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Journal Abstract Search

166 related items for PubMed ID: 20427476

  • 1. A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
    Neumann S, Huang W, Eliseeva E, Titus S, Thomas CJ, Gershengorn MC.
    Endocrinology; 2010 Jul; 151(7):3454-9. PubMed ID: 20427476
    [Abstract] [Full Text] [Related]

  • 2. A new small-molecule antagonist inhibits Graves' disease antibody activation of the TSH receptor.
    Neumann S, Eliseeva E, McCoy JG, Napolitano G, Giuliani C, Monaco F, Huang W, Gershengorn MC.
    J Clin Endocrinol Metab; 2011 Feb; 96(2):548-54. PubMed ID: 21123444
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  • 3. Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice.
    Neumann S, Huang W, Titus S, Krause G, Kleinau G, Alberobello AT, Zheng W, Southall NT, Inglese J, Austin CP, Celi FS, Gavrilova O, Thomas CJ, Raaka BM, Gershengorn MC.
    Proc Natl Acad Sci U S A; 2009 Jul 28; 106(30):12471-6. PubMed ID: 19592511
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  • 4. Small-molecule thyrotropin receptor agonist activates naturally occurring thyrotropin-insensitive mutants and reveals their distinct cyclic adenosine monophosphate signal persistence.
    Allen MD, Neumann S, Gershengorn MC.
    Thyroid; 2011 Aug 28; 21(8):907-12. PubMed ID: 21745101
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  • 7. Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro.
    Neumann S, Eliseeva E, Boutin A, Barnaeva E, Ferrer M, Southall N, Kim D, Hu X, Morgan SJ, Marugan JJ, Gershengorn MC.
    J Pharmacol Exp Ther; 2018 Jan 28; 364(1):38-45. PubMed ID: 29089368
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  • 8. Mutations in the mouse TSH receptor equivalent to human constitutively activating TSH receptor mutations also cause constitutive activity.
    Neumann S, Krohn K, Chey S, Paschke R.
    Horm Metab Res; 2001 May 28; 33(5):263-9. PubMed ID: 11440271
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  • 10. Persistent cAMP signaling by TSH receptors revealed by phosphodiesterase inhibition.
    Geras-Raaka E, Neumann S, Gershengorn MC.
    Thyroid; 2013 Nov 28; 23(11):1484-9. PubMed ID: 23713896
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  • 11. A human monoclonal autoantibody to the thyrotropin receptor with thyroid-stimulating blocking activity.
    Sanders J, Evans M, Betterle C, Sanders P, Bhardwaja A, Young S, Roberts E, Wilmot J, Richards T, Kiddie A, Small K, Platt H, Summerhayes S, Harris R, Reeve M, Coco G, Zanchetta R, Chen S, Furmaniak J, Smith BR.
    Thyroid; 2008 Jul 28; 18(7):735-46. PubMed ID: 18631002
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  • 12. TSH Receptor Homodimerization in Regulation of cAMP Production in Human Thyrocytes in vitro.
    Boutin A, Krieger CC, Marcus-Samuels B, Klubo-Gwiezdzinska J, Neumann S, Gershengorn MC.
    Front Endocrinol (Lausanne); 2020 Jul 28; 11():276. PubMed ID: 32425890
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  • 13. TSH receptor monoclonal antibodies with agonist, antagonist, and inverse agonist activities.
    Sanders J, Miguel RN, Furmaniak J, Smith BR.
    Methods Enzymol; 2010 Jul 28; 485():393-420. PubMed ID: 21050929
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  • 14. A Gq Biased Small Molecule Active at the TSH Receptor.
    Latif R, Morshed SA, Ma R, Tokat B, Mezei M, Davies TF.
    Front Endocrinol (Lausanne); 2020 Jul 28; 11():372. PubMed ID: 32676053
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  • 15. Persistent cAMP signaling by thyrotropin (TSH) receptors is not dependent on internalization.
    Neumann S, Geras-Raaka E, Marcus-Samuels B, Gershengorn MC.
    FASEB J; 2010 Oct 28; 24(10):3992-9. PubMed ID: 20538910
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  • 17. Substitutions of different regions of the third cytoplasmic loop of the thyrotropin (TSH) receptor have selective effects on constitutive, TSH-, and TSH receptor autoantibody-stimulated phosphoinositide and 3',5'-cyclic adenosine monophosphate signal generation.
    Kosugi S, Okajima F, Ban T, Hidaka A, Shenker A, Kohn LD.
    Mol Endocrinol; 1993 Aug 28; 7(8):1009-20. PubMed ID: 7901757
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  • 18. Characterization of thyrotropin receptor antibody-induced signaling cascades.
    Morshed SA, Latif R, Davies TF.
    Endocrinology; 2009 Jan 28; 150(1):519-29. PubMed ID: 18719020
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  • 19. New small molecule agonists to the thyrotropin receptor.
    Latif R, Ali MR, Ma R, David M, Morshed SA, Ohlmeyer M, Felsenfeld DP, Lau Z, Mezei M, Davies TF.
    Thyroid; 2015 Jan 28; 25(1):51-62. PubMed ID: 25333622
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  • 20. Thyrotropin (TSH) receptor antibodies (TSHrAb) can inhibit TSH-mediated cyclic adenosine 3',5'- monophosphate production in thyroid cells by either blocking TSH binding or affecting a step subsequent to TSH binding.
    Dallas JS, Cunningham SJ, Patibandla SA, Seetharamaiah GS, Morris JC, Tahara K, Kohn LD, Prabhakar BS.
    Endocrinology; 1996 Aug 28; 137(8):3329-39. PubMed ID: 8754759
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