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Journal Abstract Search

830 related items for PubMed ID: 20427474

  • 1. DBM1285 suppresses tumor necrosis factor alpha production by blocking p38 mitogen-activated protein kinase/mitogen-activated protein kinase-activated protein kinase 2 signaling pathway.
    Kang JS, Kim HM, Choi IY, Han SB, Yoon YD, Lee H, Park KH, Cho IJ, Lee CW, Lee K, Lee KH, Park SK.
    J Pharmacol Exp Ther; 2010 Aug; 334(2):657-64. PubMed ID: 20427474
    [Abstract] [Full Text] [Related]

  • 2. TRIF signaling stimulates translation of TNF-alpha mRNA via prolonged activation of MK2.
    Gais P, Tiedje C, Altmayr F, Gaestel M, Weighardt H, Holzmann B.
    J Immunol; 2010 May 15; 184(10):5842-8. PubMed ID: 20375303
    [Abstract] [Full Text] [Related]

  • 3. Anti-inflammatory properties of a novel N-phenyl pyridinone inhibitor of p38 mitogen-activated protein kinase: preclinical-to-clinical translation.
    Hope HR, Anderson GD, Burnette BL, Compton RP, Devraj RV, Hirsch JL, Keith RH, Li X, Mbalaviele G, Messing DM, Saabye MJ, Schindler JF, Selness SR, Stillwell LI, Webb EG, Zhang J, Monahan JB.
    J Pharmacol Exp Ther; 2009 Dec 15; 331(3):882-95. PubMed ID: 19720877
    [Abstract] [Full Text] [Related]

  • 4. KR-003048, a potent, orally active inhibitor of p38 mitogen-activated protein kinase.
    Montalban AG, Boman E, Chang CD, Ceide SC, Dahl R, Dalesandro D, Delaet NG, Erb E, Ernst J, Gibbs A, Kahl J, Kessler L, Lundström J, Miller S, Nakanishi H, Roberts E, Saiah E, Sullivan R, Wang Z, Larson CJ.
    Eur J Pharmacol; 2010 Apr 25; 632(1-3):93-102. PubMed ID: 20132813
    [Abstract] [Full Text] [Related]

  • 5. Regulation of monocyte IL-10 synthesis by endogenous IL-1 and TNF-alpha: role of the p38 and p42/44 mitogen-activated protein kinases.
    Foey AD, Parry SL, Williams LM, Feldmann M, Foxwell BM, Brennan FM.
    J Immunol; 1998 Jan 15; 160(2):920-8. PubMed ID: 9551930
    [Abstract] [Full Text] [Related]

  • 6. Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element.
    Hitti E, Iakovleva T, Brook M, Deppenmeier S, Gruber AD, Radzioch D, Clark AR, Blackshear PJ, Kotlyarov A, Gaestel M.
    Mol Cell Biol; 2006 Mar 15; 26(6):2399-407. PubMed ID: 16508014
    [Abstract] [Full Text] [Related]

  • 7. Pharmacological profile of AW-814141, a novel, potent, selective and orally active inhibitor of p38 MAP kinase.
    Chopra P, Kulkarni O, Gupta S, Bajpai M, Kanoje V, Banerjee M, Bansal V, Visaga S, Chatterjee M, Chaira T, Shirumalla RK, Verma AK, Dastidar SG, Sharma G, Ray A.
    Int Immunopharmacol; 2010 Apr 15; 10(4):467-73. PubMed ID: 20093202
    [Abstract] [Full Text] [Related]

  • 8. Sodium salicylate inhibits macrophage TNF-alpha production and alters MAPK activation.
    Vittimberga FJ, McDade TP, Perugini RA, Callery MP.
    J Surg Res; 1999 Jun 15; 84(2):143-9. PubMed ID: 10357911
    [Abstract] [Full Text] [Related]

  • 9. Roflumilast inhibits lipopolysaccharide-induced inflammatory mediators via suppression of nuclear factor-kappaB, p38 mitogen-activated protein kinase, and c-Jun NH2-terminal kinase activation.
    Kwak HJ, Song JS, Heo JY, Yang SD, Nam JY, Cheon HG.
    J Pharmacol Exp Ther; 2005 Dec 15; 315(3):1188-95. PubMed ID: 16126838
    [Abstract] [Full Text] [Related]

  • 10. Strong inhibition of TNF-alpha production and inhibition of IL-8 and COX-2 mRNA expression in monocyte-derived macrophages by RWJ 67657, a p38 mitogen-activated protein kinase (MAPK) inhibitor.
    Westra J, Doornbos-van der Meer B, de Boer P, van Leeuwen MA, van Rijswijk MH, Limburg PC.
    Arthritis Res Ther; 2004 Dec 15; 6(4):R384-92. PubMed ID: 15225374
    [Abstract] [Full Text] [Related]

  • 11. Dipyridamole activation of mitogen-activated protein kinase phosphatase-1 mediates inhibition of lipopolysaccharide-induced cyclooxygenase-2 expression in RAW 264.7 cells.
    Chen TH, Kao YC, Chen BC, Chen CH, Chan P, Lee HM.
    Eur J Pharmacol; 2006 Jul 17; 541(3):138-46. PubMed ID: 16765938
    [Abstract] [Full Text] [Related]

  • 12. Fragile X-related protein FXR1 controls post-transcriptional suppression of lipopolysaccharide-induced tumour necrosis factor-alpha production by transforming growth factor-beta1.
    Khera TK, Dick AD, Nicholson LB.
    FEBS J; 2010 Jul 17; 277(13):2754-65. PubMed ID: 20491901
    [Abstract] [Full Text] [Related]

  • 13. Suppression of lipopolysaccharide-induced cytokine production of gingival fibroblasts by a soybean, Kunitz trypsin inhibitor.
    Kobayashi H, Yoshida R, Kanada Y, Fukuda Y, Yagyu T, Inagaki K, Kondo T, Kurita N, Suzuki M, Kanayama N, Terao T.
    J Periodontal Res; 2005 Dec 17; 40(6):461-8. PubMed ID: 16302924
    [Abstract] [Full Text] [Related]

  • 14. Pamapimod, a novel p38 mitogen-activated protein kinase inhibitor: preclinical analysis of efficacy and selectivity.
    Hill RJ, Dabbagh K, Phippard D, Li C, Suttmann RT, Welch M, Papp E, Song KW, Chang KC, Leaffer D, Kim YN, Roberts RT, Zabka TS, Aud D, Dal Porto J, Manning AM, Peng SL, Goldstein DM, Wong BR.
    J Pharmacol Exp Ther; 2008 Dec 17; 327(3):610-9. PubMed ID: 18776065
    [Abstract] [Full Text] [Related]

  • 15. Activation of p38 MAPK is a key step in tumor necrosis factor-mediated inflammatory bone destruction.
    Zwerina J, Hayer S, Redlich K, Bobacz K, Kollias G, Smolen JS, Schett G.
    Arthritis Rheum; 2006 Feb 17; 54(2):463-72. PubMed ID: 16447221
    [Abstract] [Full Text] [Related]

  • 16. LPS-induced up-regulation of TGF-beta receptor 1 is associated with TNF-alpha expression in human monocyte-derived macrophages.
    Chen Y, Kam CS, Liu FQ, Liu Y, Lui VC, Lamb JR, Tam PK.
    J Leukoc Biol; 2008 May 17; 83(5):1165-73. PubMed ID: 18252868
    [Abstract] [Full Text] [Related]

  • 17. Distinct role of MAPKAPK-2 in the regulation of TNF gene expression by Toll-like receptor 7 and 9 ligands.
    Thuraisingam T, Xu YZ, Moisan J, Lachance C, Garnon J, Di Marco S, Gaestel M, Radzioch D.
    Mol Immunol; 2007 Jul 17; 44(14):3482-91. PubMed ID: 17485113
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of p38 mitogen-activated protein kinase prevents inflammatory bone destruction.
    Mbalaviele G, Anderson G, Jones A, De Ciechi P, Settle S, Mnich S, Thiede M, Abu-Amer Y, Portanova J, Monahan J.
    J Pharmacol Exp Ther; 2006 Jun 17; 317(3):1044-53. PubMed ID: 16501068
    [Abstract] [Full Text] [Related]

  • 19. MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis.
    Kotlyarov A, Neininger A, Schubert C, Eckert R, Birchmeier C, Volk HD, Gaestel M.
    Nat Cell Biol; 1999 Jun 17; 1(2):94-7. PubMed ID: 10559880
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  • 20. Flower extract of Panax notoginseng attenuates lipopolysaccharide-induced inflammatory response via blocking of NF-kappaB signaling pathway in murine macrophages.
    Jung HW, Seo UK, Kim JH, Leem KH, Park YK.
    J Ethnopharmacol; 2009 Mar 18; 122(2):313-9. PubMed ID: 19162159
    [Abstract] [Full Text] [Related]

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