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193 related items for PubMed ID: 20179178

  • 1. Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2-alpha and Tfr2-beta isoforms in different tissues.
    Roetto A, Di Cunto F, Pellegrino RM, Hirsch E, Azzolino O, Bondi A, Defilippi I, Carturan S, Miniscalco B, Riondato F, Cilloni D, Silengo L, Altruda F, Camaschella C, Saglio G.
    Blood; 2010 Apr 22; 115(16):3382-9. PubMed ID: 20179178
    [Abstract] [Full Text] [Related]

  • 2. Iron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosis.
    Chua AC, Delima RD, Morgan EH, Herbison CE, Tirnitz-Parker JE, Graham RM, Fleming RE, Britton RS, Bacon BR, Olynyk JK, Trinder D.
    J Hepatol; 2010 Mar 22; 52(3):425-31. PubMed ID: 20133002
    [Abstract] [Full Text] [Related]

  • 3. Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis.
    Kawabata H, Fleming RE, Gui D, Moon SY, Saitoh T, O'Kelly J, Umehara Y, Wano Y, Said JW, Koeffler HP.
    Blood; 2005 Jan 01; 105(1):376-81. PubMed ID: 15345587
    [Abstract] [Full Text] [Related]

  • 4. The erythroid function of transferrin receptor 2 revealed by Tmprss6 inactivation in different models of transferrin receptor 2 knockout mice.
    Nai A, Pellegrino RM, Rausa M, Pagani A, Boero M, Silvestri L, Saglio G, Roetto A, Camaschella C.
    Haematologica; 2014 Jun 01; 99(6):1016-21. PubMed ID: 24658816
    [Abstract] [Full Text] [Related]

  • 5. First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin.
    Wallace DF, Summerville L, Lusby PE, Subramaniam VN.
    Gut; 2005 Jul 01; 54(7):980-6. PubMed ID: 15951546
    [Abstract] [Full Text] [Related]

  • 6. Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe.
    Corradini E, Rozier M, Meynard D, Odhiambo A, Lin HY, Feng Q, Migas MC, Britton RS, Babitt JL, Fleming RE.
    Gastroenterology; 2011 Nov 01; 141(5):1907-14. PubMed ID: 21745449
    [Abstract] [Full Text] [Related]

  • 7. Targeted disruption of the hepatic transferrin receptor 2 gene in mice leads to iron overload.
    Wallace DF, Summerville L, Subramaniam VN.
    Gastroenterology; 2007 Jan 01; 132(1):301-10. PubMed ID: 17241880
    [Abstract] [Full Text] [Related]

  • 8. Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice.
    Delima RD, Chua AC, Tirnitz-Parker JE, Gan EK, Croft KD, Graham RM, Olynyk JK, Trinder D.
    Hepatology; 2012 Aug 01; 56(2):585-93. PubMed ID: 22383097
    [Abstract] [Full Text] [Related]

  • 9. Altered Erythropoiesis in Mouse Models of Type 3 Hemochromatosis.
    Pellegrino RM, Riondato F, Ferbo L, Boero M, Palmieri A, Osella L, Pollicino P, Miniscalco B, Saglio G, Roetto A.
    Biomed Res Int; 2017 Aug 01; 2017():2408941. PubMed ID: 28540293
    [Abstract] [Full Text] [Related]

  • 10. Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload.
    Wallace DF, Summerville L, Crampton EM, Frazer DM, Anderson GJ, Subramaniam VN.
    Hepatology; 2009 Dec 01; 50(6):1992-2000. PubMed ID: 19824072
    [Abstract] [Full Text] [Related]

  • 11. Blunted hepcidin response to inflammation in the absence of Hfe and transferrin receptor 2.
    Wallace DF, McDonald CJ, Ostini L, Subramaniam VN.
    Blood; 2011 Mar 10; 117(10):2960-6. PubMed ID: 21245482
    [Abstract] [Full Text] [Related]

  • 12. Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice.
    Ramos E, Kautz L, Rodriguez R, Hansen M, Gabayan V, Ginzburg Y, Roth MP, Nemeth E, Ganz T.
    Hepatology; 2011 Apr 10; 53(4):1333-41. PubMed ID: 21480335
    [Abstract] [Full Text] [Related]

  • 13. Iron absorption and hepatic iron uptake are increased in a transferrin receptor 2 (Y245X) mutant mouse model of hemochromatosis type 3.
    Drake SF, Morgan EH, Herbison CE, Delima R, Graham RM, Chua AC, Leedman PJ, Fleming RE, Bacon BR, Olynyk JK, Trinder D.
    Am J Physiol Gastrointest Liver Physiol; 2007 Jan 10; 292(1):G323-8. PubMed ID: 16935854
    [Abstract] [Full Text] [Related]

  • 14. Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis.
    Fleming RE, Ahmann JR, Migas MC, Waheed A, Koeffler HP, Kawabata H, Britton RS, Bacon BR, Sly WS.
    Proc Natl Acad Sci U S A; 2002 Aug 06; 99(16):10653-8. PubMed ID: 12134060
    [Abstract] [Full Text] [Related]

  • 15. Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2.
    Schmidt PJ, Fleming MD.
    Am J Hematol; 2012 Jun 06; 87(6):588-95. PubMed ID: 22460705
    [Abstract] [Full Text] [Related]

  • 16. Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression.
    Gao J, Chen J, Kramer M, Tsukamoto H, Zhang AS, Enns CA.
    Cell Metab; 2009 Mar 06; 9(3):217-27. PubMed ID: 19254567
    [Abstract] [Full Text] [Related]

  • 17. Extrahepatic deficiency of transferrin receptor 2 is associated with increased erythropoiesis independent of iron overload.
    Wortham AM, Goldman DC, Chen J, Fleming WH, Zhang AS, Enns CA.
    J Biol Chem; 2020 Mar 20; 295(12):3906-3917. PubMed ID: 32054685
    [Abstract] [Full Text] [Related]

  • 18. Differing impact of the deletion of hemochromatosis-associated molecules HFE and transferrin receptor-2 on the iron phenotype of mice lacking bone morphogenetic protein 6 or hemojuvelin.
    Latour C, Besson-Fournier C, Meynard D, Silvestri L, Gourbeyre O, Aguilar-Martinez P, Schmidt PJ, Fleming MD, Roth MP, Coppin H.
    Hepatology; 2016 Jan 20; 63(1):126-37. PubMed ID: 26406355
    [Abstract] [Full Text] [Related]

  • 19. Lack of Hfe and TfR2 in Macrophages Impairs Iron Metabolism in the Spleen and the Bone Marrow.
    Comità S, Falco P, Mezzanotte M, Vujić Spasić M, Roetto A.
    Int J Mol Sci; 2024 Aug 23; 25(17):. PubMed ID: 39273097
    [Abstract] [Full Text] [Related]

  • 20. Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis.
    Fleming RE, Migas MC, Holden CC, Waheed A, Britton RS, Tomatsu S, Bacon BR, Sly WS.
    Proc Natl Acad Sci U S A; 2000 Feb 29; 97(5):2214-9. PubMed ID: 10681454
    [Abstract] [Full Text] [Related]

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