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Journal Abstract Search

161 related items for PubMed ID: 20466651

  • 1. A new class of mechanism-based inhibitors for Trypanosoma cruzi trans-sialidase and their influence on parasite virulence.
    Carvalho ST, Sola-Penna M, Oliveira IA, Pita S, Gonçalves AS, Neves BC, Sousa FR, Freire-de-Lima L, Kurogochi M, Hinou H, Nishimura S, Mendonça-Previato L, Previato JO, Todeschini AR.
    Glycobiology; 2010 Aug; 20(8):1034-45. PubMed ID: 20466651
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  • 2. Rational drug design in parasitology: trans-sialidase as a case study for Chagas disease.
    Neres J, Bryce RA, Douglas KT.
    Drug Discov Today; 2008 Feb; 13(3-4):110-7. PubMed ID: 18275908
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  • 3. Lactose derivatives are inhibitors of Trypanosoma cruzi trans-sialidase activity toward conventional substrates in vitro and in vivo.
    Agustí R, París G, Ratier L, Frasch AC, de Lederkremer RM.
    Glycobiology; 2004 Jul; 14(7):659-70. PubMed ID: 15070857
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  • 4. Trypanosoma cruzi trans-sialidase as a drug target against Chagas disease (American trypanosomiasis).
    Miller BR, Roitberg AE.
    Future Med Chem; 2013 Oct; 5(15):1889-900. PubMed ID: 24144418
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  • 5. Donor substrate binding to trans-sialidase of Trypanosoma cruzi as studied by STD NMR.
    Blume A, Neubacher B, Thiem J, Peters T.
    Carbohydr Res; 2007 Sep 03; 342(12-13):1904-9. PubMed ID: 17597593
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  • 6. Sialic acid C-glycosides with aromatic residues: investigating enzyme binding and inhibition of Trypanosoma cruzi trans-sialidase.
    Meinke S, Schroven A, Thiem J.
    Org Biomol Chem; 2011 Jun 21; 9(12):4487-97. PubMed ID: 21528140
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  • 10. Potent inhibitor scaffold against Trypanosoma cruzi trans-sialidase.
    Arioka S, Sakagami M, Uematsu R, Yamaguchi H, Togame H, Takemoto H, Hinou H, Nishimura S.
    Bioorg Med Chem; 2010 Feb 15; 18(4):1633-40. PubMed ID: 20097567
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  • 14. Discovery of novel inhibitors of Trypanosoma cruzi trans-sialidase from in silico screening.
    Neres J, Brewer ML, Ratier L, Botti H, Buschiazzo A, Edwards PN, Mortenson PN, Charlton MH, Alzari PM, Frasch AC, Bryce RA, Douglas KT.
    Bioorg Med Chem Lett; 2009 Feb 01; 19(3):589-96. PubMed ID: 19144516
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  • 19. Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile.
    Watts AG, Damager I, Amaya ML, Buschiazzo A, Alzari P, Frasch AC, Withers SG.
    J Am Chem Soc; 2003 Jun 25; 125(25):7532-3. PubMed ID: 12812490
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