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356 related items for PubMed ID: 2044181

  • 1. Effect of phenethyl isothiocyanate on the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured rat lung tissue.
    Doerr-O'Rourke K, Trushin N, Hecht SS, Stoner GD.
    Carcinogenesis; 1991 Jun; 12(6):1029-34. PubMed ID: 2044181
    [Abstract] [Full Text] [Related]

  • 2. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates.
    Smith TJ, Guo ZY, Thomas PE, Chung FL, Morse MA, Elkind K, Yang CS.
    Cancer Res; 1990 Nov 01; 50(21):6817-22. PubMed ID: 2208146
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  • 4. Effect of phenethyl isothiocyanate on the metabolism of tobacco-specific nitrosamines by cultured rat oral tissue.
    Murphy SE, Heiblum R, King PG, Bowman D, Davis WJ, Stoner GD.
    Carcinogenesis; 1991 Jun 01; 12(6):957-61. PubMed ID: 2044202
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  • 5. Effects of phenethyl isothiocyanate on the tissue distribution of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and metabolites in F344 rats.
    Staretz ME, Hecht SS.
    Cancer Res; 1995 Dec 01; 55(23):5580-8. PubMed ID: 7585638
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  • 8. Effects of long term dietary phenethyl isothiocyanate on the microsomal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats.
    Staretz ME, Koenig LA, Hecht SS.
    Carcinogenesis; 1997 Sep 01; 18(9):1715-22. PubMed ID: 9328166
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  • 9. Mechanisms of inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation in mouse by dietary phenethyl isothiocyanate.
    Smith TJ, Guo Z, Li C, Ning SM, Thomas PE, Yang CS.
    Cancer Res; 1993 Jul 15; 53(14):3276-82. PubMed ID: 8324738
    [Abstract] [Full Text] [Related]

  • 10. The profile of urinary metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rats is determined by its pulmonary metabolism.
    Schneider T, Frei E, Wiessler M.
    Chem Biol Interact; 1999 Apr 15; 118(3):247-66. PubMed ID: 10362230
    [Abstract] [Full Text] [Related]

  • 11. Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in lung tissue from mouse, rat, hamster, and man.
    Richter E, Engl J, Friesenegger S, Tricker AR.
    Chem Res Toxicol; 2009 Jun 15; 22(6):1008-17. PubMed ID: 19408892
    [Abstract] [Full Text] [Related]

  • 12. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice.
    Guo Z, Smith TJ, Wang E, Eklind KI, Chung FL, Yang CS.
    Carcinogenesis; 1993 Jun 15; 14(6):1167-73. PubMed ID: 8508504
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  • 13. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human kidney epithelial cells transfected with rat CYP2B1 cDNA.
    Lacroix D, Desrochers M, Castonguay A, Anderson A.
    Carcinogenesis; 1993 Aug 15; 14(8):1639-42. PubMed ID: 8353848
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  • 14. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate.
    Smith TJ, Guo Z, Guengerich FP, Yang CS.
    Carcinogenesis; 1996 Apr 15; 17(4):809-13. PubMed ID: 8625495
    [Abstract] [Full Text] [Related]

  • 15. Evidence for an important role of DNA pyridyloxobutylation in rat lung carcinogenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: effects of dose and phenethyl isothiocyanate.
    Staretz ME, Foiles PG, Miglietta LM, Hecht SS.
    Cancer Res; 1997 Jan 15; 57(2):259-66. PubMed ID: 9000565
    [Abstract] [Full Text] [Related]

  • 16. Effects of isothiocyanates on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and benzo[a]pyrene by hamster and rat liver microsomes.
    Hamilton SM, Teel RW.
    Anticancer Res; 1994 Jan 15; 14(3A):1089-94. PubMed ID: 8074455
    [Abstract] [Full Text] [Related]

  • 17. Cell specificity for the pulmonary metabolism of tobacco-specific nitrosamines in the Fischer rat.
    Belinsky SA, White CM, Trushin N, Hecht SS.
    Carcinogenesis; 1989 Dec 15; 10(12):2269-74. PubMed ID: 2591016
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  • 18. Metabolism and DNA single strand breaks induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its analogues in primary culture of rat hepatocytes.
    Liu LL, Alaoui-Jamali MA, el Alami N, Castonguay A.
    Cancer Res; 1990 Mar 15; 50(6):1810-6. PubMed ID: 2306734
    [Abstract] [Full Text] [Related]

  • 19. Effects of aromatic isothiocyanates on tumorigenicity, O6-methylguanine formation, and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung.
    Morse MA, Amin SG, Hecht SS, Chung FL.
    Cancer Res; 1989 Jun 01; 49(11):2894-7. PubMed ID: 2720649
    [Abstract] [Full Text] [Related]

  • 20. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in isolated rat lung and liver.
    Schrader E, Hirsch-Ernst KI, Richter E, Foth H.
    Naunyn Schmiedebergs Arch Pharmacol; 1998 Mar 01; 357(3):336-43. PubMed ID: 9550307
    [Abstract] [Full Text] [Related]


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