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Journal Abstract Search

589 related items for PubMed ID: 20378717

  • 1. Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.
    Tan SM, Li F, Rajendran P, Kumar AP, Hui KM, Sethi G.
    J Pharmacol Exp Ther; 2010 Jul; 334(1):285-93. PubMed ID: 20378717
    [Abstract] [Full Text] [Related]

  • 2. Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1.
    Rajendran P, Li F, Shanmugam MK, Vali S, Abbasi T, Kapoor S, Ahn KS, Kumar AP, Sethi G.
    J Cell Physiol; 2012 May; 227(5):2184-95. PubMed ID: 21792937
    [Abstract] [Full Text] [Related]

  • 3. Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells.
    Li F, Fernandez PP, Rajendran P, Hui KM, Sethi G.
    Cancer Lett; 2010 Jun 28; 292(2):197-207. PubMed ID: 20053498
    [Abstract] [Full Text] [Related]

  • 4. Janus activated kinase 2/signal transducer and activator of transcription 3 pathway mediates icariside II-induced apoptosis in U266 multiple myeloma cells.
    Kim SH, Ahn KS, Jeong SJ, Kwon TR, Jung JH, Yun SM, Han I, Lee SG, Kim DK, Kang M, Chen CY, Lee JW, Kim SH.
    Eur J Pharmacol; 2011 Mar 01; 654(1):10-6. PubMed ID: 21172343
    [Abstract] [Full Text] [Related]

  • 5. Embelin suppresses STAT3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase PTEN.
    Heo JY, Kim HJ, Kim SM, Park KR, Park SY, Kim SW, Nam D, Jang HJ, Lee SG, Ahn KS, Kim SH, Shim BS, Choi SH, Ahn KS.
    Cancer Lett; 2011 Sep 01; 308(1):71-80. PubMed ID: 21565443
    [Abstract] [Full Text] [Related]

  • 6. Decursin chemosensitizes human multiple myeloma cells through inhibition of STAT3 signaling pathway.
    Kim HJ, Kim SM, Park KR, Jang HJ, Na YS, Ahn KS, Kim SH, Ahn KS.
    Cancer Lett; 2011 Feb 01; 301(1):29-37. PubMed ID: 21122982
    [Abstract] [Full Text] [Related]

  • 7. γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent.
    Rajendran P, Li F, Manu KA, Shanmugam MK, Loo SY, Kumar AP, Sethi G.
    Br J Pharmacol; 2011 May 01; 163(2):283-98. PubMed ID: 21198544
    [Abstract] [Full Text] [Related]

  • 8. Concomitant inactivation of the epidermal growth factor receptor, phosphatidylinositol 3-kinase/Akt and Janus tyrosine kinase 2/signal transducer and activator of transcription 3 signalling pathways in cardiotoxin III-treated A549 cells.
    Su JC, Lin KL, Chien CM, Chuang PW, Chang LS, Lin SR.
    Clin Exp Pharmacol Physiol; 2010 Aug 01; 37(8):833-40. PubMed ID: 20456425
    [Abstract] [Full Text] [Related]

  • 9. Nitidine chloride inhibits hepatocellular carcinoma cell growth in vivo through the suppression of the JAK1/STAT3 signaling pathway.
    Liao J, Xu T, Zheng JX, Lin JM, Cai QY, Yu DB, Peng J.
    Int J Mol Med; 2013 Jul 01; 32(1):79-84. PubMed ID: 23613111
    [Abstract] [Full Text] [Related]

  • 10. Ursolic acid inhibits STAT3 activation pathway leading to suppression of proliferation and chemosensitization of human multiple myeloma cells.
    Pathak AK, Bhutani M, Nair AS, Ahn KS, Chakraborty A, Kadara H, Guha S, Sethi G, Aggarwal BB.
    Mol Cancer Res; 2007 Sep 01; 5(9):943-55. PubMed ID: 17855663
    [Abstract] [Full Text] [Related]

  • 11. β-Caryophyllene oxide inhibits constitutive and inducible STAT3 signaling pathway through induction of the SHP-1 protein tyrosine phosphatase.
    Kim C, Cho SK, Kapoor S, Kumar A, Vali S, Abbasi T, Kim SH, Sethi G, Ahn KS.
    Mol Carcinog; 2014 Oct 01; 53(10):793-806. PubMed ID: 23765383
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of growth and metastasis of human hepatocellular carcinoma by antisense oligonucleotide targeting signal transducer and activator of transcription 3.
    Li WC, Ye SL, Sun RX, Liu YK, Tang ZY, Kim Y, Karras JG, Zhang H.
    Clin Cancer Res; 2006 Dec 01; 12(23):7140-8. PubMed ID: 17145839
    [Abstract] [Full Text] [Related]

  • 13. β-Escin sodium inhibits inducible nitric oxide synthase expression via downregulation of the JAK/STAT pathway in A549 cells.
    Ji DB, Xu B, Liu JT, Ran FX, Cui JR.
    Mol Carcinog; 2011 Dec 01; 50(12):945-60. PubMed ID: 21400616
    [Abstract] [Full Text] [Related]

  • 14. Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway.
    Li F, Rajendran P, Sethi G.
    Br J Pharmacol; 2010 Oct 01; 161(3):541-54. PubMed ID: 20880395
    [Abstract] [Full Text] [Related]

  • 15. Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse model.
    Shanmugam MK, Rajendran P, Li F, Kim C, Sikka S, Siveen KS, Kumar AP, Ahn KS, Sethi G.
    Mol Carcinog; 2015 Oct 01; 54(10):971-85. PubMed ID: 24797723
    [Abstract] [Full Text] [Related]

  • 16. Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells.
    Yang J, Cai X, Lu W, Hu C, Xu X, Yu Q, Cao P.
    Cancer Lett; 2013 Jan 28; 328(2):243-51. PubMed ID: 23032719
    [Abstract] [Full Text] [Related]

  • 17. Dovitinib sensitizes hepatocellular carcinoma cells to TRAIL and tigatuzumab, a novel anti-DR5 antibody, through SHP-1-dependent inhibition of STAT3.
    Chen KF, Chen HL, Liu CY, Tai WT, Ichikawa K, Chen PJ, Cheng AL.
    Biochem Pharmacol; 2012 Mar 15; 83(6):769-77. PubMed ID: 22230479
    [Abstract] [Full Text] [Related]

  • 18. GYY4137, a hydrogen sulfide (H₂S) donor, shows potent anti-hepatocellular carcinoma activity through blocking the STAT3 pathway.
    Lu S, Gao Y, Huang X, Wang X.
    Int J Oncol; 2014 Apr 15; 44(4):1259-67. PubMed ID: 24535538
    [Abstract] [Full Text] [Related]

  • 19. Abrogation of constitutive STAT3 activity sensitizes human hepatoma cells to TRAIL-mediated apoptosis.
    Kusaba M, Nakao K, Goto T, Nishimura D, Kawashimo H, Shibata H, Motoyoshi Y, Taura N, Ichikawa T, Hamasaki K, Eguchi K.
    J Hepatol; 2007 Oct 15; 47(4):546-55. PubMed ID: 17602782
    [Abstract] [Full Text] [Related]

  • 20. Capillarisin inhibits constitutive and inducible STAT3 activation through induction of SHP-1 and SHP-2 tyrosine phosphatases.
    Lee JH, Chiang SY, Nam D, Chung WS, Lee J, Na YS, Sethi G, Ahn KS.
    Cancer Lett; 2014 Apr 01; 345(1):140-8. PubMed ID: 24333736
    [Abstract] [Full Text] [Related]

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