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157 related items for PubMed ID: 2022647

  • 1. Purification and partial sequence analysis of pp185, the major cellular substrate of the insulin receptor tyrosine kinase.
    Rothenberg PL, Lane WS, Karasik A, Backer J, White M, Kahn CR.
    J Biol Chem; 1991 May 05; 266(13):8302-11. PubMed ID: 2022647
    [Abstract] [Full Text] [Related]

  • 2. Characterization of an endogenous substrate of the insulin receptor in cultured cells.
    White MF, Stegmann EW, Dull TJ, Ullrich A, Kahn CR.
    J Biol Chem; 1987 Jul 15; 262(20):9769-77. PubMed ID: 2439512
    [Abstract] [Full Text] [Related]

  • 3. Insulin stimulates tyrosine phosphorylation of multiple high molecular weight substrates in Fao hepatoma cells.
    Miralpeix M, Sun XJ, Backer JM, Myers MG, Araki E, White MF.
    Biochemistry; 1992 Sep 22; 31(37):9031-9. PubMed ID: 1382584
    [Abstract] [Full Text] [Related]

  • 4. Insulin and insulinomimetic agents induce activation of phosphatidylinositol 3'-kinase upon its association with pp185 (IRS-1) in intact rat livers.
    Hadari YR, Tzahar E, Nadiv O, Rothenberg P, Roberts CT, LeRoith D, Yarden Y, Zick Y.
    J Biol Chem; 1992 Sep 05; 267(25):17483-6. PubMed ID: 1381348
    [Abstract] [Full Text] [Related]

  • 5. Insulin-receptor autophosphorylation and endogenous substrate phosphorylation in human adipocytes from control, obese, and NIDDM subjects.
    Thies RS, Molina JM, Ciaraldi TP, Freidenberg GR, Olefsky JM.
    Diabetes; 1990 Feb 05; 39(2):250-9. PubMed ID: 2227134
    [Abstract] [Full Text] [Related]

  • 6. Tyrosine phosphorylation of pp185 by insulin receptor kinase in a cell-free system.
    Tashiro-Hashimoto Y, Tobe K, Koshio O, Izumi T, Takaku F, Akanuma Y, Kasuga M.
    J Biol Chem; 1989 Apr 25; 264(12):6879-85. PubMed ID: 2468662
    [Abstract] [Full Text] [Related]

  • 7. Analysis of insulin receptor phosphorylation sites in intact rat liver cells by two-dimensional phosphopeptide mapping. Predominance of the tris-phosphorylated form of the kinase domain after stimulation by insulin.
    Issad T, Tavaré JM, Denton RM.
    Biochem J; 1991 Apr 01; 275 ( Pt 1)(Pt 1):15-21. PubMed ID: 1708233
    [Abstract] [Full Text] [Related]

  • 8. Concanavalin A-induced receptor aggregation stimulates the tyrosine kinase activity of the insulin receptor in intact cells.
    Shiba T, Tobe K, Koshio O, Yamamoto R, Shibasaki Y, Matsumoto N, Toyoshima S, Osawa T, Akanuma Y, Takaku F.
    Biochem J; 1990 May 01; 267(3):787-94. PubMed ID: 2339989
    [Abstract] [Full Text] [Related]

  • 9. Insulin receptor kinase domain autophosphorylation regulates receptor enzymatic function.
    Wilden PA, Kahn CR, Siddle K, White MF.
    J Biol Chem; 1992 Aug 15; 267(23):16660-8. PubMed ID: 1322912
    [Abstract] [Full Text] [Related]

  • 10. Genistein differentially inhibits postreceptor effects of insulin in rat adipocytes without inhibiting the insulin receptor kinase.
    Abler A, Smith JA, Randazzo PA, Rothenberg PL, Jarett L.
    J Biol Chem; 1992 Feb 25; 267(6):3946-51. PubMed ID: 1310987
    [Abstract] [Full Text] [Related]

  • 11. A 60-kilodalton protein in rat hepatoma cells overexpressing insulin receptor was tyrosine phosphorylated and associated with Syp, phophatidylinositol 3-kinase, and Grb2 in an insulin-dependent manner.
    Zhang-Sun G, Yang C, Viallet J, Feng G, Bergeron JJ, Posner BI.
    Endocrinology; 1996 Jul 25; 137(7):2649-58. PubMed ID: 8770882
    [Abstract] [Full Text] [Related]

  • 12. Coordinate phosphorylation of insulin-receptor kinase and its 175,000-Mr endogenous substrate in rat hepatocytes.
    Okamoto M, Karasik A, White MF, Kahn CR.
    Diabetes; 1991 Jan 25; 40(1):66-72. PubMed ID: 1849850
    [Abstract] [Full Text] [Related]

  • 13. Insulin and 12-O-tetradecanoylphorbol-13-acetate activation of two immunologically distinct myelin basic protein/microtubule-associated protein 2 (MBP/MAP2) kinases via de novo phosphorylation of threonine and tyrosine residues.
    Tobe K, Kadowaki T, Tamemoto H, Ueki K, Hara K, Koshio O, Momomura K, Gotoh Y, Nishida E, Akanuma Y.
    J Biol Chem; 1991 Dec 25; 266(36):24793-803. PubMed ID: 1662217
    [Abstract] [Full Text] [Related]

  • 14. Insulin stimulation of phosphatidylinositol 3-kinase activity maps to insulin receptor regions required for endogenous substrate phosphorylation.
    Backer JM, Schroeder GG, Kahn CR, Myers MG, Wilden PA, Cahill DA, White MF.
    J Biol Chem; 1992 Jan 15; 267(2):1367-74. PubMed ID: 1309768
    [Abstract] [Full Text] [Related]

  • 15. Autoantibodies to the insulin receptor (B-10) can stimulate tyrosine phosphorylation of the beta-subunit of the insulin receptor and a 185,000 molecular weight protein in rat hepatoma cells.
    Takayama-Hasumi S, Tobe K, Momomura K, Koshio O, Tashiro-Hashimoto Y, Akanuma Y, Hirata Y, Takaku F, Kasuga M.
    J Clin Endocrinol Metab; 1989 Apr 15; 68(4):787-95. PubMed ID: 2466044
    [Abstract] [Full Text] [Related]

  • 16. Identification of the insulin receptor tyrosine residues undergoing insulin-stimulated phosphorylation in intact rat hepatoma cells.
    Tornqvist HE, Gunsalus JR, Nemenoff RA, Frackelton AR, Pierce MW, Avruch J.
    J Biol Chem; 1988 Jan 05; 263(1):350-9. PubMed ID: 3275643
    [Abstract] [Full Text] [Related]

  • 17. Insulin-stimulated tyrosine phosphorylation of a 43 kDa protein in rat liver membranes.
    Klee U, Singh TJ.
    Mol Cell Biochem; 1991 Nov 13; 108(1):19-27. PubMed ID: 1722868
    [Abstract] [Full Text] [Related]

  • 18. Two-dimensional phosphopeptide analysis of the autophosphorylation cascade of a soluble insulin receptor tyrosine kinase. The tyrosines phosphorylated are typical of those observed following phosphorylation of the heterotetrameric insulin receptor in intact cells.
    Tavaré JM, Clack B, Ellis L.
    J Biol Chem; 1991 Jan 25; 266(3):1390-5. PubMed ID: 1703148
    [Abstract] [Full Text] [Related]

  • 19. Insulin-receptor tyrosine kinase and glucose transport.
    Lane MD, Flores-Riveros JR, Hresko RC, Kaestner KH, Liao K, Janicot M, Hoffman RD, McLenithan JC, Kastelic T, Christy RJ.
    Diabetes Care; 1990 Jun 25; 13(6):565-75. PubMed ID: 2162754
    [Abstract] [Full Text] [Related]

  • 20. Expression and function of IRS-1 in insulin signal transmission.
    Sun XJ, Miralpeix M, Myers MG, Glasheen EM, Backer JM, Kahn CR, White MF.
    J Biol Chem; 1992 Nov 05; 267(31):22662-72. PubMed ID: 1385403
    [Abstract] [Full Text] [Related]

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