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Journal Abstract Search


684 related items for PubMed ID: 20185762

  • 1. Activation of peroxisome proliferator-activated receptor-{delta} by GW501516 prevents fatty acid-induced nuclear factor-{kappa}B activation and insulin resistance in skeletal muscle cells.
    Coll T, Alvarez-Guardia D, Barroso E, Gómez-Foix AM, Palomer X, Laguna JC, Vázquez-Carrera M.
    Endocrinology; 2010 Apr; 151(4):1560-9. PubMed ID: 20185762
    [Abstract] [Full Text] [Related]

  • 2. BAIBA attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK-PPARδ-dependent pathway in mice.
    Jung TW, Hwang HJ, Hong HC, Yoo HJ, Baik SH, Choi KM.
    Diabetologia; 2015 Sep; 58(9):2096-105. PubMed ID: 26105792
    [Abstract] [Full Text] [Related]

  • 3. The peroxisome proliferator-activated receptor β/δ (PPARβ/δ) agonist GW501516 prevents TNF-α-induced NF-κB activation in human HaCaT cells by reducing p65 acetylation through AMPK and SIRT1.
    Barroso E, Eyre E, Palomer X, Vázquez-Carrera M.
    Biochem Pharmacol; 2011 Feb 15; 81(4):534-43. PubMed ID: 21146504
    [Abstract] [Full Text] [Related]

  • 4. Activation of PPARdelta up-regulates fatty acid oxidation and energy uncoupling genes of mitochondria and reduces palmitate-induced apoptosis in pancreatic beta-cells.
    Wan J, Jiang L, Lü Q, Ke L, Li X, Tong N.
    Biochem Biophys Res Commun; 2010 Jan 15; 391(3):1567-72. PubMed ID: 20040361
    [Abstract] [Full Text] [Related]

  • 5. Agonist-induced activation releases peroxisome proliferator-activated receptor beta/delta from its inhibition by palmitate-induced nuclear factor-kappaB in skeletal muscle cells.
    Jové M, Laguna JC, Vázquez-Carrera M.
    Biochim Biophys Acta; 2005 May 01; 1734(1):52-61. PubMed ID: 15866483
    [Abstract] [Full Text] [Related]

  • 6. Activation of peroxisome proliferator-activated receptor beta/delta inhibits lipopolysaccharide-induced cytokine production in adipocytes by lowering nuclear factor-kappaB activity via extracellular signal-related kinase 1/2.
    Rodríguez-Calvo R, Serrano L, Coll T, Moullan N, Sánchez RM, Merlos M, Palomer X, Laguna JC, Michalik L, Wahli W, Vázquez-Carrera M.
    Diabetes; 2008 Aug 01; 57(8):2149-57. PubMed ID: 18443198
    [Abstract] [Full Text] [Related]

  • 7. Cyclooxygenase 2 inhibition exacerbates palmitate-induced inflammation and insulin resistance in skeletal muscle cells.
    Coll T, Palomer X, Blanco-Vaca F, Escolà-Gil JC, Sánchez RM, Laguna JC, Vázquez-Carrera M.
    Endocrinology; 2010 Feb 01; 151(2):537-48. PubMed ID: 20022932
    [Abstract] [Full Text] [Related]

  • 8. METRNL attenuates lipid-induced inflammation and insulin resistance via AMPK or PPARδ-dependent pathways in skeletal muscle of mice.
    Jung TW, Lee SH, Kim HC, Bang JS, Abd El-Aty AM, Hacımüftüoğlu A, Shin YK, Jeong JH.
    Exp Mol Med; 2018 Sep 13; 50(9):1-11. PubMed ID: 30213948
    [Abstract] [Full Text] [Related]

  • 9. Protective Effect of Unsaturated Fatty Acids on Palmitic Acid-Induced Toxicity in Skeletal Muscle Cells is not Mediated by PPARδ Activation.
    Tumova J, Malisova L, Andel M, Trnka J.
    Lipids; 2015 Oct 13; 50(10):955-64. PubMed ID: 26255030
    [Abstract] [Full Text] [Related]

  • 10. The peroxisome proliferator-activated receptor (PPAR) β/δ agonist GW501516 inhibits IL-6-induced signal transducer and activator of transcription 3 (STAT3) activation and insulin resistance in human liver cells.
    Serrano-Marco L, Barroso E, El Kochairi I, Palomer X, Michalik L, Wahli W, Vázquez-Carrera M.
    Diabetologia; 2012 Mar 13; 55(3):743-51. PubMed ID: 22179221
    [Abstract] [Full Text] [Related]

  • 11. Lysophosphatidylcholines activate PPARδ and protect human skeletal muscle cells from lipotoxicity.
    Klingler C, Zhao X, Adhikary T, Li J, Xu G, Häring HU, Schleicher E, Lehmann R, Weigert C.
    Biochim Biophys Acta; 2016 Dec 13; 1861(12 Pt A):1980-1992. PubMed ID: 27697477
    [Abstract] [Full Text] [Related]

  • 12. The PPARdelta agonist, GW501516, promotes fatty acid oxidation but has no direct effect on glucose utilisation or insulin sensitivity in rat L6 skeletal muscle cells.
    Dimopoulos N, Watson M, Green C, Hundal HS.
    FEBS Lett; 2007 Oct 02; 581(24):4743-8. PubMed ID: 17869249
    [Abstract] [Full Text] [Related]

  • 13. Carnitine palmitoyltransferase-1 up-regulation by PPAR-β/δ prevents lipid-induced endothelial dysfunction.
    Toral M, Romero M, Jiménez R, Mahmoud AM, Barroso E, Gómez-Guzmán M, Sánchez M, Cogolludo Á, García-Redondo AB, Briones AM, Vázquez-Carrera M, Pérez-Vizcaíno F, Duarte J.
    Clin Sci (Lond); 2015 Nov 02; 129(9):823-37. PubMed ID: 26253087
    [Abstract] [Full Text] [Related]

  • 14. Suppression of plasma free fatty acids upregulates peroxisome proliferator-activated receptor (PPAR) alpha and delta and PPAR coactivator 1alpha in human skeletal muscle, but not lipid regulatory genes.
    Watt MJ, Southgate RJ, Holmes AG, Febbraio MA.
    J Mol Endocrinol; 2004 Oct 02; 33(2):533-44. PubMed ID: 15525607
    [Abstract] [Full Text] [Related]

  • 15. Different impacts of saturated and unsaturated free fatty acids on COX-2 expression in C(2)C(12) myotubes.
    Kadotani A, Tsuchiya Y, Hatakeyama H, Katagiri H, Kanzaki M.
    Am J Physiol Endocrinol Metab; 2009 Dec 02; 297(6):E1291-303. PubMed ID: 19755671
    [Abstract] [Full Text] [Related]

  • 16. In vitro responsiveness of human muscle cell peroxisome proliferator-activated receptor δ reflects donors' insulin sensitivity in vivo.
    Ordelheide AM, Heni M, Thamer C, Machicao F, Fritsche A, Stefan N, Häring HU, Staiger H.
    Eur J Clin Invest; 2011 Dec 02; 41(12):1323-9. PubMed ID: 21615395
    [Abstract] [Full Text] [Related]

  • 17. Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet.
    Nagasawa T, Inada Y, Nakano S, Tamura T, Takahashi T, Maruyama K, Yamazaki Y, Kuroda J, Shibata N.
    Eur J Pharmacol; 2006 Apr 24; 536(1-2):182-91. PubMed ID: 16574099
    [Abstract] [Full Text] [Related]

  • 18. Role of AMP kinase and PPARdelta in the regulation of lipid and glucose metabolism in human skeletal muscle.
    Krämer DK, Al-Khalili L, Guigas B, Leng Y, Garcia-Roves PM, Krook A.
    J Biol Chem; 2007 Jul 06; 282(27):19313-20. PubMed ID: 17500064
    [Abstract] [Full Text] [Related]

  • 19. SUMO-Specific Protease 2 (SENP2) Is an Important Regulator of Fatty Acid Metabolism in Skeletal Muscle.
    Koo YD, Choi JW, Kim M, Chae S, Ahn BY, Kim M, Oh BC, Hwang D, Seol JH, Kim YB, Park YJ, Chung SS, Park KS.
    Diabetes; 2015 Jul 06; 64(7):2420-31. PubMed ID: 25784542
    [Abstract] [Full Text] [Related]

  • 20. Peroxisome proliferator-activated receptor delta-agonist, GW501516, ameliorates insulin resistance, improves dyslipidaemia in monosodium L-glutamate metabolic syndrome mice.
    Chen W, Wang LL, Liu HY, Long L, Li S.
    Basic Clin Pharmacol Toxicol; 2008 Sep 06; 103(3):240-6. PubMed ID: 18684227
    [Abstract] [Full Text] [Related]


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