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Journal Abstract Search


196 related items for PubMed ID: 20360004

  • 1. Scaffold proteins IRSp53 and spinophilin regulate localized Rac activation by T-lymphocyte invasion and metastasis protein 1 (TIAM1).
    Rajagopal S, Ji Y, Xu K, Li Y, Wicks K, Liu J, Wong KW, Herman IM, Isberg RR, Buchsbaum RJ.
    J Biol Chem; 2010 Jun 04; 285(23):18060-71. PubMed ID: 20360004
    [Abstract] [Full Text] [Related]

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  • 3. Tiam1-IRSp53 complex formation directs specificity of rac-mediated actin cytoskeleton regulation.
    Connolly BA, Rice J, Feig LA, Buchsbaum RJ.
    Mol Cell Biol; 2005 Jun 04; 25(11):4602-14. PubMed ID: 15899863
    [Abstract] [Full Text] [Related]

  • 4. Interaction between Tiam1 and the Arp2/3 complex links activation of Rac to actin polymerization.
    Ten Klooster JP, Evers EE, Janssen L, Machesky LM, Michiels F, Hordijk P, Collard JG.
    Biochem J; 2006 Jul 01; 397(1):39-45. PubMed ID: 16599904
    [Abstract] [Full Text] [Related]

  • 5. Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1.
    Van Leeuwen FN, Olivo C, Grivell S, Giepmans BN, Collard JG, Moolenaar WH.
    J Biol Chem; 2003 Jan 03; 278(1):400-6. PubMed ID: 12393875
    [Abstract] [Full Text] [Related]

  • 6. IRSp53/Eps8 complex is important for positive regulation of Rac and cancer cell motility/invasiveness.
    Funato Y, Terabayashi T, Suenaga N, Seiki M, Takenawa T, Miki H.
    Cancer Res; 2004 Aug 01; 64(15):5237-44. PubMed ID: 15289329
    [Abstract] [Full Text] [Related]

  • 7. Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior.
    Sander EE, ten Klooster JP, van Delft S, van der Kammen RA, Collard JG.
    J Cell Biol; 1999 Nov 29; 147(5):1009-22. PubMed ID: 10579721
    [Abstract] [Full Text] [Related]

  • 8. The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.
    Leeuwen FN, Kain HE, Kammen RA, Michiels F, Kranenburg OW, Collard JG.
    J Cell Biol; 1997 Nov 03; 139(3):797-807. PubMed ID: 9348295
    [Abstract] [Full Text] [Related]

  • 9. The Rac exchange factor Tiam1 is required for the establishment and maintenance of cadherin-based adhesions.
    Malliri A, van Es S, Huveneers S, Collard JG.
    J Biol Chem; 2004 Jul 16; 279(29):30092-8. PubMed ID: 15138270
    [Abstract] [Full Text] [Related]

  • 10. Regulation of breast cancer cell motility by T-cell lymphoma invasion and metastasis-inducing protein.
    Adams HC, Chen R, Liu Z, Whitehead IP.
    Breast Cancer Res; 2010 Jul 16; 12(5):R69. PubMed ID: 20819206
    [Abstract] [Full Text] [Related]

  • 11. Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation.
    Michiels F, Stam JC, Hordijk PL, van der Kammen RA, Ruuls-Van Stalle L, Feltkamp CA, Collard JG.
    J Cell Biol; 1997 Apr 21; 137(2):387-98. PubMed ID: 9128250
    [Abstract] [Full Text] [Related]

  • 12. Hepatocyte growth factor triggers distinct mechanisms of Asef and Tiam1 activation to induce endothelial barrier enhancement.
    Higginbotham K, Tian Y, Gawlak G, Moldobaeva N, Shah A, Birukova AA.
    Cell Signal; 2014 Nov 21; 26(11):2306-16. PubMed ID: 25101856
    [Abstract] [Full Text] [Related]

  • 13. The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling.
    Boissier P, Huynh-Do U.
    Cell Signal; 2014 Mar 21; 26(3):483-91. PubMed ID: 24308970
    [Abstract] [Full Text] [Related]

  • 14. Rac is a dominant regulator of cadherin-directed actin assembly that is activated by adhesive ligation independently of Tiam1.
    Kraemer A, Goodwin M, Verma S, Yap AS, Ali RG.
    Am J Physiol Cell Physiol; 2007 Mar 21; 292(3):C1061-9. PubMed ID: 17020937
    [Abstract] [Full Text] [Related]

  • 15. High-resolution structure of the Tiam1 PHn-CC-Ex domain.
    Joshi M, Gakhar L, Fuentes EJ.
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2013 Jul 21; 69(Pt 7):744-52. PubMed ID: 23832200
    [Abstract] [Full Text] [Related]

  • 16. Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression.
    Engers R, Springer E, Michiels F, Collard JG, Gabbert HE.
    J Biol Chem; 2001 Nov 09; 276(45):41889-97. PubMed ID: 11551917
    [Abstract] [Full Text] [Related]

  • 17. The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migration.
    Saxena M, Dykes SS, Malyarchuk S, Wang AE, Cardelli JA, Pruitt K.
    Oncogene; 2015 Jan 08; 34(2):188-98. PubMed ID: 24362520
    [Abstract] [Full Text] [Related]

  • 18. HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion.
    Vaughan L, Tan CT, Chapman A, Nonaka D, Mack NA, Smith D, Booton R, Hurlstone AF, Malliri A.
    Cell Rep; 2015 Jan 06; 10(1):88-102. PubMed ID: 25543140
    [Abstract] [Full Text] [Related]

  • 19. HGF attenuates thrombin-induced endothelial permeability by Tiam1-mediated activation of the Rac pathway and by Tiam1/Rac-dependent inhibition of the Rho pathway.
    Birukova AA, Alekseeva E, Mikaelyan A, Birukov KG.
    FASEB J; 2007 Sep 06; 21(11):2776-86. PubMed ID: 17428964
    [Abstract] [Full Text] [Related]

  • 20. IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling.
    Miki H, Yamaguchi H, Suetsugu S, Takenawa T.
    Nature; 2000 Dec 07; 408(6813):732-5. PubMed ID: 11130076
    [Abstract] [Full Text] [Related]


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