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Journal Abstract Search

178 related items for PubMed ID: 2020764

  • 21. Pharmacokinetic/pharmacodynamic modeling identifies SN30000 and SN29751 as tirapazamine analogues with improved tissue penetration and hypoxic cell killing in tumors.
    Hicks KO, Siim BG, Jaiswal JK, Pruijn FB, Fraser AM, Patel R, Hogg A, Liyanage HD, Dorie MJ, Brown JM, Denny WA, Hay MP, Wilson WR.
    Clin Cancer Res; 2010 Oct 15; 16(20):4946-57. PubMed ID: 20732963
    [Abstract] [Full Text] [Related]

  • 22. Radiosensitization of hypoxic cells in vivo by SR 2508 at low radiation doses: a preliminary report.
    Brown JM, Yu NY.
    Int J Radiat Oncol Biol Phys; 1984 Aug 15; 10(8):1207-12. PubMed ID: 6236184
    [Abstract] [Full Text] [Related]

  • 23. Second-generation 1,2,4-benzotriazine 1,4-di-N-oxide bioreductive anti-tumor agents: pharmacology and activity in vitro and in vivo.
    Minchinton AI, Lemmon MJ, Tracy M, Pollart DJ, Martinez AP, Tosto LM, Brown JM.
    Int J Radiat Oncol Biol Phys; 1992 Aug 15; 22(4):701-5. PubMed ID: 1544841
    [Abstract] [Full Text] [Related]

  • 24. Implantable polymers for tirapazamine treatments of experimental intracranial malignant glioma.
    Yuan X, Tabassi K, Williams JA.
    Radiat Oncol Investig; 1999 Aug 15; 7(4):218-30. PubMed ID: 10492162
    [Abstract] [Full Text] [Related]

  • 25. The effect of the hypoxic cell drug SR-4233 alone or combined with the ionizing radiations on two human tumor cell lines having different radiosensitivity.
    Lambin P, Guichard M, Chavaudra N, Malaise EP.
    Radiother Oncol; 1992 Jul 15; 24(3):201-4. PubMed ID: 1410575
    [Abstract] [Full Text] [Related]

  • 26. Radiosensitization of a mouse tumor model by sustained intra-tumoral release of etanidazole and tirapazamine using a biodegradable polymer implant device.
    Yapp DT, Lloyd DK, Zhu J, Lehnert S.
    Radiother Oncol; 1999 Oct 15; 53(1):77-84. PubMed ID: 10624857
    [Abstract] [Full Text] [Related]

  • 27. Radiosensitization in multifraction schedules. II. Greater sensitization by 2-nitroimidazoles than by oxygen.
    Taylor YC, Brown JM.
    Radiat Res; 1987 Oct 15; 112(1):134-45. PubMed ID: 3659294
    [Abstract] [Full Text] [Related]

  • 28. Hypoxia-selective agents derived from quinoxaline 1,4-di-N-oxides.
    Monge A, Palop JA, López de Ceráin A, Senador V, Martínez-Crespo FJ, Sainz Y, Narro S, García E, de Miguel C, González M.
    J Med Chem; 1995 May 12; 38(10):1786-92. PubMed ID: 7752202
    [Abstract] [Full Text] [Related]

  • 29. [In vitro oxygen-dependent survival of 2 human cell lines after radiation combined with tirapazamine (SR-4233) and cisplatin].
    Lartigau E, Stern S, Guichard M.
    Cancer Radiother; 2000 May 12; 4(3):217-22. PubMed ID: 10897765
    [Abstract] [Full Text] [Related]

  • 30. Characterization of a CHO cell line resistant to killing by the hypoxic cell cytotoxin SR 4233.
    Giaccia AJ, Biedermann KA, Tosto LM, Minchinton AI, Kovacs MS, Brown JM.
    Int J Radiat Oncol Biol Phys; 1992 May 12; 22(4):681-4. PubMed ID: 1544836
    [Abstract] [Full Text] [Related]

  • 31. In vitro activity of the benzotriazine dioxide SR 4233 against human tumour colony-forming units.
    Hanauske AR, Ross M, Degen D, Hilsenbeck SG, Von Hoff DD.
    Eur J Cancer; 1993 May 12; 29A(3):423-5. PubMed ID: 8398345
    [Abstract] [Full Text] [Related]

  • 32. Evidence for a therapeutic gain when AQ4N or tirapazamine is combined with radiation.
    McKeown SR, Friery OP, McIntyre IA, Hejmadi MV, Patterson LH, Hirst DG.
    Br J Cancer Suppl; 1996 Jul 12; 27():S39-42. PubMed ID: 8763843
    [Abstract] [Full Text] [Related]

  • 33. Bioreductive drugs as post-irradiation sensitizers: comparison of dual function agents with SR 4233 and the mitomycin C analogue EO9.
    Adams GE, Stratford IJ, Edwards HS, Bremner JC, Cole S.
    Int J Radiat Oncol Biol Phys; 1992 Jul 12; 22(4):717-20. PubMed ID: 1544844
    [Abstract] [Full Text] [Related]

  • 34. 4-Fluorobenzylamine and phenylalanine methyl ester conjugates of 2-nitroimidazole: evaluation as hypoxic cell radiosensitizers.
    Garg PK, Garg S, Degraff WG, Zalutsky MR, Mitchell JB.
    Int J Radiat Oncol Biol Phys; 1992 Jul 12; 22(3):593-6. PubMed ID: 1531220
    [Abstract] [Full Text] [Related]

  • 35. Tirapazamine-induced cytotoxicity and DNA damage in transplanted tumors: relationship to tumor hypoxia.
    Siim BG, Menke DR, Dorie MJ, Brown JM.
    Cancer Res; 1997 Jul 15; 57(14):2922-8. PubMed ID: 9230202
    [Abstract] [Full Text] [Related]

  • 36. Therapeutic targets in radiotherapy.
    Brown JM.
    Int J Radiat Oncol Biol Phys; 2001 Feb 01; 49(2):319-26. PubMed ID: 11173124
    [Abstract] [Full Text] [Related]

  • 37. [Radiosensitization by hypoxic cell radiosensitizer--present status of radiosensitizer].
    Murayama C, Mori T.
    Gan No Rinsho; 1990 Oct 01; 36(13):2249-54. PubMed ID: 2147449
    [Abstract] [Full Text] [Related]

  • 38. Hypoxia: new mechanisms for old?
    Adams GE.
    Int J Radiat Oncol Biol Phys; 1991 Mar 01; 20(3):643-4. PubMed ID: 1995555
    [No Abstract] [Full Text] [Related]

  • 39. The effect of glutathione (GSH) depletion in vivo by buthionine sulfoximine (BSO) on the radiosensitization of SR 2508.
    Kramer RA, Soble M, Howes AE, Montoya VP.
    Int J Radiat Oncol Biol Phys; 1989 May 01; 16(5):1325-9. PubMed ID: 2523885
    [Abstract] [Full Text] [Related]

  • 40. Effects of hypoxic cell radiosensitizer doranidazole (PR-350) on the radioresponse of murine and human tumor cells in vitro and in vivo.
    Yahiro T, Masui S, Kubota N, Yamada K, Kobayashi A, Kishii K.
    J Radiat Res; 2005 Sep 01; 46(3):363-72. PubMed ID: 16210793
    [Abstract] [Full Text] [Related]

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