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Journal Abstract Search

158 related items for PubMed ID: 20466821

  • 1. Prediction of functionally selective allosteric interactions at an M3 muscarinic acetylcholine receptor mutant using Saccharomyces cerevisiae.
    Stewart GD, Sexton PM, Christopoulos A.
    Mol Pharmacol; 2010 Aug; 78(2):205-14. PubMed ID: 20466821
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  • 4. Probe dependence in the allosteric modulation of a G protein-coupled receptor: implications for detection and validation of allosteric ligand effects.
    Valant C, Felder CC, Sexton PM, Christopoulos A.
    Mol Pharmacol; 2012 Jan; 81(1):41-52. PubMed ID: 21989256
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  • 5. Detection, quantitation, and verification of allosteric interactions of agents with labeled and unlabeled ligands at G protein-coupled receptors: interactions of strychnine and acetylcholine at muscarinic receptors.
    Lazareno S, Birdsall NJ.
    Mol Pharmacol; 1995 Aug; 48(2):362-78. PubMed ID: 7651370
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  • 7. Investigation of the interaction of a putative allosteric modulator, N-(2,3-diphenyl-1,2,4-thiadiazole-5-(2H)-ylidene) methanamine hydrobromide (SCH-202676), with M1 muscarinic acetylcholine receptors.
    Lanzafame A, Christopoulos A.
    J Pharmacol Exp Ther; 2004 Mar; 308(3):830-7. PubMed ID: 14617684
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  • 8. The M3-muscarinic acetylcholine receptor stimulates glucose uptake in L6 skeletal muscle cells by a CaMKK-AMPK-dependent mechanism.
    Merlin J, Evans BA, Csikasz RI, Bengtsson T, Summers RJ, Hutchinson DS.
    Cell Signal; 2010 Jul; 22(7):1104-13. PubMed ID: 20206685
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  • 9. Regulation of M2 muscarinic acetylcholine receptor expression and signaling by prolonged exposure to allosteric modulators.
    May LT, Lin Y, Sexton PM, Christopoulos A.
    J Pharmacol Exp Ther; 2005 Jan; 312(1):382-90. PubMed ID: 15333678
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  • 10. Determination of adenosine A1 receptor agonist and antagonist pharmacology using Saccharomyces cerevisiae: implications for ligand screening and functional selectivity.
    Stewart GD, Valant C, Dowell SJ, Mijaljica D, Devenish RJ, Scammells PJ, Sexton PM, Christopoulos A.
    J Pharmacol Exp Ther; 2009 Oct; 331(1):277-86. PubMed ID: 19641164
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  • 11. Activation of transfected M1 or M3 muscarinic acetylcholine receptors induces cell-cell adhesion of Chinese hamster ovary cells expressing endogenous cadherins.
    Shafer SH, Puhl HL, Phelps SH, Williams CL.
    Exp Cell Res; 1999 Apr 10; 248(1):148-59. PubMed ID: 10094822
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  • 12. The role of transmembrane domain 3 in the actions of orthosteric, allosteric, and atypical agonists of the M4 muscarinic acetylcholine receptor.
    Leach K, Davey AE, Felder CC, Sexton PM, Christopoulos A.
    Mol Pharmacol; 2011 May 10; 79(5):855-65. PubMed ID: 21300722
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  • 13. Generation of an agonistic binding site for blockers of the M(3) muscarinic acetylcholine receptor.
    Thor D, Schulz A, Hermsdorf T, Schöneberg T.
    Biochem J; 2008 May 15; 412(1):103-12. PubMed ID: 18237275
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  • 20. An investigation of whether agonist-selective receptor conformations occur with respect to M2 and M4 muscarinic acetylcholine receptor signalling via Gi/o and Gs proteins.
    Mistry R, Dowling MR, Challiss RA.
    Br J Pharmacol; 2005 Feb 15; 144(4):566-75. PubMed ID: 15655507
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