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Journal Abstract Search

154 related items for PubMed ID: 20402561

  • 21. Cytochromes P450 and drug discovery.
    Lamb DC, Waterman MR, Kelly SL, Guengerich FP.
    Curr Opin Biotechnol; 2007 Dec; 18(6):504-12. PubMed ID: 18006294
    [Abstract] [Full Text] [Related]

  • 22. Predicting drug metabolism: a site of metabolism prediction tool applied to the cytochrome P450 2C9.
    Zamora I, Afzelius L, Cruciani G.
    J Med Chem; 2003 Jun 05; 46(12):2313-24. PubMed ID: 12773036
    [Abstract] [Full Text] [Related]

  • 23. The complexities inherent in attempts to decrease drug clearance by blocking sites of CYP-mediated metabolism.
    Fisher MB, Henne KR, Boer J.
    Curr Opin Drug Discov Devel; 2006 Jan 05; 9(1):101-9. PubMed ID: 16445122
    [Abstract] [Full Text] [Related]

  • 24. Electrochemically driven drug metabolism by membranes containing human cytochrome P450.
    Mie Y, Suzuki M, Komatsu Y.
    J Am Chem Soc; 2009 May 20; 131(19):6646-7. PubMed ID: 19402636
    [Abstract] [Full Text] [Related]

  • 25. High confidence predictions of drug-drug interactions: predicting affinities for cytochrome P450 2C9 with multiple computational methods.
    Hudelson MG, Ketkar NS, Holder LB, Carlson TJ, Peng CC, Waldher BJ, Jones JP.
    J Med Chem; 2008 Feb 14; 51(3):648-54. PubMed ID: 18211009
    [Abstract] [Full Text] [Related]

  • 26. [Cytochromes P450: xenobiotic metabolism, regulation and clinical importance].
    Guéguen Y, Mouzat K, Ferrari L, Tissandie E, Lobaccaro JM, Batt AM, Paquet F, Voisin P, Aigueperse J, Gourmelon P, Souidi M.
    Ann Biol Clin (Paris); 2006 Feb 14; 64(6):535-48. PubMed ID: 17162257
    [Abstract] [Full Text] [Related]

  • 27. In vitro-in vivo scaling of CYP kinetic data not consistent with the classical Michaelis-Menten model.
    Houston JB, Kenworthy KE.
    Drug Metab Dispos; 2000 Mar 14; 28(3):246-54. PubMed ID: 10681367
    [Abstract] [Full Text] [Related]

  • 28. Assessment of cytochrome P450 fluorometric substrates with rainbow trout and killifish exposed to dexamethasone, pregnenolone-16alpha-carbonitrile, rifampicin, and beta-naphthoflavone.
    Smith EM, Wilson JY.
    Aquat Toxicol; 2010 May 10; 97(4):324-33. PubMed ID: 20167382
    [Abstract] [Full Text] [Related]

  • 29. New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme.
    Wang B, Yang LP, Zhang XZ, Huang SQ, Bartlam M, Zhou SF.
    Drug Metab Rev; 2009 May 10; 41(4):573-643. PubMed ID: 19645588
    [Abstract] [Full Text] [Related]

  • 30. Novel hierarchical classification and visualization method for multiobjective optimization of drug properties: application to structure-activity relationship analysis of cytochrome P450 metabolism.
    Yamashita F, Hara H, Ito T, Hashida M.
    J Chem Inf Model; 2008 Feb 10; 48(2):364-9. PubMed ID: 18211048
    [Abstract] [Full Text] [Related]

  • 31. Prediction of drug-like molecular properties: modeling cytochrome p450 interactions.
    Jalaie M, Arimoto R, Gifford E, Schefzick S, Waller CL.
    Methods Mol Biol; 2004 Feb 10; 275():449-520. PubMed ID: 15141126
    [Abstract] [Full Text] [Related]

  • 32. Chemical proteomic tool for ligand mapping of CYP antitargets: an NMR-compatible 3D QSAR descriptor in the Heme-Based Coordinate System.
    Yao H, Costache AD, Sem DS.
    J Chem Inf Comput Sci; 2004 Feb 10; 44(4):1456-65. PubMed ID: 15272854
    [Abstract] [Full Text] [Related]

  • 33. Prediction of cytochrome P450 mediated metabolism.
    Olsen L, Oostenbrink C, Jørgensen FS.
    Adv Drug Deliv Rev; 2015 Jun 23; 86():61-71. PubMed ID: 25958010
    [Abstract] [Full Text] [Related]

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  • 35. Accumulation and metabolism of drugs and CYP probe substrates in zebrafish larvae.
    Alderton W, Berghmans S, Butler P, Chassaing H, Fleming A, Golder Z, Richards F, Gardner I.
    Xenobiotica; 2010 Aug 23; 40(8):547-57. PubMed ID: 20528625
    [Abstract] [Full Text] [Related]

  • 36. Insights into drug metabolism by cytochromes P450 from modelling studies of CYP2D6-drug interactions.
    Maréchal JD, Kemp CA, Roberts GC, Paine MJ, Wolf CR, Sutcliffe MJ.
    Br J Pharmacol; 2008 Mar 23; 153 Suppl 1(Suppl 1):S82-9. PubMed ID: 18026129
    [Abstract] [Full Text] [Related]

  • 37. Substrate SARs in human P450s.
    Lewis DF, Dickins M.
    Drug Discov Today; 2002 Sep 01; 7(17):918-25. PubMed ID: 12546935
    [Abstract] [Full Text] [Related]

  • 38. Computational methods and tools to predict cytochrome P450 metabolism for drug discovery.
    Tyzack JD, Kirchmair J.
    Chem Biol Drug Des; 2019 Apr 01; 93(4):377-386. PubMed ID: 30471192
    [Abstract] [Full Text] [Related]

  • 39. Cytochrome P450s: mechanisms and biological implications in drug metabolism and its interaction with oxidative stress.
    Bhattacharyya S, Sinha K, Sil PC.
    Curr Drug Metab; 2014 Apr 01; 15(7):719-42. PubMed ID: 25429675
    [Abstract] [Full Text] [Related]

  • 40. Structural insights into understudied human cytochrome P450 enzymes.
    Machalz D, Pach S, Bermudez M, Bureik M, Wolber G.
    Drug Discov Today; 2021 Oct 01; 26(10):2456-2464. PubMed ID: 34161845
    [Abstract] [Full Text] [Related]

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