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Journal Abstract Search

315 related items for PubMed ID: 2044637

  • 1. Lowering of plasma cholesterol levels in animals by lovastatin and simvastatin.
    Chao Y, Chen JS, Hunt VM, Kuron GW, Karkas JD, Liou R, Alberts AW.
    Eur J Clin Pharmacol; 1991; 40 Suppl 1():S11-4. PubMed ID: 2044637
    [Abstract] [Full Text] [Related]

  • 2. Tissue-selective acute effects of inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase on cholesterol biosynthesis in lens.
    Mosley ST, Kalinowski SS, Schafer BL, Tanaka RD.
    J Lipid Res; 1989 Sep; 30(9):1411-20. PubMed ID: 2513368
    [Abstract] [Full Text] [Related]

  • 3. Lovastatin and simvastatin--inhibitors of HMG CoA reductase and cholesterol biosynthesis.
    Alberts AW.
    Cardiology; 1990 Sep; 77 Suppl 4():14-21. PubMed ID: 2073667
    [Abstract] [Full Text] [Related]

  • 4. Regulation of HMG-CoA reductase, apoprotein-B and LDL receptor gene expression by the hypocholesterolemic drugs simvastatin and ciprofibrate in Hep G2, human and rat hepatocytes.
    Qin W, Infante J, Wang SR, Infante R.
    Biochim Biophys Acta; 1992 Jul 09; 1127(1):57-66. PubMed ID: 1627634
    [Abstract] [Full Text] [Related]

  • 5. In vitro myotoxicity of the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, pravastatin, lovastatin, and simvastatin, using neonatal rat skeletal myocytes.
    Masters BA, Palmoski MJ, Flint OP, Gregg RE, Wang-Iverson D, Durham SK.
    Toxicol Appl Pharmacol; 1995 Mar 09; 131(1):163-74. PubMed ID: 7878672
    [Abstract] [Full Text] [Related]

  • 6. Pravastatin inhibited the cholesterol synthesis in human hepatoma cell line Hep G2 less than simvastatin and lovastatin, which is reflected in the upregulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and squalene synthase.
    Cohen LH, van Vliet A, Roodenburg L, Jansen LM, Griffioen M.
    Biochem Pharmacol; 1993 Jun 09; 45(11):2203-8. PubMed ID: 8517861
    [Abstract] [Full Text] [Related]

  • 7. Effect of simvastatin (MK-733) on the regulation of cholesterol synthesis in Hep G2 cells.
    Nagata Y, Hidaka Y, Ishida F, Kamei T.
    Biochem Pharmacol; 1990 Aug 15; 40(4):843-50. PubMed ID: 2167097
    [Abstract] [Full Text] [Related]

  • 8. The synergistic hypocholesterolemic activity of the potent cholesterol absorption inhibitor, ezetimibe, in combination with 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors in dogs.
    Davis HR, Pula KK, Alton KB, Burrier RE, Watkins RW.
    Metabolism; 2001 Oct 15; 50(10):1234-41. PubMed ID: 11586500
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of cholesterol synthesis and hepatic 3-hydroxy-3-methylglutaryl--CoA reductase in rats by simvastatin and pravastatin.
    Del Puppo M, Rauli S, Galli Kienle M.
    Lipids; 1995 Nov 15; 30(11):1057-61. PubMed ID: 8569435
    [Abstract] [Full Text] [Related]

  • 10. Tissue-selective inhibition of cholesterol synthesis in vivo by pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.
    Koga T, Shimada Y, Kuroda M, Tsujita Y, Hasegawa K, Yamazaki M.
    Biochim Biophys Acta; 1990 Jul 16; 1045(2):115-20. PubMed ID: 2116173
    [Abstract] [Full Text] [Related]

  • 11. Effects of simvastatin, a cholesterol synthesis inhibitor, on phosphatidylcholine synthesis in HepG2 cells.
    Yanagita T, Yamamoto K, Ishida S, Sonda K, Morito F, Saku K, Sakai T.
    Clin Ther; 1994 Jul 16; 16(2):200-8. PubMed ID: 8062316
    [Abstract] [Full Text] [Related]

  • 12. Pharmacological profile of a novel synthetic inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    Aoki T, Nishimura H, Nakagawa S, Kojima J, Suzuki H, Tamaki T, Wada Y, Yokoo N, Sato F, Kimata H, Kitahara M, Toyoda K, Sakashita M, Saito Y.
    Arzneimittelforschung; 1997 Aug 16; 47(8):904-9. PubMed ID: 9296275
    [Abstract] [Full Text] [Related]

  • 13. Pharmacology of competitive inhibitors of HMG-CoA reductase.
    Corsini A, Maggi FM, Catapano AL.
    Pharmacol Res; 1995 Jan 16; 31(1):9-27. PubMed ID: 7784310
    [No Abstract] [Full Text] [Related]

  • 14. RG 12561 (dalvastatin): a novel synthetic inhibitor of HMG-CoA reductase and cholesterol-lowering agent.
    Amin D, Gustafson SK, Weinacht JM, Cornell SA, Neuenschwander K, Kosmider B, Scotese AC, Regan JR, Perrone MH.
    Pharmacology; 1993 Jan 16; 46(1):13-22. PubMed ID: 8434028
    [Abstract] [Full Text] [Related]

  • 15. [Extended worldwide experience. HMG-CoA reductase inhibitors: lovastatin and simvastatin].
    Mantell G.
    Therapie; 1992 Jan 16; 47(2):161-4. PubMed ID: 1412144
    [Abstract] [Full Text] [Related]

  • 16.
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    [No Abstract] [Full Text] [Related]

  • 17. Cholesterol synthesis inhibitors do not reduce Lp(a) levels in normocholesterolemic patients.
    Pazzucconi F, Franceschini G, Gianfranceschi G, Campagnoli G, Sirtori CR.
    Pharmacol Res; 1996 Jan 16; 34(3-4):131-3. PubMed ID: 9051704
    [Abstract] [Full Text] [Related]

  • 18. Subcutaneous administration of HMG-CoA reductase inhibitors in hyperlipidaemic and normal rats.
    Joles J, Willekes-Koolschijn N, Koomans H, Van Tol A, Geelhoed-Mieras T, Crommelin D, Van Bloois L, Krajnc-Franken M, Cohen L, Griffioen M.
    Lab Anim; 1992 Oct 16; 26(4):269-80. PubMed ID: 1447905
    [Abstract] [Full Text] [Related]

  • 19. Relative lipophilicities, solubilities, and structure-pharmacological considerations of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors pravastatin, lovastatin, mevastatin, and simvastatin.
    Serajuddin AT, Ranadive SA, Mahoney EM.
    J Pharm Sci; 1991 Sep 16; 80(9):830-4. PubMed ID: 1800703
    [Abstract] [Full Text] [Related]

  • 20. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and hepatic apolipoprotein B secretion.
    Huff MW, Burnett JR.
    Curr Opin Lipidol; 1997 Jun 16; 8(3):138-45. PubMed ID: 9211061
    [Abstract] [Full Text] [Related]

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