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486 related items for PubMed ID: 20463006
1. MJ-29 inhibits tubulin polymerization, induces mitotic arrest, and triggers apoptosis via cyclin-dependent kinase 1-mediated Bcl-2 phosphorylation in human leukemia U937 cells. Yang JS, Hour MJ, Huang WW, Lin KL, Kuo SC, Chung JG. J Pharmacol Exp Ther; 2010 Aug; 334(2):477-88. PubMed ID: 20463006 [Abstract] [Full Text] [Related]
2. The novel synthesized 2-(3-(methylamino)phenyl)-6-(pyrrolidin-1-yl)quinolin-4-one (Smh-3) compound induces G2/M phase arrest and mitochondrial-dependent apoptotic cell death through inhibition of CDK1 and AKT activity in HL-60 human leukemia cells. Huang SM, Yang JS, Tsai SC, Chen MH, Hsu MH, Lin HY, Chou LC, Chinag JH, Lee KH, Huang LJ, Kuo SC. Int J Oncol; 2011 May; 38(5):1357-64. PubMed ID: 21344160 [Abstract] [Full Text] [Related]
3. BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo. Kuo CC, Hsieh HP, Pan WY, Chen CP, Liou JP, Lee SJ, Chang YL, Chen LT, Chen CT, Chang JY. Cancer Res; 2004 Jul 01; 64(13):4621-8. PubMed ID: 15231674 [Abstract] [Full Text] [Related]
4. Double blockade of cell cycle at g(1)-s transition and m phase by 3-iodoacetamido benzoyl ethyl ester, a new type of tubulin ligand. Jiang JD, Denner L, Ling YH, Li JN, Davis A, Wang Y, Li Y, Roboz J, Wang LG, Perez-Soler R, Marcelli M, Bekesi G, Holland JF. Cancer Res; 2002 Nov 01; 62(21):6080-8. PubMed ID: 12414632 [Abstract] [Full Text] [Related]
5. Selective induction of G2/M arrest and apoptosis in HL-60 by a potent anticancer agent, HMJ-38. Yang JS, Hour MJ, Kuo SC, Huang LJ, Lee MR. Anticancer Res; 2004 Nov 01; 24(3a):1769-78. PubMed ID: 15274354 [Abstract] [Full Text] [Related]
6. Induction of mitotic arrest and apoptosis by a novel synthetic quinolone analogue, CWC-8, via intrinsic and extrinsic apoptotic pathways in human osteogenic sarcoma U-2 OS cells. Chang YH, Yang JS, Kuo SC, Chung JG. Anticancer Res; 2009 Aug 01; 29(8):3139-48. PubMed ID: 19661327 [Abstract] [Full Text] [Related]
7. Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways. Chen YC, Lu PH, Pan SL, Teng CM, Kuo SC, Lin TP, Ho YF, Huang YC, Guh JH. Biochem Pharmacol; 2007 Jun 30; 74(1):10-9. PubMed ID: 17475221 [Abstract] [Full Text] [Related]
8. beta-Sitosterol induces G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways. Moon DO, Kim MO, Choi YH, Kim GY. Cancer Lett; 2008 Jun 18; 264(2):181-91. PubMed ID: 18314257 [Abstract] [Full Text] [Related]
9. Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo. Hsu YL, Cho CY, Kuo PL, Huang YT, Lin CC. J Pharmacol Exp Ther; 2006 Aug 18; 318(2):484-94. PubMed ID: 16632641 [Abstract] [Full Text] [Related]
10. Betuletol 3-methyl ether induces G(2)-M phase arrest and activates the sphingomyelin and MAPK pathways in human leukemia cells. Rubio S, Quintana J, Eiroa JL, Triana J, Estévez F. Mol Carcinog; 2010 Jan 18; 49(1):32-43. PubMed ID: 19676104 [Abstract] [Full Text] [Related]
11. DMNQ-S17 inhibits constitutive NF-kappaB activation leading to induction of apoptosis through the activation of caspase-3 in human myeloid leukemia U937 cells. Park MJ, Kwon HY, Lee EO, Lee HJ, Ahn KS, Kim MO, Kim CH, Ahn KS, Kim SH. Life Sci; 2008 Sep 26; 83(13-14):460-7. PubMed ID: 18718843 [Abstract] [Full Text] [Related]
12. Melittin induces Bcl-2 and caspase-3-dependent apoptosis through downregulation of Akt phosphorylation in human leukemic U937 cells. Moon DO, Park SY, Choi YH, Kim ND, Lee C, Kim GY. Toxicon; 2008 Jan 26; 51(1):112-20. PubMed ID: 17936321 [Abstract] [Full Text] [Related]
13. A novel polysaccharide, isolated from Angelica sinensis (Oliv.) Diels induces the apoptosis of cervical cancer HeLa cells through an intrinsic apoptotic pathway. Cao W, Li XQ, Wang X, Fan HT, Zhang XN, Hou Y, Liu SB, Mei QB. Phytomedicine; 2010 Jul 26; 17(8-9):598-605. PubMed ID: 20092988 [Abstract] [Full Text] [Related]
14. 5,7,3'-Trihydroxy-3,4'-dimethoxyflavone inhibits the tubulin polymerization and activates the sphingomyelin pathway. Torres F, Quintana J, Estévez F. Mol Carcinog; 2011 Feb 26; 50(2):113-22. PubMed ID: 21229608 [Abstract] [Full Text] [Related]
15. 6,7-Dimethoxy-3-(3-methoxyphenyl)isoquinolin-1-amine induces mitotic arrest and apoptotic cell death through the activation of spindle assembly checkpoint in human cervical cancer cells. Chung KS, Choi HE, Shin JS, Cho YW, Choi JH, Cho WJ, Lee KT. Carcinogenesis; 2013 Aug 26; 34(8):1852-60. PubMed ID: 23615402 [Abstract] [Full Text] [Related]
16. The induction of G2/M cell-cycle arrest and apoptosis by cucurbitacin E is associated with increased phosphorylation of eIF2alpha in leukemia cells. Li Y, Wang R, Ma E, Deng Y, Wang X, Xiao J, Jing Y. Anticancer Drugs; 2010 Apr 26; 21(4):389-400. PubMed ID: 20110807 [Abstract] [Full Text] [Related]
17. Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and -resistant human tumor cells. Chang JY, Chang CY, Kuo CC, Chen LT, Wein YS, Kuo YH. Mol Pharmacol; 2004 Jan 26; 65(1):77-84. PubMed ID: 14722239 [Abstract] [Full Text] [Related]
18. MSFTZ, a flavanone derivative, induces human hepatoma cell apoptosis via a reactive oxygen species- and caspase-dependent mitochondrial pathway. Ying M, Tu C, Ying H, Hu Y, He Q, Yang B. J Pharmacol Exp Ther; 2008 Jun 26; 325(3):758-65. PubMed ID: 18323457 [Abstract] [Full Text] [Related]
19. Arsenic trioxide induces G2/M growth arrest and apoptosis after caspase-3 activation and bcl-2 phosphorylation in promonocytic U937 cells. Park JW, Choi YJ, Jang MA, Baek SH, Lim JH, Passaniti T, Kwon TK. Biochem Biophys Res Commun; 2001 Aug 31; 286(4):726-34. PubMed ID: 11520058 [Abstract] [Full Text] [Related]
20. Eriocalyxin B induces apoptosis in lymphoma cells through multiple cellular signaling pathways. Zhang YW, Jiang XX, Chen QS, Shi WY, Wang L, Sun HD, Shen ZX, Chen Z, Chen SJ, Zhao WL. Exp Hematol; 2010 Mar 31; 38(3):191-201. PubMed ID: 20045442 [Abstract] [Full Text] [Related] Page: [Next] [New Search]