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Journal Abstract Search

2222 related items for PubMed ID: 20173742

  • 1. The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.
    Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M.
    Nat Cell Biol; 2010 Mar; 12(3):213-23. PubMed ID: 20173742
    [Abstract] [Full Text] [Related]

  • 2. Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.
    Inami Y, Waguri S, Sakamoto A, Kouno T, Nakada K, Hino O, Watanabe S, Ando J, Iwadate M, Yamamoto M, Lee MS, Tanaka K, Komatsu M.
    J Cell Biol; 2011 Apr 18; 193(2):275-84. PubMed ID: 21482715
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  • 6. Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.
    Ichimura Y, Waguri S, Sou YS, Kageyama S, Hasegawa J, Ishimura R, Saito T, Yang Y, Kouno T, Fukutomi T, Hoshii T, Hirao A, Takagi K, Mizushima T, Motohashi H, Lee MS, Yoshimori T, Tanaka K, Yamamoto M, Komatsu M.
    Mol Cell; 2013 Sep 12; 51(5):618-31. PubMed ID: 24011591
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  • 7. Toll-Like Receptor Signaling Induces Nrf2 Pathway Activation through p62-Triggered Keap1 Degradation.
    Yin S, Cao W.
    Mol Cell Biol; 2015 Aug 12; 35(15):2673-83. PubMed ID: 26012548
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  • 9. Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway.
    Kageyama S, Sou YS, Uemura T, Kametaka S, Saito T, Ishimura R, Kouno T, Bedford L, Mayer RJ, Lee MS, Yamamoto M, Waguri S, Tanaka K, Komatsu M.
    J Biol Chem; 2014 Sep 05; 289(36):24944-55. PubMed ID: 25049227
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  • 11. PF-4708671, a specific inhibitor of p70 ribosomal S6 kinase 1, activates Nrf2 by promoting p62-dependent autophagic degradation of Keap1.
    Park JS, Kang DH, Lee DH, Bae SH.
    Biochem Biophys Res Commun; 2015 Oct 23; 466(3):499-504. PubMed ID: 26381178
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  • 13. SPBP is a sulforaphane induced transcriptional coactivator of NRF2 regulating expression of the autophagy receptor p62/SQSTM1.
    Darvekar SR, Elvenes J, Brenne HB, Johansen T, Sjøttem E.
    PLoS One; 2014 Oct 23; 9(1):e85262. PubMed ID: 24416372
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  • 14. Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage.
    Bae SH, Sung SH, Oh SY, Lim JM, Lee SK, Park YN, Lee HE, Kang D, Rhee SG.
    Cell Metab; 2013 Jan 08; 17(1):73-84. PubMed ID: 23274085
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  • 15. Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy.
    Fan W, Tang Z, Chen D, Moughon D, Ding X, Chen S, Zhu M, Zhong Q.
    Autophagy; 2010 Jul 08; 6(5):614-21. PubMed ID: 20495340
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  • 16. MOAP-1-mediated dissociation of p62/SQSTM1 bodies releases Keap1 and suppresses Nrf2 signaling.
    Tan CT, Chang HC, Zhou Q, Yu C, Fu NY, Sabapathy K, Yu VC.
    EMBO Rep; 2021 Jan 07; 22(1):e50854. PubMed ID: 33393215
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  • 17. Arsenic inhibits autophagic flux, activating the Nrf2-Keap1 pathway in a p62-dependent manner.
    Lau A, Zheng Y, Tao S, Wang H, Whitman SA, White E, Zhang DD.
    Mol Cell Biol; 2013 Jun 07; 33(12):2436-46. PubMed ID: 23589329
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  • 18. Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis.
    Stępkowski TM, Kruszewski MK.
    Free Radic Biol Med; 2011 May 01; 50(9):1186-95. PubMed ID: 21295136
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  • 19. Fenofibrate activates Nrf2 through p62-dependent Keap1 degradation.
    Park JS, Kang DH, Lee DH, Bae SH.
    Biochem Biophys Res Commun; 2015 Sep 25; 465(3):542-7. PubMed ID: 26282199
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  • 20. TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis.
    Pan JA, Sun Y, Jiang YP, Bott AJ, Jaber N, Dou Z, Yang B, Chen JS, Catanzaro JM, Du C, Ding WX, Diaz-Meco MT, Moscat J, Ozato K, Lin RZ, Zong WX.
    Mol Cell; 2016 Mar 03; 61(5):720-733. PubMed ID: 26942676
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