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392 related items for PubMed ID: 20230062

  • 1. Development of a proteolytically stable retro-inverso peptide inhibitor of beta-amyloid oligomerization as a potential novel treatment for Alzheimer's disease.
    Taylor M, Moore S, Mayes J, Parkin E, Beeg M, Canovi M, Gobbi M, Mann DM, Allsop D.
    Biochemistry; 2010 Apr 20; 49(15):3261-72. PubMed ID: 20230062
    [Abstract] [Full Text] [Related]

  • 2. Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's beta-amyloid peptide.
    Austen BM, Paleologou KE, Ali SA, Qureshi MM, Allsop D, El-Agnaf OM.
    Biochemistry; 2008 Feb 19; 47(7):1984-92. PubMed ID: 18189413
    [Abstract] [Full Text] [Related]

  • 3. Development of retro-inverso peptides as anti-aggregation drugs for β-amyloid in Alzheimer's disease.
    Matharu B, El-Agnaf O, Razvi A, Austen BM.
    Peptides; 2010 Oct 19; 31(10):1866-72. PubMed ID: 20633587
    [Abstract] [Full Text] [Related]

  • 4. Peptide and protein mimetics inhibiting amyloid beta-peptide aggregation.
    Takahashi T, Mihara H.
    Acc Chem Res; 2008 Oct 19; 41(10):1309-18. PubMed ID: 18937396
    [Abstract] [Full Text] [Related]

  • 5. Engineered antibody intervention strategies for Alzheimer's disease and related dementias by targeting amyloid and toxic oligomers.
    Robert R, Dolezal O, Waddington L, Hattarki MK, Cappai R, Masters CL, Hudson PJ, Wark KL.
    Protein Eng Des Sel; 2009 Mar 19; 22(3):199-208. PubMed ID: 18927231
    [Abstract] [Full Text] [Related]

  • 6. Understanding the molecular basis for the inhibition of the Alzheimer's Abeta-peptide oligomerization by human serum albumin using saturation transfer difference and off-resonance relaxation NMR spectroscopy.
    Milojevic J, Esposito V, Das R, Melacini G.
    J Am Chem Soc; 2007 Apr 11; 129(14):4282-90. PubMed ID: 17367135
    [Abstract] [Full Text] [Related]

  • 7. Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease.
    Barghorn S, Nimmrich V, Striebinger A, Krantz C, Keller P, Janson B, Bahr M, Schmidt M, Bitner RS, Harlan J, Barlow E, Ebert U, Hillen H.
    J Neurochem; 2005 Nov 11; 95(3):834-47. PubMed ID: 16135089
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of cytotoxicity and amyloid fibril formation by a D-amino acid peptide that specifically binds to Alzheimer's disease amyloid peptide.
    Wiesehan K, Stöhr J, Nagel-Steger L, van Groen T, Riesner D, Willbold D.
    Protein Eng Des Sel; 2008 Apr 11; 21(4):241-6. PubMed ID: 18252750
    [Abstract] [Full Text] [Related]

  • 9. Rational design of amyloid beta peptide-binding proteins: pseudo-Abeta beta-sheet surface presented in green fluorescent protein binds tightly and preferentially to structured Abeta.
    Takahashi T, Ohta K, Mihara H.
    Proteins; 2010 Feb 01; 78(2):336-47. PubMed ID: 19731370
    [Abstract] [Full Text] [Related]

  • 10. Formation of highly toxic soluble amyloid beta oligomers by the molecular chaperone prefoldin.
    Sakono M, Zako T, Ueda H, Yohda M, Maeda M.
    FEBS J; 2008 Dec 01; 275(23):5982-93. PubMed ID: 19021772
    [Abstract] [Full Text] [Related]

  • 11. Protective effect of colostrinin on neuroblastoma cell survival is due to reduced aggregation of beta-amyloid.
    Schuster D, Rajendran A, Hui SW, Nicotera T, Srikrishnan T, Kruzel ML.
    Neuropeptides; 2005 Aug 01; 39(4):419-26. PubMed ID: 15890402
    [Abstract] [Full Text] [Related]

  • 12. Ellagic acid promotes Abeta42 fibrillization and inhibits Abeta42-induced neurotoxicity.
    Feng Y, Yang SG, Du XT, Zhang X, Sun XX, Zhao M, Sun GY, Liu RT.
    Biochem Biophys Res Commun; 2009 Dec 25; 390(4):1250-4. PubMed ID: 19878655
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological evaluation of clicked curcumin and clicked KLVFFA conjugates as inhibitors of beta-amyloid fibril formation.
    Ouberai M, Dumy P, Chierici S, Garcia J.
    Bioconjug Chem; 2009 Nov 25; 20(11):2123-32. PubMed ID: 19821579
    [Abstract] [Full Text] [Related]

  • 14. Oligomerization and toxicity of beta-amyloid-42 implicated in Alzheimer's disease.
    El-Agnaf OM, Mahil DS, Patel BP, Austen BM.
    Biochem Biophys Res Commun; 2000 Jul 14; 273(3):1003-7. PubMed ID: 10891362
    [Abstract] [Full Text] [Related]

  • 15. The N-methylated peptide SEN304 powerfully inhibits Aβ(1-42) toxicity by perturbing oligomer formation.
    Amijee H, Bate C, Williams A, Virdee J, Jeggo R, Spanswick D, Scopes DI, Treherne JM, Mazzitelli S, Chawner R, Eyers CE, Doig AJ.
    Biochemistry; 2012 Oct 23; 51(42):8338-52. PubMed ID: 23025847
    [Abstract] [Full Text] [Related]

  • 16. Ectoine and hydroxyectoine inhibit aggregation and neurotoxicity of Alzheimer's beta-amyloid.
    Kanapathipillai M, Lentzen G, Sierks M, Park CB.
    FEBS Lett; 2005 Aug 29; 579(21):4775-80. PubMed ID: 16098972
    [Abstract] [Full Text] [Related]

  • 17. Assembling amyloid fibrils from designed structures containing a significant amyloid beta-peptide fragment.
    Tjernberg LO, Tjernberg A, Bark N, Shi Y, Ruzsicska BP, Bu Z, Thyberg J, Callaway DJ.
    Biochem J; 2002 Aug 15; 366(Pt 1):343-51. PubMed ID: 12023906
    [Abstract] [Full Text] [Related]

  • 18. Single chain variable fragments against beta-amyloid (Abeta) can inhibit Abeta aggregation and prevent abeta-induced neurotoxicity.
    Liu R, Yuan B, Emadi S, Zameer A, Schulz P, McAllister C, Lyubchenko Y, Goud G, Sierks MR.
    Biochemistry; 2004 Jun 08; 43(22):6959-67. PubMed ID: 15170333
    [Abstract] [Full Text] [Related]

  • 19. Direct in vivo intracellular selection of conformation-sensitive antibody domains targeting Alzheimer's amyloid-beta oligomers.
    Meli G, Visintin M, Cannistraci I, Cattaneo A.
    J Mol Biol; 2009 Apr 03; 387(3):584-606. PubMed ID: 19361429
    [Abstract] [Full Text] [Related]

  • 20. Design of peptides that form amyloid-like fibrils capturing amyloid beta1-42 peptides.
    Sato J, Takahashi T, Oshima H, Matsumura S, Mihara H.
    Chemistry; 2007 Apr 03; 13(27):7745-52. PubMed ID: 17605154
    [Abstract] [Full Text] [Related]

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