurley LH.
    J Med Chem; 1998 Oct 22; 41(22):4273-8. PubMed ID: 9784102
    [Abstract] [Full Text] [Related]

  • 13. Molecular modelling studies, synthesis and biological activity of a series of novel bisnaphthalimides and their development as new DNA topoisomerase II inhibitors.
    Filosa R, Peduto A, Micco SD, Caprariis Pd, Festa M, Petrella A, Capranico G, Bifulco G.
    Bioorg Med Chem; 2009 Jan 01; 17(1):13-24. PubMed ID: 19058969
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.
    Zhuo ST, Li CY, Hu MH, Chen SB, Yao PF, Huang SL, Ou TM, Tan JH, An LK, Li D, Gu LQ, Huang ZS.
    Org Biomol Chem; 2013 Jun 28; 11(24):3989-4005. PubMed ID: 23657605
    [Abstract] [Full Text] [Related]

  • 15. Molecular design, chemical synthesis, and biological evaluation of '4-1' pentacyclic aryl/heteroaryl-imidazonaphthalimides.
    Li F, Cui J, Guo L, Qian X, Ren W, Wang K, Liu F.
    Bioorg Med Chem; 2007 Aug 01; 15(15):5114-21. PubMed ID: 17532640
    [Abstract] [Full Text] [Related]

  • 16. Anticancer Activity and Topoisomerase II Inhibition of Naphthalimides with ω-Hydroxylalkylamine Side-Chains of Different Lengths.
    Tomczyk MD, Byczek-Wyrostek A, Strama K, Wawszków M, Kasprzycki P, Walczak KZ.
    Med Chem; 2019 Aug 01; 15(5):550-560. PubMed ID: 30207241
    [Abstract] [Full Text] [Related]

  • 17. Oxo-heterocyclic fused naphthalimides as antitumor agents: synthesis and biological evaluation.
    Tan S, Yin H, Chen Z, Qian X, Xu Y.
    Eur J Med Chem; 2013 Apr 01; 62():130-8. PubMed ID: 23353750
    [Abstract] [Full Text] [Related]

  • 18. Antitumor agents. Part 227: Studies on novel 4'-O-demethyl-epipodophyllotoxins as antitumor agents targeting topoisomerase II.
    Xiao Z, Bastow KF, Vance JR, Lee KH.
    Bioorg Med Chem; 2004 Jun 15; 12(12):3339-44. PubMed ID: 15158802
    [Abstract] [Full Text] [Related]

  • 19. New benzoxanthone derivatives as topoisomerase inhibitors and DNA cross-linkers.
    Cho HJ, Jung MJ, Woo S, Kim J, Lee ES, Kwon Y, Na Y.
    Bioorg Med Chem; 2010 Feb 15; 18(3):1010-7. PubMed ID: 20093033
    [Abstract] [Full Text] [Related]

  • 20. Sulfur-substituted naphthalimides as photoactivatable anticancer agents: DNA interaction, fluorescence imaging, and phototoxic effects in cultured tumor cells.
    Ott I, Xu Y, Liu J, Kokoschka M, Harlos M, Sheldrick WS, Qian X.
    Bioorg Med Chem; 2008 Aug 01; 16(15):7107-16. PubMed ID: 18644732
    [Abstract] [Full Text] [Related]

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