These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

115 related items for PubMed ID: 2031249

  • 1. Relationship between covalent binding to microsomal protein and the destruction of adrenal cytochrome P-450 by spironolactone.
    Colby HD, O'Donnell JP, Flowers NL, Kossor DC, Johnson PB, Levitt M.
    Toxicology; 1991 Apr 08; 67(2):143-54. PubMed ID: 2031249
    [Abstract] [Full Text] [Related]

  • 2. Role of the steroid 17 alpha-hydroxylase in spironolactone-mediated destruction of adrenal cytochrome P-450.
    Kossor DC, Kominami S, Takemori S, Colby HD.
    Mol Pharmacol; 1991 Aug 08; 40(2):321-5. PubMed ID: 1875914
    [Abstract] [Full Text] [Related]

  • 3. Metabolism of spironolactone by adrenocortical and hepatic microsomes: relationship to cytochrome P-450 destruction.
    Sherry JH, O'Donnell JP, Flowers L, Lacagnin LB, Colby HD.
    J Pharmacol Exp Ther; 1986 Mar 08; 236(3):675-80. PubMed ID: 3950869
    [Abstract] [Full Text] [Related]

  • 4. Destruction of testicular cytochrome P-450 by 7 alpha-thiospironolactone is catalyzed by the 17 alpha-hydroxylase.
    Kossor DC, Kominami S, Takemori S, Colby HD.
    J Steroid Biochem Mol Biol; 1992 May 08; 42(3-4):421-4. PubMed ID: 1606053
    [Abstract] [Full Text] [Related]

  • 5. Adrenal mitochondrial metabolism of spironolactone. Absence of metabolic activation.
    Flowers NL, Sherry JH, O'Donnell JP, Colby HD.
    Biochem Pharmacol; 1988 Apr 15; 37(8):1591-5. PubMed ID: 3358788
    [Abstract] [Full Text] [Related]

  • 6. Spironolactone inhibition of cortisol production by guinea pig adrenocortical cells.
    Rourke KA, Colby HD.
    Horm Metab Res; 1990 Nov 15; 22(11):573-5. PubMed ID: 2177032
    [Abstract] [Full Text] [Related]

  • 7. Mechanism of action of spironolactone on cortisol production by guinea pig adrenocortical cells.
    Rourke KA, Bergstrom JM, Larson IW, Colby HD.
    Mol Cell Endocrinol; 1991 Oct 15; 81(1-3):127-34. PubMed ID: 1797582
    [Abstract] [Full Text] [Related]

  • 8. Stimulation of microsomal spironolactone metabolism by reduced glutathione.
    Colby HD, LaCagnin LB, Los LE.
    Pharmacology; 1996 Jan 15; 52(1):30-4. PubMed ID: 8966200
    [Abstract] [Full Text] [Related]

  • 9. Conversion of spironolactone to 7 alpha-thiomethylspironolactone by hepatic and renal microsomes.
    LaCagnin LB, Lutsie P, Colby HD.
    Biochem Pharmacol; 1987 Oct 15; 36(20):3439-44. PubMed ID: 3675606
    [Abstract] [Full Text] [Related]

  • 10. Conversion of spironolactone to an active metabolite in target tissues: formation of 7 alpha-thiospironolactone by microsomal preparations from guinea pig liver, adrenals, kidneys, and testes.
    Sherry JH, O'Donnell JP, Colby HD.
    Life Sci; 1981 Dec 28; 29(26):2727-36. PubMed ID: 7329203
    [No Abstract] [Full Text] [Related]

  • 11. Dose-dependent actions of spironolactone on the inner and outer zones of the guinea pig adrenal cortex.
    Kossor DC, Colby HD.
    Pharmacology; 1992 Dec 28; 45(1):27-33. PubMed ID: 1508965
    [Abstract] [Full Text] [Related]

  • 12.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 13.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 14.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 15. Studies on the destruction of adrenal and testicular cytochrome P-450 by spironolactone. Requirement for the 7alpha-thio group and evidence for the loss of the heme and apoproteins of cytochrome P-450.
    Menard RH, Guenthner TM, Kon H, Gillette JR.
    J Biol Chem; 1979 Mar 10; 254(5):1726-33. PubMed ID: 762169
    [No Abstract] [Full Text] [Related]

  • 16. Characterization of the NADPH-dependent covalent binding of [14C]halothane to human liver microsomes: a role for cytochrome P4502E1 at low substrate concentrations.
    Madan A, Parkinson A.
    Drug Metab Dispos; 1996 Dec 10; 24(12):1307-13. PubMed ID: 8971135
    [Abstract] [Full Text] [Related]

  • 17. Changes in adrenal microsomal cytochrome(s) P-450 with aging in the guinea pig.
    Colby HD, Rumbaugh RC, Stitzel RE.
    Endocrinology; 1980 Nov 10; 107(5):1359-63. PubMed ID: 6775926
    [Abstract] [Full Text] [Related]

  • 18. Metabolic activation of lidocaine and covalent binding to rat liver microsomal protein.
    Masubuchi Y, Araki J, Narimatsu S, Suzuki T.
    Biochem Pharmacol; 1992 Jun 23; 43(12):2551-7. PubMed ID: 1632813
    [Abstract] [Full Text] [Related]

  • 19. Mechanism of action of spironolactone on adrenocortical function in guinea pigs.
    Greiner JW, Kramer RE, Jarrell J, Colby HD.
    J Pharmacol Exp Ther; 1976 Sep 23; 198(3):709-15. PubMed ID: 978470
    [Abstract] [Full Text] [Related]

  • 20. Comparative effects of cadmium, zinc, and lead in vitro on pulmonary, adrenal, and hepatic microsomal metabolism in the guinea pig.
    Colby HD, Johnson PB, Zulkoski JS, Pope MR, Miles PR.
    J Toxicol Environ Health; 1981 Sep 23; 8(5-6):907-15. PubMed ID: 7338951
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 6.