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Journal Abstract Search

103 related items for PubMed ID: 20350808

  • 1. Bivalent 5,8,9,13b-tetrahydro-6H-isoquino[1,2-a]isoquinolines and -isoquinolinium salts: novel heterocyclic templates for butyrylcholinesterase inhibitors.
    Schulze M, Siol O, Decker M, Lehmann J.
    Bioorg Med Chem Lett; 2010 May 01; 20(9):2946-9. PubMed ID: 20350808
    [Abstract] [Full Text] [Related]

  • 2. Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic heads over affinity and selectivity.
    Conejo-García A, Pisani L, Núñez Mdel C, Catto M, Nicolotti O, Leonetti F, Campos JM, Gallo MA, Espinosa A, Carotti A.
    J Med Chem; 2011 Apr 28; 54(8):2627-45. PubMed ID: 21417225
    [Abstract] [Full Text] [Related]

  • 3. Preparation and in vitro screening of symmetrical bis-isoquinolinium cholinesterase inhibitors bearing various connecting linkage--implications for early Myasthenia gravis treatment.
    Musilek K, Komloova M, Holas O, Hrabinova M, Pohanka M, Dohnal V, Nachon F, Dolezal M, Kuca K.
    Eur J Med Chem; 2011 Feb 28; 46(2):811-8. PubMed ID: 21236521
    [Abstract] [Full Text] [Related]

  • 4. Homobivalent quinazolinimines as novel nanomolar inhibitors of cholinesterases with dirigible selectivity toward butyrylcholinesterase.
    Decker M.
    J Med Chem; 2006 Sep 07; 49(18):5411-3. PubMed ID: 16942014
    [Abstract] [Full Text] [Related]

  • 5. Novel heterobivalent tacrine derivatives as cholinesterase inhibitors with notable selectivity toward butyrylcholinesterase.
    Elsinghorst PW, Tanarro CM, Gütschow M.
    J Med Chem; 2006 Dec 14; 49(25):7540-4. PubMed ID: 17149883
    [Abstract] [Full Text] [Related]

  • 6. Derivatives of oxoisoaporphine alkaloids: a novel class of selective acetylcholinesterase inhibitors.
    Tang H, Ning FX, Wei YB, Huang SL, Huang ZS, Chan AS, Gu LQ.
    Bioorg Med Chem Lett; 2007 Jul 01; 17(13):3765-8. PubMed ID: 17451950
    [Abstract] [Full Text] [Related]

  • 7. Novel tricyclic quinazolinimines and related tetracyclic nitrogen bridgehead compounds as cholinesterase inhibitors with selectivity towards butyrylcholinesterase.
    Decker M, Krauth F, Lehmann J.
    Bioorg Med Chem; 2006 Mar 15; 14(6):1966-77. PubMed ID: 16289855
    [Abstract] [Full Text] [Related]

  • 8. Novel inhibitors of acetyl- and butyrylcholinesterase derived from the alkaloids dehydroevodiamine and rutaecarpine.
    Decker M.
    Eur J Med Chem; 2005 Mar 15; 40(3):305-13. PubMed ID: 15725500
    [Abstract] [Full Text] [Related]

  • 9. Synthesis of novel phosphorothioates and phosphorodithioates and their differential inhibition of cholinesterases.
    Kaboudin B, Emadi S, Hadizadeh A.
    Bioorg Chem; 2009 Aug 15; 37(4):101-5. PubMed ID: 19481235
    [Abstract] [Full Text] [Related]

  • 10. Probing the mid-gorge of cholinesterases with spacer-modified bivalent quinazolinimines leads to highly potent and selective butyrylcholinesterase inhibitors.
    Chen X, Tikhonova IG, Decker M.
    Bioorg Med Chem; 2011 Feb 01; 19(3):1222-35. PubMed ID: 21232964
    [Abstract] [Full Text] [Related]

  • 11. Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors.
    Leonetti F, Catto M, Nicolotti O, Pisani L, Cappa A, Stefanachi A, Carotti A.
    Bioorg Med Chem; 2008 Aug 01; 16(15):7450-6. PubMed ID: 18585045
    [Abstract] [Full Text] [Related]

  • 12. Synthesis of 4-[(diethylamino)methyl]-phenol derivatives as novel cholinesterase inhibitors with selectivity towards butyrylcholinesterase.
    Yu L, Cao R, Yi W, Yan Q, Chen Z, Ma L, Peng W, Song H.
    Bioorg Med Chem Lett; 2010 Jun 01; 20(11):3254-8. PubMed ID: 20452769
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis and pharmacological evaluation of hybrid molecules out of quinazolinimines and lipoic acid lead to highly potent and selective butyrylcholinesterase inhibitors with antioxidant properties.
    Decker M, Kraus B, Heilmann J.
    Bioorg Med Chem; 2008 Apr 15; 16(8):4252-61. PubMed ID: 18343673
    [Abstract] [Full Text] [Related]

  • 14. Bis-(-)-nor-meptazinols as novel nanomolar cholinesterase inhibitors with high inhibitory potency on amyloid-beta aggregation.
    Xie Q, Wang H, Xia Z, Lu M, Zhang W, Wang X, Fu W, Tang Y, Sheng W, Li W, Zhou W, Zhu X, Qiu Z, Chen H.
    J Med Chem; 2008 Apr 10; 51(7):2027-36. PubMed ID: 18333606
    [Abstract] [Full Text] [Related]

  • 15. Synthesis of physostigmine analogues and evaluation of their anticholinesterase activities.
    Zhan ZJ, Bian HL, Wang JW, Shan WG.
    Bioorg Med Chem Lett; 2010 Mar 01; 20(5):1532-4. PubMed ID: 20144867
    [Abstract] [Full Text] [Related]

  • 16. Preparation and in vitro screening of symmetrical bispyridinium cholinesterase inhibitors bearing different connecting linkage-initial study for Myasthenia gravis implications.
    Musilek K, Komloova M, Zavadova V, Holas O, Hrabinova M, Pohanka M, Dohnal V, Nachon F, Dolezal M, Kuca K, Jung YS.
    Bioorg Med Chem Lett; 2010 Mar 01; 20(5):1763-6. PubMed ID: 20138518
    [Abstract] [Full Text] [Related]

  • 17. Synthesis of novel phenserine-based-selective inhibitors of butyrylcholinesterase for Alzheimer's disease.
    Yu Q, Holloway HW, Utsuki T, Brossi A, Greig NH.
    J Med Chem; 1999 May 20; 42(10):1855-61. PubMed ID: 10346939
    [Abstract] [Full Text] [Related]

  • 18. Synthesis, Analysis, Cholinesterase-Inhibiting Activity and Molecular Modelling Studies of 3-(Dialkylamino)-2-hydroxypropyl 4-[(Alkoxy-carbonyl)amino]benzoates and Their Quaternary Ammonium Salts.
    Padrtova T, Marvanova P, Odehnalova K, Kubinova R, Parravicini O, Garro A, Enriz RD, Humpa O, Oravec M, Mokry P.
    Molecules; 2017 Nov 23; 22(12):. PubMed ID: 29168793
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues.
    Bolognesi ML, Bartolini M, Cavalli A, Andrisano V, Rosini M, Minarini A, Melchiorre C.
    J Med Chem; 2004 Nov 18; 47(24):5945-52. PubMed ID: 15537349
    [Abstract] [Full Text] [Related]

  • 20. Synthesis, biological evaluation and molecular modelling of diversely functionalized heterocyclic derivatives as inhibitors of acetylcholinesterase/butyrylcholinesterase and modulators of Ca2+ channels and nicotinic receptors.
    Marco JL, de los Ríos C, García AG, Villarroya M, Carreiras MC, Martins C, Eleutério A, Morreale A, Orozco M, Luque FJ.
    Bioorg Med Chem; 2004 May 01; 12(9):2199-218. PubMed ID: 15080920
    [Abstract] [Full Text] [Related]

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