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406 related items for PubMed ID: 20354156

  • 1. LKB1 deletion with the RIP2.Cre transgene modifies pancreatic beta-cell morphology and enhances insulin secretion in vivo.
    Sun G, Tarasov AI, McGinty JA, French PM, McDonald A, Leclerc I, Rutter GA.
    Am J Physiol Endocrinol Metab; 2010 Jun; 298(6):E1261-73. PubMed ID: 20354156
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  • 2. Ablation of AMP-activated protein kinase alpha1 and alpha2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo.
    Sun G, Tarasov AI, McGinty J, McDonald A, da Silva Xavier G, Gorman T, Marley A, French PM, Parker H, Gribble F, Reimann F, Prendiville O, Carzaniga R, Viollet B, Leclerc I, Rutter GA.
    Diabetologia; 2010 May; 53(5):924-36. PubMed ID: 20221584
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  • 3. Transcription factor-7-like 2 (TCF7L2) gene acts downstream of the Lkb1/Stk11 kinase to control mTOR signaling, β cell growth, and insulin secretion.
    Nguyen-Tu MS, da Silva Xavier G, Leclerc I, Rutter GA.
    J Biol Chem; 2018 Sep 07; 293(36):14178-14189. PubMed ID: 29967064
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  • 5. Loss of Lkb1 in adult beta cells increases beta cell mass and enhances glucose tolerance in mice.
    Fu A, Ng AC, Depatie C, Wijesekara N, He Y, Wang GS, Bardeesy N, Scott FW, Touyz RM, Wheeler MB, Screaton RA.
    Cell Metab; 2009 Oct 07; 10(4):285-95. PubMed ID: 19808021
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  • 6. LKB1 and AMPK differentially regulate pancreatic β-cell identity.
    Kone M, Pullen TJ, Sun G, Ibberson M, Martinez-Sanchez A, Sayers S, Nguyen-Tu MS, Kantor C, Swisa A, Dor Y, Gorman T, Ferrer J, Thorens B, Reimann F, Gribble F, McGinty JA, Chen L, French PM, Birzele F, Hildebrandt T, Uphues I, Rutter GA.
    FASEB J; 2014 Nov 07; 28(11):4972-85. PubMed ID: 25070369
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  • 9. Deletion of Lkb1 in pro-opiomelanocortin neurons impairs peripheral glucose homeostasis in mice.
    Claret M, Smith MA, Knauf C, Al-Qassab H, Woods A, Heslegrave A, Piipari K, Emmanuel JJ, Colom A, Valet P, Cani PD, Begum G, White A, Mucket P, Peters M, Mizuno K, Batterham RL, Giese KP, Ashworth A, Burcelin R, Ashford ML, Carling D, Withers DJ.
    Diabetes; 2011 Mar 07; 60(3):735-45. PubMed ID: 21266325
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  • 12. Augmentation of insulin secretion by leucine supplementation in malnourished rats: possible involvement of the phosphatidylinositol 3-phosphate kinase/mammalian target protein of rapamycin pathway.
    Filiputti E, Rafacho A, Araújo EP, Silveira LR, Trevisan A, Batista TM, Curi R, Velloso LA, Quesada I, Boschero AC, Carneiro EM.
    Metabolism; 2010 May 07; 59(5):635-44. PubMed ID: 19913855
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  • 15. AMPK and Friends: Central Regulators of β Cell Biology.
    Rourke JL, Hu Q, Screaton RA.
    Trends Endocrinol Metab; 2018 Feb 07; 29(2):111-122. PubMed ID: 29289437
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  • 16. Inhibition of β-Catenin Activity Abolishes LKB1 Loss-Driven Pancreatic Cystadenoma in Mice.
    Hsieh MJ, Weng CC, Lin YC, Wu CC, Chen LT, Cheng KH.
    Int J Mol Sci; 2021 Apr 28; 22(9):. PubMed ID: 33924999
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  • 17. RIP2-mediated LKB1 deletion causes axon degeneration in the spinal cord and hind-limb paralysis.
    Sun G, Reynolds R, Leclerc I, Rutter GA.
    Dis Model Mech; 2011 Mar 28; 4(2):193-202. PubMed ID: 21135058
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  • 18. LKB1 regulates pancreatic beta cell size, polarity, and function.
    Granot Z, Swisa A, Magenheim J, Stolovich-Rain M, Fujimoto W, Manduchi E, Miki T, Lennerz JK, Stoeckert CJ, Meyuhas O, Seino S, Permutt MA, Piwnica-Worms H, Bardeesy N, Dor Y.
    Cell Metab; 2009 Oct 28; 10(4):296-308. PubMed ID: 19808022
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  • 19. Marked phenotypic differences of endurance performance and exercise-induced oxygen consumption between AMPK and LKB1 deficiency in mouse skeletal muscle: changes occurring in the diaphragm.
    Miura S, Kai Y, Tadaishi M, Tokutake Y, Sakamoto K, Bruce CR, Febbraio MA, Kita K, Chohnan S, Ezaki O.
    Am J Physiol Endocrinol Metab; 2013 Jul 15; 305(2):E213-29. PubMed ID: 23695215
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  • 20. Deletion of Protein Kinase D1 in Pancreatic β-Cells Impairs Insulin Secretion in High-Fat Diet-Fed Mice.
    Bergeron V, Ghislain J, Vivot K, Tamarina N, Philipson LH, Fielitz J, Poitout V.
    Diabetes; 2018 Jan 15; 67(1):71-77. PubMed ID: 29038309
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