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189 related items for PubMed ID: 20219849

  • 1. Adenoviral-mediated overexpression of DDAH improves vascular tone regulation.
    Torondel B, Nandi M, Kelly P, Wojciak-Stothard B, Fleming I, Leiper J.
    Vasc Med; 2010 Jun; 15(3):205-13. PubMed ID: 20219849
    [Abstract] [Full Text] [Related]

  • 2. Protection of DDAH2 overexpression against homocysteine-induced impairments of DDAH/ADMA/NOS/NO pathway in endothelial cells.
    Liu LH, Guo Z, Feng M, Wu ZZ, He ZM, Xiong Y.
    Cell Physiol Biochem; 2012 Jun; 30(6):1413-22. PubMed ID: 23171931
    [Abstract] [Full Text] [Related]

  • 3. Overexpression of dimethylarginine dimethylaminohydrolase inhibits asymmetric dimethylarginine-induced endothelial dysfunction in the cerebral circulation.
    Dayoub H, Rodionov RN, Lynch C, Cooke JP, Arning E, Bottiglieri T, Lentz SR, Faraci FM.
    Stroke; 2008 Jan; 39(1):180-4. PubMed ID: 18063827
    [Abstract] [Full Text] [Related]

  • 4. Disruption of methylarginine metabolism impairs vascular homeostasis.
    Leiper J, Nandi M, Torondel B, Murray-Rust J, Malaki M, O'Hara B, Rossiter S, Anthony S, Madhani M, Selwood D, Smith C, Wojciak-Stothard B, Rudiger A, Stidwill R, McDonald NQ, Vallance P.
    Nat Med; 2007 Feb; 13(2):198-203. PubMed ID: 17273169
    [Abstract] [Full Text] [Related]

  • 5. Reduced Renal Methylarginine Metabolism Protects against Progressive Kidney Damage.
    Tomlinson JA, Caplin B, Boruc O, Bruce-Cobbold C, Cutillas P, Dormann D, Faull P, Grossman RC, Khadayate S, Mas VR, Nitsch DD, Wang Z, Norman JT, Wilcox CS, Wheeler DC, Leiper J.
    J Am Soc Nephrol; 2015 Dec; 26(12):3045-59. PubMed ID: 25855779
    [Abstract] [Full Text] [Related]

  • 6. Enhancing kidney DDAH-1 expression by adenovirus delivery reduces ADMA and ameliorates diabetic nephropathy.
    Wetzel MD, Gao T, Stanley K, Cooper TK, Morris SM, Awad AS.
    Am J Physiol Renal Physiol; 2020 Feb 01; 318(2):F509-F517. PubMed ID: 31904280
    [Abstract] [Full Text] [Related]

  • 7. Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine.
    Hu X, Atzler D, Xu X, Zhang P, Guo H, Lu Z, Fassett J, Schwedhelm E, Böger RH, Bache RJ, Chen Y.
    Arterioscler Thromb Vasc Biol; 2011 Jul 01; 31(7):1540-6. PubMed ID: 21493890
    [Abstract] [Full Text] [Related]

  • 8. Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia.
    Dayal S, Rodionov RN, Arning E, Bottiglieri T, Kimoto M, Murry DJ, Cooke JP, Faraci FM, Lentz SR.
    Am J Physiol Heart Circ Physiol; 2008 Aug 01; 295(2):H816-25. PubMed ID: 18567702
    [Abstract] [Full Text] [Related]

  • 9. Regulation of the ADMA-DDAH system in endothelial cells: a novel mechanism for the sterol response element binding proteins, SREBP1c and -2.
    Ivashchenko CY, Bradley BT, Ao Z, Leiper J, Vallance P, Johns DG.
    Am J Physiol Heart Circ Physiol; 2010 Jan 01; 298(1):H251-8. PubMed ID: 19915177
    [Abstract] [Full Text] [Related]

  • 10. Dimethylarginine dimethylaminohydrolase-2 deficiency promotes vascular regeneration and attenuates pathological angiogenesis.
    Lange C, Mowat F, Sayed H, Mehad M, Duluc L, Piper S, Luhmann U, Nandi M, Kelly P, Smith A, Ali R, Leiper J, Bainbridge J.
    Exp Eye Res; 2016 Jun 01; 147():148-155. PubMed ID: 27181226
    [Abstract] [Full Text] [Related]

  • 11. Dimethylarginine dimethylaminohydrolase-1 (DDAH1) is frequently upregulated in prostate cancer, and its overexpression conveys tumor growth and angiogenesis by metabolizing asymmetric dimethylarginine (ADMA).
    Reddy KRK, Dasari C, Duscharla D, Supriya B, Ram NS, Surekha MV, Kumar JM, Ummanni R.
    Angiogenesis; 2018 Feb 01; 21(1):79-94. PubMed ID: 29150732
    [Abstract] [Full Text] [Related]

  • 12. Gene transfer of dimethylarginine dimethylaminohydrolase-2 improves the impairments of DDAH/ADMA/NOS/NO pathway in endothelial cells induced by lysophosphatidylcholine.
    Feng M, Liu L, Guo Z, Xiong Y.
    Eur J Pharmacol; 2008 Apr 14; 584(1):49-56. PubMed ID: 18342305
    [Abstract] [Full Text] [Related]

  • 13. Role of asymmetric dimethylarginine in vascular injury in transgenic mice overexpressing dimethylarginie dimethylaminohydrolase 2.
    Hasegawa K, Wakino S, Tatematsu S, Yoshioka K, Homma K, Sugano N, Kimoto M, Hayashi K, Itoh H.
    Circ Res; 2007 Jul 20; 101(2):e2-10. PubMed ID: 17601800
    [Abstract] [Full Text] [Related]

  • 14. Role of dimethylarginine dimethylaminohydrolases in the regulation of endothelial nitric oxide production.
    Pope AJ, Karrupiah K, Kearns PN, Xia Y, Cardounel AJ.
    J Biol Chem; 2009 Dec 18; 284(51):35338-47. PubMed ID: 19820234
    [Abstract] [Full Text] [Related]

  • 15. Dimethylarginine dimethylaminohydrolase 1 modulates endothelial cell growth through nitric oxide and Akt.
    Zhang P, Hu X, Xu X, Chen Y, Bache RJ.
    Arterioscler Thromb Vasc Biol; 2011 Apr 18; 31(4):890-7. PubMed ID: 21212404
    [Abstract] [Full Text] [Related]

  • 16. Piper sarmentosum Promotes Endothelial Nitric Oxide Production by Reducing Asymmetric Dimethylarginine in Tumor Necrosis Factor-α-Induced Human Umbilical Vein Endothelial Cells.
    Sundar UM, Ugusman A, Chua HK, Latip J, Aminuddin A.
    Front Pharmacol; 2019 Apr 18; 10():1033. PubMed ID: 31607906
    [Abstract] [Full Text] [Related]

  • 17. Asymmetric Dimethylarginine Enables Depolarizing Spikes and Vasospasm in Mesenteric and Coronary Resistance Arteries.
    Ng YYH, Dora KA, Lemmey HAL, Lin J, Alden J, Wallis L, Donovan L, Shorthose O, Leiper FC, Leiper J, Garland CJ.
    Hypertension; 2024 Apr 18; 81(4):764-775. PubMed ID: 38226470
    [Abstract] [Full Text] [Related]

  • 18. Sequence variation in DDAH1 and DDAH2 genes is strongly and additively associated with serum ADMA concentrations in individuals with type 2 diabetes.
    Abhary S, Burdon KP, Kuot A, Javadiyan S, Whiting MJ, Kasmeridis N, Petrovsky N, Craig JE.
    PLoS One; 2010 Mar 01; 5(3):e9462. PubMed ID: 20209122
    [Abstract] [Full Text] [Related]

  • 19. Genetic variation in the dimethylarginine dimethylaminohydrolase 1 gene (DDAH1) is related to asymmetric dimethylarginine (ADMA) levels, but not to endothelium-dependent vasodilation.
    Lind L, Ingelsson E, Kumar J, Syvänen AC, Axelsson T, Teerlink T.
    Vasc Med; 2013 Aug 01; 18(4):192-9. PubMed ID: 23892448
    [Abstract] [Full Text] [Related]

  • 20. Dimethylarginine dimethylaminohydrolase-2 overexpression improves impaired nitric oxide synthesis of endothelial cells induced by glycated protein.
    Lu CW, Xiong Y, He P.
    Nitric Oxide; 2007 Feb 01; 16(1):94-103. PubMed ID: 16979918
    [Abstract] [Full Text] [Related]

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