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Journal Abstract Search

156 related items for PubMed ID: 2040029

  • 1. Melphalan-induced toxicity in nude mice following pretreatment with buthionine sulfoximine.
    Skapek SX, VanDellen AF, McMahon DP, Postels DG, Griffith OW, Bigner DD, Friedman HS.
    Cancer Chemother Pharmacol; 1991; 28(1):15-21. PubMed ID: 2040029
    [Abstract] [Full Text] [Related]

  • 2. Enhancement of melphalan-induced gastrointestinal toxicity in mice treated with regional hyperthermia and BSO-mediated glutathione depletion.
    Laskowitz DT, Elion GB, Dewhirst MW, Griffith OW, Cattley RC, Bigner DD, Friedman HS.
    Int J Hyperthermia; 1992; 8(1):111-20. PubMed ID: 1545157
    [Abstract] [Full Text] [Related]

  • 3. Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione.
    Ozols RF, Louie KG, Plowman J, Behrens BC, Fine RL, Dykes D, Hamilton TC.
    Biochem Pharmacol; 1987 Jan 01; 36(1):147-53. PubMed ID: 3801051
    [Abstract] [Full Text] [Related]

  • 4. In vivo modulation of glutathione by buthionine sulfoximine: effect on marrow response to melphalan.
    Russo A, Tochner Z, Phillips T, Carmichael J, DeGraff W, Friedman N, Fisher J, Mitchell JB.
    Int J Radiat Oncol Biol Phys; 1986 Jul 01; 12(7):1187-9. PubMed ID: 3744938
    [Abstract] [Full Text] [Related]

  • 5. Phase I trial of buthionine sulfoximine in combination with melphalan in patients with cancer.
    O'Dwyer PJ, Hamilton TC, LaCreta FP, Gallo JM, Kilpatrick D, Halbherr T, Brennan J, Bookman MA, Hoffman J, Young RC, Comis RL, Ozols RF.
    J Clin Oncol; 1996 Jan 01; 14(1):249-56. PubMed ID: 8558205
    [Abstract] [Full Text] [Related]

  • 6. Enhanced melphalan cytotoxicity following buthionine sulfoximine-mediated glutathione depletion in a human medulloblastoma xenograft in athymic mice.
    Skapek SX, Colvin OM, Griffith OW, Elion GB, Bigner DD, Friedman HS.
    Cancer Res; 1988 May 15; 48(10):2764-7. PubMed ID: 3359437
    [Abstract] [Full Text] [Related]

  • 7. In vivo therapeutic potential of combination thiol depletion and alkylating chemotherapy.
    Siemann DW, Beyers KL.
    Br J Cancer; 1993 Dec 15; 68(6):1071-9. PubMed ID: 8260357
    [Abstract] [Full Text] [Related]

  • 8. Pharmacokinetics of buthionine sulfoximine (NSC 326231) and its effect on melphalan-induced toxicity in mice.
    Smith AC, Liao JT, Page JG, Wientjes MG, Grieshaber CK.
    Cancer Res; 1989 Oct 01; 49(19):5385-91. PubMed ID: 2766304
    [Abstract] [Full Text] [Related]

  • 9. Chemosensitization of L-phenylalanine mustard by the thiol-modulating agent buthionine sulfoximine.
    Kramer RA, Greene K, Ahmad S, Vistica DT.
    Cancer Res; 1987 Mar 15; 47(6):1593-7. PubMed ID: 3815359
    [Abstract] [Full Text] [Related]

  • 10. Phase I clinical trial of intravenous L-buthionine sulfoximine and melphalan: an attempt at modulation of glutathione.
    Bailey HH, Mulcahy RT, Tutsch KD, Arzoomanian RZ, Alberti D, Tombes MB, Wilding G, Pomplun M, Spriggs DR.
    J Clin Oncol; 1994 Jan 15; 12(1):194-205. PubMed ID: 8270977
    [Abstract] [Full Text] [Related]

  • 11. Increased melphalan activity in intracranial human medulloblastoma and glioma xenografts following buthionine sulfoximine-mediated glutathione depletion.
    Friedman HS, Colvin OM, Griffith OW, Lippitz B, Elion GB, Schold SC, Hilton J, Bigner DD.
    J Natl Cancer Inst; 1989 Apr 05; 81(7):524-7. PubMed ID: 2921776
    [Abstract] [Full Text] [Related]

  • 12. Phase I study of continuous-infusion L-S,R-buthionine sulfoximine with intravenous melphalan.
    Bailey HH, Ripple G, Tutsch KD, Arzoomanian RZ, Alberti D, Feierabend C, Mahvi D, Schink J, Pomplun M, Mulcahy RT, Wilding G.
    J Natl Cancer Inst; 1997 Dec 03; 89(23):1789-96. PubMed ID: 9392620
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of the acute toxicity of methyl chloride in male B6C3F1 mice by glutathione depletion.
    Chellman GJ, White RD, Norton RM, Bus JS.
    Toxicol Appl Pharmacol; 1986 Oct 03; 86(1):93-104. PubMed ID: 3764938
    [Abstract] [Full Text] [Related]

  • 14. Establishment of a melphalan-resistant rhabdomyosarcoma xenograft with cross-resistance to vincristine and enhanced sensitivity following buthionine sulfoximine-mediated glutathione depletion.
    Rosenberg MC, Colvin OM, Griffith OW, Bigner SH, Elion GB, Horton JK, Lilley E, Bigner DD, Friedman HS.
    Cancer Res; 1989 Dec 15; 49(24 Pt 1):6917-22. PubMed ID: 2582434
    [Abstract] [Full Text] [Related]

  • 15. The effect of glutathione depletion by buthionine sulphoximine on 1-cyano-3,4-epithiobutane toxicity.
    VanSteenhouse JL, Fettman MJ, Gould DH.
    Food Chem Toxicol; 1991 Mar 15; 29(3):153-7. PubMed ID: 2032656
    [Abstract] [Full Text] [Related]

  • 16. Effect of D,L-buthionine-S,R-sulfoximine on cytotoxicity and DNA cross-linking induced by bifunctional DNA-reactive cytostatic drugs in human melanoma cells.
    Hansson J, Edgren M, Ehrsson H, Ringborg U, Nilsson B.
    Cancer Res; 1988 Jan 01; 48(1):19-26. PubMed ID: 3334994
    [Abstract] [Full Text] [Related]

  • 17. Induction of rat UDP-glucuronosyltransferase and glutathione S-transferase activities by L-buthionine-S,R-sulfoximine without induction of cytochrome P-450.
    Manning BW, Franklin MR.
    Toxicology; 1990 Dec 17; 65(1-2):149-59. PubMed ID: 2125759
    [Abstract] [Full Text] [Related]

  • 18. Cytotoxic effects of glutathione synthesis inhibition by L-buthionine-(SR)-sulfoximine on human and murine tumor cells.
    Dorr RT, Liddil JD, Soble MJ.
    Invest New Drugs; 1986 Dec 17; 4(4):305-13. PubMed ID: 3583642
    [Abstract] [Full Text] [Related]

  • 19. Time-dependent pharmacodynamic models in cancer chemotherapy: population pharmacodynamic model for glutathione depletion following modulation by buthionine sulfoximine (BSO) in a Phase I trial of melphalan and BSO.
    Gallo JM, Brennan J, Hamilton TC, Halbherr T, Laub PB, Ozols RF, O'Dwyer PJ.
    Cancer Res; 1995 Oct 15; 55(20):4507-11. PubMed ID: 7553617
    [Abstract] [Full Text] [Related]

  • 20. Enhancement of antitumor activity of cisplatin on human gastric cancer cells in vitro and in vivo by buthionine sulfoximine.
    Saikawa Y, Kubota T, Kuo TH, Furukawa T, Tanino H, Watanabe M, Ishibiki K, Kitajima M.
    Jpn J Cancer Res; 1993 Jul 15; 84(7):787-93. PubMed ID: 8370654
    [Abstract] [Full Text] [Related]

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