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Journal Abstract Search

493 related items for PubMed ID: 20391594

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  • 23. Identification and quantification of glutathione adducts of clozapine using ultra-high-performance liquid chromatography with orthogonal acceleration time-of-flight mass spectrometry and inductively coupled plasma mass spectrometry.
    MacDonald C, Smith C, Michopoulos F, Weaver R, Wilson ID.
    Rapid Commun Mass Spectrom; 2011 Jul 15; 25(13):1787-93. PubMed ID: 21638353
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  • 25. Prediction of in vivo potential for metabolic activation of drugs into chemically reactive intermediate: correlation of in vitro and in vivo generation of reactive intermediates and in vitro glutathione conjugate formation in rats and humans.
    Masubuchi N, Makino C, Murayama N.
    Chem Res Toxicol; 2007 Mar 15; 20(3):455-64. PubMed ID: 17309281
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  • 27. Atrazine metabolite screening in human microsomes: detection of novel reactive metabolites and glutathione adducts by LC-MS.
    LeBlanc A, Sleno L.
    Chem Res Toxicol; 2011 Mar 21; 24(3):329-39. PubMed ID: 21361395
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  • 28. Characterization of a highly sensitive and selective novel trapping reagent, stable isotope labeled glutathione ethyl ester, for the detection of reactive metabolites.
    Yamaoka T, Kitamura Y.
    J Pharmacol Toxicol Methods; 2015 Mar 21; 76():83-95. PubMed ID: 26314789
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  • 29. An algorithm for thorough background subtraction from high-resolution LC/MS data: application for detection of glutathione-trapped reactive metabolites.
    Zhang H, Yang Y.
    J Mass Spectrom; 2008 Sep 21; 43(9):1181-90. PubMed ID: 18300330
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  • 30. Detoxification of cytotoxic alpha,beta-unsaturated aldehydes by carnosine: characterization of conjugated adducts by electrospray ionization tandem mass spectrometry and detection by liquid chromatography/mass spectrometry in rat skeletal muscle.
    Aldini G, Granata P, Carini M.
    J Mass Spectrom; 2002 Dec 21; 37(12):1219-28. PubMed ID: 12489081
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  • 31. The development of a higher throughput reactive intermediate screening assay incorporating micro-bore liquid chromatography-micro-electrospray ionization-tandem mass spectrometry and glutathione ethyl ester as an in vitro conjugating agent.
    Soglia JR, Harriman SP, Zhao S, Barberia J, Cole MJ, Boyd JG, Contillo LG.
    J Pharm Biomed Anal; 2004 Sep 21; 36(1):105-16. PubMed ID: 15351054
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  • 32. Bioactivation of coumarin in rat olfactory mucosal microsomes: Detection of protein covalent binding and identification of reactive intermediates through analysis of glutathione adducts.
    Zhuo X, Zhao W, Zheng J, Humphreys WG, Shu YZ, Zhu M.
    Chem Biol Interact; 2009 Oct 07; 181(2):227-35. PubMed ID: 19576871
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  • 35. High-throughput screening and characterization of reactive metabolites using polarity switching of hybrid triple quadrupole linear ion trap mass spectrometry.
    Wen B, Ma L, Nelson SD, Zhu M.
    Anal Chem; 2008 Mar 01; 80(5):1788-99. PubMed ID: 18251522
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  • 36. Cyanide trapping of iminium ion reactive intermediates followed by detection and structure identification using liquid chromatography-tandem mass spectrometry (LC-MS/MS).
    Argoti D, Liang L, Conteh A, Chen L, Bershas D, Yu CP, Vouros P, Yang E.
    Chem Res Toxicol; 2005 Oct 01; 18(10):1537-44. PubMed ID: 16533017
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  • 39. A ferrocene-based reagent for the conjugation and quantification of reactive metabolites.
    Jahn S, Lohmann W, Bomke S, Baumann A, Karst U.
    Anal Bioanal Chem; 2012 Jan 01; 402(1):461-71. PubMed ID: 21931954
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  • 40. Determining protein adducts of fipexide: mass spectrometry based assay for confirming the involvement of its reactive metabolite in covalent binding.
    Sleno L, Varesio E, Hopfgartner G.
    Rapid Commun Mass Spectrom; 2007 Jan 01; 21(24):4149-57. PubMed ID: 18022964
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