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Journal Abstract Search


525 related items for PubMed ID: 20459702

  • 1. Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway.
    Ryu K, Susa M, Choy E, Yang C, Hornicek FJ, Mankin HJ, Duan Z.
    BMC Cancer; 2010 May 10; 10():187. PubMed ID: 20459702
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  • 3. Activation of signal transducer and activator of transcription 3 (Stat3) pathway in osteosarcoma cells and overexpression of phosphorylated-Stat3 correlates with poor prognosis.
    Ryu K, Choy E, Yang C, Susa M, Hornicek FJ, Mankin H, Duan Z.
    J Orthop Res; 2010 Jul 10; 28(7):971-8. PubMed ID: 20063378
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  • 6. Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia.
    Konopleva M, Tsao T, Ruvolo P, Stiouf I, Estrov Z, Leysath CE, Zhao S, Harris D, Chang S, Jackson CE, Munsell M, Suh N, Gribble G, Honda T, May WS, Sporn MB, Andreeff M.
    Blood; 2002 Jan 01; 99(1):326-35. PubMed ID: 11756188
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  • 7. The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells.
    Stadheim TA, Suh N, Ganju N, Sporn MB, Eastman A.
    J Biol Chem; 2002 May 10; 277(19):16448-55. PubMed ID: 11880365
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  • 9. Cinnamaldehyde derivative (CB-PIC) sensitizes chemo-resistant cancer cells to drug-induced apoptosis via suppression of MDR1 and its upstream STAT3 and AKT signalling.
    Yun M, Lee D, Park MN, Kim EO, Sohn EJ, Kwon BM, Kim SH.
    Cell Physiol Biochem; 2015 May 10; 35(5):1821-30. PubMed ID: 25833196
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  • 10. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells.
    Shishodia S, Sethi G, Konopleva M, Andreeff M, Aggarwal BB.
    Clin Cancer Res; 2006 Mar 15; 12(6):1828-38. PubMed ID: 16551868
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  • 11. Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells.
    Kim KB, Lotan R, Yue P, Sporn MB, Suh N, Gribble GW, Honda T, Wu GS, Hong WK, Sun SY.
    Mol Cancer Ther; 2002 Jan 15; 1(3):177-84. PubMed ID: 12467212
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  • 12. Bardoxolone Methyl Suppresses Hepatitis B Virus Large Surface Protein Variant W4P-Related Carcinogenesis and Hepatocellular Carcinoma Cell Proliferation Via the Inhibition of Signal Transducer and Activator of Transcription 3 Signaling.
    Gee MS, Kang SB, Kim N, Choi J, Kim NJ, Kim BJ, Inn KS, Lee JK.
    Pharmacology; 2018 Jan 15; 102(1-2):105-113. PubMed ID: 29953997
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  • 13. Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer.
    Hyer ML, Shi R, Krajewska M, Meyer C, Lebedeva IV, Fisher PB, Reed JC.
    Cancer Res; 2008 Apr 15; 68(8):2927-33. PubMed ID: 18413762
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  • 15. ROS mediate proapoptotic and antisurvival activity of oleanane triterpenoid CDDO-Me in ovarian cancer cells.
    Gao X, Liu Y, Deeb D, Liu P, Liu A, Arbab AS, Gautam SC.
    Anticancer Res; 2013 Jan 15; 33(1):215-21. PubMed ID: 23267148
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  • 16. Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-kappaB and Notch1 signaling.
    Gao X, Deeb D, Jiang H, Liu Y, Dulchavsky SA, Gautam SC.
    J Neurooncol; 2007 Sep 15; 84(2):147-57. PubMed ID: 17361329
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  • 17. CDDO-me induces apoptosis and inhibits Akt, mTOR and NF-kappaB signaling proteins in prostate cancer cells.
    Deeb D, Gao X, Dulchavsky SA, Gautam SC.
    Anticancer Res; 2007 Sep 15; 27(5A):3035-44. PubMed ID: 17970042
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  • 18. STAT3 inhibitor, cucurbitacin I, is a novel therapeutic agent for osteosarcoma.
    Oi T, Asanuma K, Matsumine A, Matsubara T, Nakamura T, Iino T, Asanuma Y, Goto M, Okuno K, Kakimoto T, Yada Y, Sudo A.
    Int J Oncol; 2016 Dec 15; 49(6):2275-2284. PubMed ID: 27840900
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  • 19. Characterization of STAT3 activation and expression in canine and human osteosarcoma.
    Fossey SL, Liao AT, McCleese JK, Bear MD, Lin J, Li PK, Kisseberth WC, London CA.
    BMC Cancer; 2009 Mar 10; 9():81. PubMed ID: 19284568
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  • 20. Methyl 3-hydroxyimino-11-oxoolean-12-en-28-oate (HIMOXOL), a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MDA-MB-231 breast cancer cells.
    Lisiak N, Paszel-Jaworska A, Bednarczyk-Cwynar B, Zaprutko L, Kaczmarek M, Rybczyńska M.
    Chem Biol Interact; 2014 Feb 05; 208():47-57. PubMed ID: 24291674
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