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Journal Abstract Search

385 related items for PubMed ID: 20200974

  • 1. TNF-alpha mediates diabetes-enhanced chondrocyte apoptosis during fracture healing and stimulates chondrocyte apoptosis through FOXO1.
    Kayal RA, Siqueira M, Alblowi J, McLean J, Krothapalli N, Faibish D, Einhorn TA, Gerstenfeld LC, Graves DT.
    J Bone Miner Res; 2010 Jul; 25(7):1604-15. PubMed ID: 20200974
    [Abstract] [Full Text] [Related]

  • 2. High levels of tumor necrosis factor-alpha contribute to accelerated loss of cartilage in diabetic fracture healing.
    Alblowi J, Kayal RA, Siqueira M, McKenzie E, Krothapalli N, McLean J, Conn J, Nikolajczyk B, Einhorn TA, Gerstenfeld L, Graves DT.
    Am J Pathol; 2009 Oct; 175(4):1574-85. PubMed ID: 19745063
    [Abstract] [Full Text] [Related]

  • 3. FOXO 1 deletion in chondrocytes rescues diabetes-impaired fracture healing by restoring angiogenesis and reducing apoptosis.
    Alharbi MA, Graves DT.
    Front Endocrinol (Lausanne); 2023 Oct; 14():1136117. PubMed ID: 37576976
    [Abstract] [Full Text] [Related]

  • 4. Impaired wound healing in mouse models of diabetes is mediated by TNF-alpha dysregulation and associated with enhanced activation of forkhead box O1 (FOXO1).
    Siqueira MF, Li J, Chehab L, Desta T, Chino T, Krothpali N, Behl Y, Alikhani M, Yang J, Braasch C, Graves DT.
    Diabetologia; 2010 Feb; 53(2):378-88. PubMed ID: 19902175
    [Abstract] [Full Text] [Related]

  • 5. Impaired fracture healing in the absence of TNF-alpha signaling: the role of TNF-alpha in endochondral cartilage resorption.
    Gerstenfeld LC, Cho TJ, Kon T, Aizawa T, Tsay A, Fitch J, Barnes GL, Graves DT, Einhorn TA.
    J Bone Miner Res; 2003 Sep; 18(9):1584-92. PubMed ID: 12968667
    [Abstract] [Full Text] [Related]

  • 6. Diminished bone formation during diabetic fracture healing is related to the premature resorption of cartilage associated with increased osteoclast activity.
    Kayal RA, Tsatsas D, Bauer MA, Allen B, Al-Sebaei MO, Kakar S, Leone CW, Morgan EF, Gerstenfeld LC, Einhorn TA, Graves DT.
    J Bone Miner Res; 2007 Apr; 22(4):560-8. PubMed ID: 17243865
    [Abstract] [Full Text] [Related]

  • 7. Deletion of FOXO1 in chondrocytes rescues the effect of diabetes on mechanical strength in fracture healing.
    Lu Y, Alharbi M, Zhang C, O'Connor JP, Graves DT.
    Bone; 2019 Jun; 123():159-167. PubMed ID: 30904630
    [Abstract] [Full Text] [Related]

  • 8. Tumor necrosis factor alpha (TNF-alpha) coordinately regulates the expression of specific matrix metalloproteinases (MMPS) and angiogenic factors during fracture healing.
    Lehmann W, Edgar CM, Wang K, Cho TJ, Barnes GL, Kakar S, Graves DT, Rueger JM, Gerstenfeld LC, Einhorn TA.
    Bone; 2005 Feb; 36(2):300-10. PubMed ID: 15780956
    [Abstract] [Full Text] [Related]

  • 9. Bax deficiency in mice increases cartilage production during fracture repair through a mechanism involving increased chondrocyte proliferation without changes in apoptosis.
    Rundle CH, Wang X, Sheng MH, Wergedal JE, Lau KH, Mohan S.
    Bone; 2008 Nov; 43(5):880-8. PubMed ID: 18708175
    [Abstract] [Full Text] [Related]

  • 10. Chemokine expression is upregulated in chondrocytes in diabetic fracture healing.
    Alblowi J, Tian C, Siqueira MF, Kayal RA, McKenzie E, Behl Y, Gerstenfeld L, Einhorn TA, Graves DT.
    Bone; 2013 Mar; 53(1):294-300. PubMed ID: 23262028
    [Abstract] [Full Text] [Related]

  • 11. Impaired intramembranous bone formation during bone repair in the absence of tumor necrosis factor-alpha signaling.
    Gerstenfeld LC, Cho TJ, Kon T, Aizawa T, Cruceta J, Graves BD, Einhorn TA.
    Cells Tissues Organs; 2001 Mar; 169(3):285-94. PubMed ID: 11455125
    [Abstract] [Full Text] [Related]

  • 12. Diabetes reduces mesenchymal stem cells in fracture healing through a TNFα-mediated mechanism.
    Ko KI, Coimbra LS, Tian C, Alblowi J, Kayal RA, Einhorn TA, Gerstenfeld LC, Pignolo RJ, Graves DT.
    Diabetologia; 2015 Mar; 58(3):633-642. PubMed ID: 25563724
    [Abstract] [Full Text] [Related]

  • 13. Chondrocytes Promote Vascularization in Fracture Healing Through a FOXO1-Dependent Mechanism.
    Zhang C, Feinberg D, Alharbi M, Ding Z, Lu C, O'Connor JP, Graves DT.
    J Bone Miner Res; 2019 Mar; 34(3):547-556. PubMed ID: 30347467
    [Abstract] [Full Text] [Related]

  • 14. TNFα contributes to diabetes impaired angiogenesis in fracture healing.
    Lim JC, Ko KI, Mattos M, Fang M, Zhang C, Feinberg D, Sindi H, Li S, Alblowi J, Kayal RA, Einhorn TA, Gerstenfeld LC, Graves DT.
    Bone; 2017 Jun; 99():26-38. PubMed ID: 28285015
    [Abstract] [Full Text] [Related]

  • 15. FOXO1 Deletion Reverses the Effect of Diabetic-Induced Impaired Fracture Healing.
    Alharbi MA, Zhang C, Lu C, Milovanova TN, Yi L, Ryu JD, Jiao H, Dong G, O'Connor JP, Graves DT.
    Diabetes; 2018 Dec; 67(12):2682-2694. PubMed ID: 30279162
    [Abstract] [Full Text] [Related]

  • 16. FOXO1 plays an important role in enhanced microvascular cell apoptosis and microvascular cell loss in type 1 and type 2 diabetic rats.
    Behl Y, Krothapalli P, Desta T, Roy S, Graves DT.
    Diabetes; 2009 Apr; 58(4):917-25. PubMed ID: 19168598
    [Abstract] [Full Text] [Related]

  • 17. Diabetes causes the accelerated loss of cartilage during fracture repair which is reversed by insulin treatment.
    Kayal RA, Alblowi J, McKenzie E, Krothapalli N, Silkman L, Gerstenfeld L, Einhorn TA, Graves DT.
    Bone; 2009 Feb; 44(2):357-63. PubMed ID: 19010456
    [Abstract] [Full Text] [Related]

  • 18. Dehydroabietic acid reverses TNF-α-induced the activation of FOXO1 and suppression of TGF-β1/Smad signaling in human adult dermal fibroblasts.
    Wang XW, Yu Y, Gu L.
    Int J Clin Exp Pathol; 2014 Feb; 7(12):8616-26. PubMed ID: 25674226
    [Abstract] [Full Text] [Related]

  • 19. FOXO1 functions as a master switch that regulates gene expression necessary for tumor necrosis factor-induced fibroblast apoptosis.
    Alikhani M, Alikhani Z, Graves DT.
    J Biol Chem; 2005 Apr 01; 280(13):12096-102. PubMed ID: 15632117
    [Abstract] [Full Text] [Related]

  • 20. Forkhead box protein O1 mediates apoptosis in a cancer cervical cell line treated with the antitumor agent tumor necrosis factor-α.
    Zhang B, Gui L, Zhu L, Zhao X, Yang Y, Li Q.
    Genet Mol Res; 2015 Jul 06; 14(3):7446-54. PubMed ID: 26214423
    [Abstract] [Full Text] [Related]

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