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3. Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin. Spycher C, Miller ES, Townsend K, Pavic L, Morrice NA, Janscak P, Stewart GS, Stucki M. J Cell Biol; 2008 Apr 21; 181(2):227-40. PubMed ID: 18411308 [Abstract] [Full Text] [Related]
4. MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks. Wu L, Luo K, Lou Z, Chen J. Proc Natl Acad Sci U S A; 2008 Aug 12; 105(32):11200-5. PubMed ID: 18678890 [Abstract] [Full Text] [Related]
5. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template. Williams RS, Williams JS, Tainer JA. Biochem Cell Biol; 2007 Aug 12; 85(4):509-20. PubMed ID: 17713585 [Abstract] [Full Text] [Related]
7. Interplay with the Mre11-Rad50-Nbs1 complex and phosphorylation by GSK3β implicate human B-Myb in DNA-damage signaling. Henrich SM, Usadel C, Werwein E, Burdova K, Janscak P, Ferrari S, Hess D, Klempnauer KH. Sci Rep; 2017 Jan 27; 7():41663. PubMed ID: 28128338 [Abstract] [Full Text] [Related]
13. Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin. Melander F, Bekker-Jensen S, Falck J, Bartek J, Mailand N, Lukas J. J Cell Biol; 2008 Apr 21; 181(2):213-26. PubMed ID: 18411307 [Abstract] [Full Text] [Related]
15. The Mre11/Rad50/Nbs1 complex interacts with the mismatch repair system and contributes to temozolomide-induced G2 arrest and cytotoxicity. Mirzoeva OK, Kawaguchi T, Pieper RO. Mol Cancer Ther; 2006 Nov 21; 5(11):2757-66. PubMed ID: 17121922 [Abstract] [Full Text] [Related]
18. NBS1 is regulated by two kind of mechanisms: ATM-dependent complex formation with MRE11 and RAD50, and cell cycle-dependent degradation of protein. Zhou H, Kawamura K, Yanagihara H, Kobayashi J, Zhang-Akiyama QM. J Radiat Res; 2017 Jul 01; 58(4):487-494. PubMed ID: 28369484 [Abstract] [Full Text] [Related]
19. Nibrin forkhead-associated domain and breast cancer C-terminal domain are both required for nuclear focus formation and phosphorylation. Cerosaletti KM, Concannon P. J Biol Chem; 2003 Jun 13; 278(24):21944-51. PubMed ID: 12679336 [Abstract] [Full Text] [Related]