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Journal Abstract Search

609 related items for PubMed ID: 20227434

  • 1. Anticonvulsant, anxiolytic, and non-sedating actions of imidazenil and other imidazo-benzodiazepine carboxamide derivatives.
    Auta J, Kadriu B, Giusti P, Costa E, Guidotti A.
    Pharmacol Biochem Behav; 2010 Jun; 95(4):383-9. PubMed ID: 20227434
    [Abstract] [Full Text] [Related]

  • 2. Imidazenil, a non-sedating anticonvulsant benzodiazepine, is more potent than diazepam in protecting against DFP-induced seizures and neuronal damage.
    Kadriu B, Guidotti A, Costa E, Auta J.
    Toxicology; 2009 Feb 27; 256(3):164-74. PubMed ID: 19111886
    [Abstract] [Full Text] [Related]

  • 3. Imidazenil: an antagonist of the sedative but not the anticonvulsant action of diazepam.
    Auta J, Costa E, Davis JM, Guidotti A.
    Neuropharmacology; 2005 Sep 27; 49(3):425-9. PubMed ID: 15964602
    [Abstract] [Full Text] [Related]

  • 4. Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.
    McKernan RM, Rosahl TW, Reynolds DS, Sur C, Wafford KA, Atack JR, Farrar S, Myers J, Cook G, Ferris P, Garrett L, Bristow L, Marshall G, Macaulay A, Brown N, Howell O, Moore KW, Carling RW, Street LJ, Castro JL, Ragan CI, Dawson GR, Whiting PJ.
    Nat Neurosci; 2000 Jun 27; 3(6):587-92. PubMed ID: 10816315
    [Abstract] [Full Text] [Related]

  • 5. Zolpidem, a novel nonbenzodiazepine hypnotic. I. Neuropharmacological and behavioral effects.
    Depoortere H, Zivkovic B, Lloyd KG, Sanger DJ, Perrault G, Langer SZ, Bartholini G.
    J Pharmacol Exp Ther; 1986 May 27; 237(2):649-58. PubMed ID: 2871178
    [Abstract] [Full Text] [Related]

  • 6. Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.
    Rudolph U, Crestani F, Benke D, Brünig I, Benson JA, Fritschy JM, Martin JR, Bluethmann H, Möhler H.
    Nature; 1999 Oct 21; 401(6755):796-800. PubMed ID: 10548105
    [Abstract] [Full Text] [Related]

  • 7. Differential contribution of GABA(A) receptor subtypes to the anticonvulsant efficacy of benzodiazepine site ligands.
    Fradley RL, Guscott MR, Bull S, Hallett DJ, Goodacre SC, Wafford KA, Garrett EM, Newman RJ, O'Meara GF, Whiting PJ, Rosahl TW, Dawson GR, Reynolds DS, Atack JR.
    J Psychopharmacol; 2007 Jun 21; 21(4):384-91. PubMed ID: 17092983
    [Abstract] [Full Text] [Related]

  • 8. The preferential antagonism of pentylenetetrazole proconflict responses differentiates a class of anxiolytic benzodiazepines with potential antipanic action.
    Giusti P, Guidetti G, Costa E, Guidotti A.
    J Pharmacol Exp Ther; 1991 Jun 21; 257(3):1062-8. PubMed ID: 1675286
    [Abstract] [Full Text] [Related]

  • 9. Imidazenil: a new partial positive allosteric modulator of gamma-aminobutyric acid (GABA) action at GABAA receptors.
    Giusti P, Ducić I, Puia G, Arban R, Walser A, Guidotti A, Costa E.
    J Pharmacol Exp Ther; 1993 Aug 21; 266(2):1018-28. PubMed ID: 8394902
    [Abstract] [Full Text] [Related]

  • 10. Imidazenil, a positive allosteric GABAA receptor modulator, inhibits the effects of cocaine on locomotor activity and extracellular dopamine in the nucleus accumbens shell without tolerance liability.
    Giorgetti M, Javaid JI, Davis JM, Costa E, Guidotti A, Appel SB, Brodie MS.
    J Pharmacol Exp Ther; 1998 Oct 21; 287(1):58-66. PubMed ID: 9765322
    [Abstract] [Full Text] [Related]

  • 11. Imidazenil: a low efficacy agonist at alpha1- but high efficacy at alpha5-GABAA receptors fail to show anticonvulsant cross tolerance to diazepam or zolpidem.
    Auta J, Impagnatiello F, Kadriu B, Guidotti A, Costa E.
    Neuropharmacology; 2008 Aug 21; 55(2):148-53. PubMed ID: 18555494
    [Abstract] [Full Text] [Related]

  • 12. 5-ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2a]pyridine-4-N-(2-fluorophenyl)carboxamide (RWJ-51204), a new nonbenzodiazepine anxiolytic.
    Dubinsky B, Vaidya AH, Rosenthal DI, Hochman C, Crooke JJ, DeLuca S, DeVine A, Cheo-Isaacs CT, Carter AR, Jordan AD, Reitz AB, Shank RP.
    J Pharmacol Exp Ther; 2002 Nov 21; 303(2):777-90. PubMed ID: 12388665
    [Abstract] [Full Text] [Related]

  • 13. SL651498: an anxioselective compound with functional selectivity for alpha2- and alpha3-containing gamma-aminobutyric acid(A) (GABA(A)) receptors.
    Griebel G, Perrault G, Simiand J, Cohen C, Granger P, Decobert M, Françon D, Avenet P, Depoortere H, Tan S, Oblin A, Schoemaker H, Evanno Y, Sevrin M, George P, Scatton B.
    J Pharmacol Exp Ther; 2001 Aug 21; 298(2):753-68. PubMed ID: 11454940
    [Abstract] [Full Text] [Related]

  • 14. Effects of acute and repeated zolpidem treatment on pentylenetetrazole-induced seizure threshold and on locomotor activity: comparison with diazepam.
    Vlainić J, Pericić D.
    Neuropharmacology; 2009 Jun 21; 56(8):1124-30. PubMed ID: 19345234
    [Abstract] [Full Text] [Related]

  • 15. The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors.
    Popik P, Kostakis E, Krawczyk M, Nowak G, Szewczyk B, Krieter P, Chen Z, Russek SJ, Gibbs TT, Farb DH, Skolnick P, Lippa AS, Basile AS.
    J Pharmacol Exp Ther; 2006 Dec 21; 319(3):1244-52. PubMed ID: 16971504
    [Abstract] [Full Text] [Related]

  • 16. GABA A receptor subtype selectivity underlying selective anxiolytic effect of baicalin.
    Wang F, Xu Z, Ren L, Tsang SY, Xue H.
    Neuropharmacology; 2008 Dec 21; 55(7):1231-7. PubMed ID: 18723037
    [Abstract] [Full Text] [Related]

  • 17. Acute imidazenil treatment after the onset of DFP-induced seizure is more effective and longer lasting than midazolam at preventing seizure activity and brain neuropathology.
    Kadriu B, Guidotti A, Costa E, Davis JM, Auta J.
    Toxicol Sci; 2011 Mar 21; 120(1):136-45. PubMed ID: 21097996
    [Abstract] [Full Text] [Related]

  • 18. N,N'-dicyclohexylsulfamide and N,N'-diphenethylsulfamide are anticonvulsant sulfamides with affinity for the benzodiazepine binding site of the GABA(A) receptor and anxiolytic activity in mice.
    Wasowski C, Gavernet L, Barrios IA, Villalba ML, Pastore V, Samaja G, Enrique A, Bruno-Blanch LE, Marder M.
    Biochem Pharmacol; 2012 Jan 15; 83(2):253-9. PubMed ID: 22056620
    [Abstract] [Full Text] [Related]

  • 19. gamma-Aminobutyric acidA receptor heterogeneity in rat central nervous system: studies with clonazepam and other benzodiazepine ligands.
    Massotti M, Schlichting JL, Antonacci MD, Giusti P, Memo M, Costa E, Guidotti A.
    J Pharmacol Exp Ther; 1991 Mar 15; 256(3):1154-60. PubMed ID: 1848629
    [Abstract] [Full Text] [Related]

  • 20. Native gamma-aminobutyric acid type A receptors from rat hippocampus, containing both alpha 1 and alpha 5 subunits, exhibit a single benzodiazepine binding site with alpha 5 pharmacological properties.
    Araujo F, Ruano D, Vitorica J.
    J Pharmacol Exp Ther; 1999 Sep 15; 290(3):989-97. PubMed ID: 10454469
    [Abstract] [Full Text] [Related]

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