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Journal Abstract Search

104 related items for PubMed ID: 20441176

  • 1. Conformationally constrained kappa receptor agonists: stereoselective synthesis and pharmacological evaluation of 6,8-diazabicyclo[3.2.2]nonane derivatives.
    Geiger C, Zelenka C, Lehmkuhl K, Schepmann D, Englberger W, Wünsch B.
    J Med Chem; 2010 May 27; 53(10):4212-22. PubMed ID: 20441176
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  • 2. Synthesis of 7,9-diazabicyclo[4.2.2]decanes as conformationally restricted κ receptor agonists: fine tuning of the dihedral angle of the ethylenediamine pharmacophore.
    Sunnam SK, Rack E, Schepmann D, Wünsch B.
    Eur J Med Chem; 2011 Jun 27; 46(6):1972-82. PubMed ID: 21481987
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  • 7. Methylated analogues of methyl (R)-4-(3,4-dichlorophenylacetyl)- 3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate (GR-89,696) as highly potent kappa-receptor agonists: stereoselective synthesis, opioid-receptor affinity, receptor selectivity, and functional studies.
    Soukara S, Maier CA, Predoiu U, Ehret A, Jackisch R, Wünsch B.
    J Med Chem; 2001 Aug 16; 44(17):2814-26. PubMed ID: 11495592
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  • 8. Synthesis and pharmacological evaluation of SNC80 analogues with a bridged piperazine ring.
    Holl R, Jung B, Schepmann D, Humpf HU, Grünert R, Bednarski PJ, Englberger W, Wünsch B.
    ChemMedChem; 2009 Dec 16; 4(12):2111-22. PubMed ID: 19827086
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  • 13. Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80) and related novel nonpeptide delta opioid receptor ligands.
    Calderon SN, Rice KC, Rothman RB, Porreca F, Flippen-Anderson JL, Kayakiri H, Xu H, Becketts K, Smith LE, Bilsky EJ, Davis P, Horvath R.
    J Med Chem; 1997 Feb 28; 40(5):695-704. PubMed ID: 9057856
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  • 16. Relationships between the structure of 6-allyl-6,8-diazabicyclo[3.2.2]nonane derivatives and their sigma receptor affinity and cytotoxic activity.
    Holl R, Schepmann D, Grünert R, Bednarski PJ, Wünsch B.
    Bioorg Med Chem; 2009 Jan 15; 17(2):777-93. PubMed ID: 19081725
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  • 18. Synthesis and pharmacological evaluation of enantiomerically pure endo-configured KOR agonists with 2-azabicyclo[3.2.1]octane scaffold.
    Jonas H, Aiello D, Frehland B, Lehmkuhl K, Schepmann D, Köhler J, Diana P, Wünsch B.
    Org Biomol Chem; 2021 Oct 06; 19(38):8384-8396. PubMed ID: 34528988
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  • 19. Synthesis and opioid activity of [D-Pro10]dynorphin A-(1-11) analogues with N-terminal alkyl substitution.
    Choi H, Murray TF, DeLander GE, Schmidt WK, Aldrich JV.
    J Med Chem; 1997 Aug 15; 40(17):2733-9. PubMed ID: 9276018
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  • 20. Synthesis and opioid activity of conformationally constrained dynorphin A analogues. 2. Conformational constraint in the "address" sequence.
    Arttamangkul S, Ishmael JE, Murray TF, Grandy DK, DeLander GE, Kieffer BL, Aldrich JV.
    J Med Chem; 1997 Apr 11; 40(8):1211-8. PubMed ID: 9111295
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