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762 related items for PubMed ID: 20456425

  • 1. Concomitant inactivation of the epidermal growth factor receptor, phosphatidylinositol 3-kinase/Akt and Janus tyrosine kinase 2/signal transducer and activator of transcription 3 signalling pathways in cardiotoxin III-treated A549 cells.
    Su JC, Lin KL, Chien CM, Chuang PW, Chang LS, Lin SR.
    Clin Exp Pharmacol Physiol; 2010 Aug; 37(8):833-40. PubMed ID: 20456425
    [Abstract] [Full Text] [Related]

  • 2. Down-regulation of the JAK2/PI3K-mediated signaling activation is involved in Taiwan cobra cardiotoxin III-induced apoptosis of human breast MDA-MB-231 cancer cells.
    Lin KL, Su JC, Chien CM, Chuang PW, Chang LS, Lin SR.
    Toxicon; 2010 Jun 15; 55(7):1263-73. PubMed ID: 20144642
    [Abstract] [Full Text] [Related]

  • 3. Taiwan cobra cardiotoxin III inhibits Src kinase leading to apoptosis and cell cycle arrest of oral squamous cell carcinoma Ca9-22 cells.
    Chien CM, Chang SY, Lin KL, Chiu CC, Chang LS, Lin SR.
    Toxicon; 2010 Sep 15; 56(4):508-20. PubMed ID: 20493203
    [Abstract] [Full Text] [Related]

  • 4. Naphtho[1,2-b]furan-4,5-dione inactivates EGFR and PI3K/Akt signaling pathways in human lung adenocarcinoma A549 cells.
    Su JC, Lin KL, Chien CM, Tseng CH, Chen YL, Chang LS, Lin SR.
    Life Sci; 2010 Jan 30; 86(5-6):207-13. PubMed ID: 20036260
    [Abstract] [Full Text] [Related]

  • 5. Naphtho[1,2-b]furan-4,5-dione disrupts Janus kinase-2 and induces apoptosis in breast cancer MDA-MB-231 cells.
    Lin KL, Su JC, Chien CM, Tseng CH, Chen YL, Chang LS, Lin SR.
    Toxicol In Vitro; 2010 Jun 30; 24(4):1158-67. PubMed ID: 20197088
    [Abstract] [Full Text] [Related]

  • 6. Up-regulation of Bax and endonuclease G, and down-modulation of Bcl-XL involved in cardiotoxin III-induced apoptosis in K562 cells.
    Yang SH, Chien CM, Lu MC, Lin YH, Hu XW, Lin SR.
    Exp Mol Med; 2006 Aug 31; 38(4):435-44. PubMed ID: 16953123
    [Abstract] [Full Text] [Related]

  • 7. Inactivation of epidermal growth factor receptor and downstream pathways in oral squamous cell carcinoma Ca9-22 cells by cardiotoxin III from Naja naja atra.
    Chien CM, Lin KL, Su JC, Chang LS, Lin SR.
    J Nat Prod; 2009 Oct 31; 72(10):1735-40. PubMed ID: 19754129
    [Abstract] [Full Text] [Related]

  • 8. Naphtho[1,2-b]furan-4,5-dione induces apoptosis of oral squamous cell carcinoma: involvement of EGF receptor/PI3K/Akt signaling pathway.
    Chien CM, Lin KL, Su JC, Chuang PW, Tseng CH, Chen YL, Chang LS, Lin SR.
    Eur J Pharmacol; 2010 Jun 25; 636(1-3):52-8. PubMed ID: 20371243
    [Abstract] [Full Text] [Related]

  • 9. Mechanisms of cardiotoxin lll-induced apoptosis in human colorectal cancer colo205 cells.
    Tsai CH, Yang SH, Chien CM, Lu MC, Lo CS, Lin YH, Hu XW, Lin SR.
    Clin Exp Pharmacol Physiol; 2006 Mar 25; 33(3):177-82. PubMed ID: 16487259
    [Abstract] [Full Text] [Related]

  • 10. Furano-1,2-naphthoquinone inhibits EGFR signaling associated with G2/M cell cycle arrest and apoptosis in A549 cells.
    Su JC, Lin KL, Chien CM, Tseng CH, Chen YL, Chang LS, Lin SR.
    Cell Biochem Funct; 2010 Dec 02; 28(8):695-705. PubMed ID: 21104938
    [Abstract] [Full Text] [Related]

  • 11. Cardiotoxin III suppresses MDA-MB-231 cell metastasis through the inhibition of EGF/EGFR-mediated signaling pathway.
    Tsai PC, Hsieh CY, Chiu CC, Wang CK, Chang LS, Lin SR.
    Toxicon; 2012 Oct 02; 60(5):734-43. PubMed ID: 22683533
    [Abstract] [Full Text] [Related]

  • 12. Cardiotoxin III induces apoptosis in K562 cells through a mitochondrial-mediated pathway.
    Yang SH, Chien CM, Lu MC, Lu YJ, Wu ZZ, Lin SR.
    Clin Exp Pharmacol Physiol; 2005 Jul 02; 32(7):515-20. PubMed ID: 16026508
    [Abstract] [Full Text] [Related]

  • 13. EGFR-induced cell migration is mediated predominantly by the JAK-STAT pathway in primary esophageal keratinocytes.
    Andl CD, Mizushima T, Oyama K, Bowser M, Nakagawa H, Rustgi AK.
    Am J Physiol Gastrointest Liver Physiol; 2004 Dec 02; 287(6):G1227-37. PubMed ID: 15284024
    [Abstract] [Full Text] [Related]

  • 14. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ, Ng LT, Lin CC.
    Eur J Pharmacol; 2005 Aug 22; 518(2-3):96-106. PubMed ID: 16054126
    [Abstract] [Full Text] [Related]

  • 15. Cardiotoxin III induces c-jun N-terminal kinase-dependent apoptosis in HL-60 human leukaemia cells.
    Chien CM, Yang SH, Yang CC, Chang LS, Lin SR.
    Cell Biochem Funct; 2008 Aug 22; 26(1):111-8. PubMed ID: 17514639
    [Abstract] [Full Text] [Related]

  • 16. Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells.
    Lee DH, Szczepanski MJ, Lee YJ.
    J Cell Biochem; 2009 Apr 15; 106(6):1113-22. PubMed ID: 19229860
    [Abstract] [Full Text] [Related]

  • 17. Effects of cardiotoxin III on NF-kappaB function, proliferation, and apoptosis in human breast MCF-7 cancer cells.
    Chiu CC, Lin KL, Chien CM, Chang LS, Lin SR.
    Oncol Res; 2009 Apr 15; 17(7):311-21. PubMed ID: 19408576
    [Abstract] [Full Text] [Related]

  • 18. Induction of apoptosis in human leukemia K562 cells by cardiotoxin III.
    Yang SH, Lu MC, Chien CM, Tsai CH, Lu YJ, Hour TC, Lin SR.
    Life Sci; 2005 Apr 08; 76(21):2513-22. PubMed ID: 15763081
    [Abstract] [Full Text] [Related]

  • 19. Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.
    Tan SM, Li F, Rajendran P, Kumar AP, Hui KM, Sethi G.
    J Pharmacol Exp Ther; 2010 Jul 08; 334(1):285-93. PubMed ID: 20378717
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of PI3-kinase-Akt pathway enhances dexamethasone-induced apoptosis in a human follicular lymphoma cell line.
    Nuutinen U, Postila V, Mättö M, Eeva J, Ropponen A, Eray M, Riikonen P, Pelkonen J.
    Exp Cell Res; 2006 Feb 01; 312(3):322-30. PubMed ID: 16309671
    [Abstract] [Full Text] [Related]

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