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367 related items for PubMed ID: 20371721

  • 1. Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3.
    Yang F, Brown C, Buettner R, Hedvat M, Starr R, Scuto A, Schroeder A, Jensen M, Jove R.
    Mol Cancer Ther; 2010 Apr; 9(4):953-62. PubMed ID: 20371721
    [Abstract] [Full Text] [Related]

  • 2. Sorafenib inhibits endogenous and IL-6/S1P induced JAK2-STAT3 signaling in human neuroblastoma, associated with growth suppression and apoptosis.
    Yang F, Jove V, Buettner R, Xin H, Wu J, Wang Y, Nam S, Xu Y, Ara T, DeClerck YA, Seeger R, Yu H, Jove R.
    Cancer Biol Ther; 2012 May; 13(7):534-41. PubMed ID: 22406995
    [Abstract] [Full Text] [Related]

  • 3. Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas.
    Yang F, Van Meter TE, Buettner R, Hedvat M, Liang W, Kowolik CM, Mepani N, Mirosevich J, Nam S, Chen MY, Tye G, Kirschbaum M, Jove R.
    Mol Cancer Ther; 2008 Nov; 7(11):3519-26. PubMed ID: 19001435
    [Abstract] [Full Text] [Related]

  • 4. Sorafenib induces apoptosis in HL60 cells by inhibiting Src kinase-mediated STAT3 phosphorylation.
    Zhao W, Zhang T, Qu B, Wu X, Zhu X, Meng F, Gu Y, Shu Y, Shen Y, Sun Y, Xu Q.
    Anticancer Drugs; 2011 Jan; 22(1):79-88. PubMed ID: 20881478
    [Abstract] [Full Text] [Related]

  • 5. Sorafenib induces growth inhibition and apoptosis in human synovial sarcoma cells via inhibiting the RAF/MEK/ERK signaling pathway.
    Peng CL, Guo W, Ji T, Ren T, Yang Y, Li DS, Qu HY, Li X, Tang S, Yan TQ, Tang XD.
    Cancer Biol Ther; 2009 Sep; 8(18):1729-36. PubMed ID: 19633425
    [Abstract] [Full Text] [Related]

  • 6. Sorafenib inhibits STAT3 activation to enhance TRAIL-mediated apoptosis in human pancreatic cancer cells.
    Huang S, Sinicrope FA.
    Mol Cancer Ther; 2010 Mar; 9(3):742-50. PubMed ID: 20197401
    [Abstract] [Full Text] [Related]

  • 7. Sorafenib inhibits growth and metastasis of hepatocellular carcinoma by blocking STAT3.
    Gu FM, Li QL, Gao Q, Jiang JH, Huang XY, Pan JF, Fan J, Zhou J.
    World J Gastroenterol; 2011 Sep 14; 17(34):3922-32. PubMed ID: 22025881
    [Abstract] [Full Text] [Related]

  • 8. Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures.
    Carra E, Barbieri F, Marubbi D, Pattarozzi A, Favoni RE, Florio T, Daga A.
    Cell Cycle; 2013 Feb 01; 12(3):491-500. PubMed ID: 23324350
    [Abstract] [Full Text] [Related]

  • 9. Sorafenib triggers antiproliferative and pro-apoptotic signals in human esophageal adenocarcinoma cells.
    Delgado JS, Mustafi R, Yee J, Cerda S, Chumsangsri A, Dougherty U, Lichtenstein L, Fichera A, Bissonnette M.
    Dig Dis Sci; 2008 Dec 01; 53(12):3055-64. PubMed ID: 18512153
    [Abstract] [Full Text] [Related]

  • 10. Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2.
    Blechacz BR, Smoot RL, Bronk SF, Werneburg NW, Sirica AE, Gores GJ.
    Hepatology; 2009 Dec 01; 50(6):1861-70. PubMed ID: 19821497
    [Abstract] [Full Text] [Related]

  • 11. The farnesyl transferase inhibitor lonafarnib inhibits mTOR signaling and enforces sorafenib-induced apoptosis in melanoma cells.
    Niessner H, Beck D, Sinnberg T, Lasithiotakis K, Maczey E, Gogel J, Venturelli S, Berger A, Mauthe M, Toulany M, Flaherty K, Schaller M, Schadendorf D, Proikas-Cezanne T, Schittek B, Garbe C, Kulms D, Meier F.
    J Invest Dermatol; 2011 Feb 01; 131(2):468-79. PubMed ID: 20944654
    [Abstract] [Full Text] [Related]

  • 12. Sorafenib-induced apoptosis of chronic lymphocytic leukemia cells is associated with downregulation of RAF and myeloid cell leukemia sequence 1 (Mcl-1).
    Fecteau JF, Bharati IS, O'Hayre M, Handel TM, Kipps TJ, Messmer D.
    Mol Med; 2012 Feb 10; 18(1):19-28. PubMed ID: 21979753
    [Abstract] [Full Text] [Related]

  • 13. Sorafenib decreases proliferation and induces apoptosis of prostate cancer cells by inhibition of the androgen receptor and Akt signaling pathways.
    Oh SJ, Erb HH, Hobisch A, Santer FR, Culig Z.
    Endocr Relat Cancer; 2012 Jun 10; 19(3):305-19. PubMed ID: 22383427
    [Abstract] [Full Text] [Related]

  • 14. Targeting of distinct signaling cascades and cancer-associated fibroblasts define the efficacy of Sorafenib against prostate cancer cells.
    Kharaziha P, Rodriguez P, Li Q, Rundqvist H, Björklund AC, Augsten M, Ullén A, Egevad L, Wiklund P, Nilsson S, Kroemer G, Grander D, Panaretakis T.
    Cell Death Dis; 2012 Jan 26; 3(1):e262. PubMed ID: 22278289
    [Abstract] [Full Text] [Related]

  • 15. Sorafenib downregulates ERK/Akt and STAT3 survival pathways and induces apoptosis in a human neuroblastoma cell line.
    Chai H, Luo AZ, Weerasinghe P, Brown RE.
    Int J Clin Exp Pathol; 2010 Apr 23; 3(4):408-15. PubMed ID: 20490331
    [Abstract] [Full Text] [Related]

  • 16. Sorafenib inhibits growth and mitogen-activated protein kinase signaling in malignant peripheral nerve sheath cells.
    Ambrosini G, Cheema HS, Seelman S, Teed A, Sambol EB, Singer S, Schwartz GK.
    Mol Cancer Ther; 2008 Apr 23; 7(4):890-6. PubMed ID: 18413802
    [Abstract] [Full Text] [Related]

  • 17. Sunitinib induces apoptosis and growth arrest of medulloblastoma tumor cells by inhibiting STAT3 and AKT signaling pathways.
    Yang F, Jove V, Xin H, Hedvat M, Van Meter TE, Yu H.
    Mol Cancer Res; 2010 Jan 23; 8(1):35-45. PubMed ID: 20053726
    [Abstract] [Full Text] [Related]

  • 18. Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma.
    Tai WT, Cheng AL, Shiau CW, Huang HP, Huang JW, Chen PJ, Chen KF.
    J Hepatol; 2011 Nov 23; 55(5):1041-8. PubMed ID: 21354226
    [Abstract] [Full Text] [Related]

  • 19. E804 induces growth arrest, differentiation and apoptosis of glioblastoma cells by blocking Stat3 signaling.
    Zhang Y, Du Z, Zhuang Z, Wang Y, Wang F, Liu S, Wang H, Feng H, Li H, Wang L, Zhang X, Hao A.
    J Neurooncol; 2015 Nov 23; 125(2):265-75. PubMed ID: 26386687
    [Abstract] [Full Text] [Related]

  • 20. Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells.
    Liu CY, Tseng LM, Su JC, Chang KC, Chu PY, Tai WT, Shiau CW, Chen KF.
    Breast Cancer Res; 2013 Nov 23; 15(4):R63. PubMed ID: 23938089
    [Abstract] [Full Text] [Related]

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