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130 related items for PubMed ID: 20473999

  • 1. Endoglin negatively regulates transforming growth factor beta1-induced profibrotic responses in intestinal fibroblasts.
    Burke JP, Watson RW, Mulsow JJ, Docherty NG, Coffey JC, O'Connell PR.
    Br J Surg; 2010 Jun; 97(6):892-901. PubMed ID: 20473999
    [Abstract] [Full Text] [Related]

  • 2. Bacterial lipopolysaccharide promotes profibrotic activation of intestinal fibroblasts.
    Burke JP, Cunningham MF, Watson RW, Docherty NG, Coffey JC, O'Connell PR.
    Br J Surg; 2010 Jul; 97(7):1126-34. PubMed ID: 20632282
    [Abstract] [Full Text] [Related]

  • 3. Simvastatin impairs smad-3 phosphorylation and modulates transforming growth factor beta1-mediated activation of intestinal fibroblasts.
    Burke JP, Watson RW, Murphy M, Docherty NG, Coffey JC, O'Connell PR.
    Br J Surg; 2009 May; 96(5):541-51. PubMed ID: 19358180
    [Abstract] [Full Text] [Related]

  • 4. Mechanism of the inhibitory effect of atorvastatin on endoglin expression induced by transforming growth factor-beta1 in cultured cardiac fibroblasts.
    Shyu KG, Wang BW, Chen WJ, Kuan P, Hung CR.
    Eur J Heart Fail; 2010 Mar; 12(3):219-26. PubMed ID: 20156938
    [Abstract] [Full Text] [Related]

  • 5. N-cadherin is overexpressed in Crohn's stricture fibroblasts and promotes intestinal fibroblast migration.
    Burke JP, Cunningham MF, Sweeney C, Docherty NG, O'Connell PR.
    Inflamm Bowel Dis; 2011 Aug; 17(8):1665-73. PubMed ID: 21287659
    [Abstract] [Full Text] [Related]

  • 6. Transforming growth factor-beta promotes pro-fibrotic behavior by serosal fibroblasts via PKC and ERK1/2 mitogen activated protein kinase cell signaling.
    Mulsow JJ, Watson RW, Fitzpatrick JM, O'Connell PR.
    Ann Surg; 2005 Dec; 242(6):880-7, discussion 887-9. PubMed ID: 16327498
    [Abstract] [Full Text] [Related]

  • 7. Smad7 blocks transforming growth factor-β1-induced gingival fibroblast-myofibroblast transition via inhibitory regulation of Smad2 and connective tissue growth factor.
    Sobral LM, Montan PF, Zecchin KG, Martelli-Junior H, Vargas PA, Graner E, Coletta RD.
    J Periodontol; 2011 Apr; 82(4):642-51. PubMed ID: 21054221
    [Abstract] [Full Text] [Related]

  • 8. Endoglin modulation of TGF-beta1-induced collagen synthesis is dependent on ERK1/2 MAPK activation.
    Rodríguez-Barbero A, Obreo J, Alvarez-Munoz P, Pandiella A, Bernabéu C, López-Novoa JM.
    Cell Physiol Biochem; 2006 Apr; 18(1-3):135-42. PubMed ID: 16914898
    [Abstract] [Full Text] [Related]

  • 9. S100A4 expression is increased in stricture fibroblasts from patients with fibrostenosing Crohn's disease and promotes intestinal fibroblast migration.
    Cunningham MF, Docherty NG, Burke JP, O'Connell PR.
    Am J Physiol Gastrointest Liver Physiol; 2010 Aug; 299(2):G457-66. PubMed ID: 20489045
    [Abstract] [Full Text] [Related]

  • 10. Simvastatin inhibits transforming growth factor-β1-induced expression of type I collagen, CTGF, and α-SMA in keloid fibroblasts.
    Mun JH, Kim YM, Kim BS, Kim JH, Kim MB, Ko HC.
    Wound Repair Regen; 2014 Aug; 22(1):125-33. PubMed ID: 24471776
    [Abstract] [Full Text] [Related]

  • 11. Endoglin expression regulates basal and TGF-beta1-induced extracellular matrix synthesis in cultured L6E9 myoblasts.
    Obreo J, Díez-Marques L, Lamas S, Düwell A, Eleno N, Bernabéu C, Pandiella A, López-Novoa JM, Rodríguez-Barbero A.
    Cell Physiol Biochem; 2004 Aug; 14(4-6):301-10. PubMed ID: 15319534
    [Abstract] [Full Text] [Related]

  • 12. Pirfenidone prevents radiation-induced intestinal fibrosis in rats by inhibiting fibroblast proliferation and differentiation and suppressing the TGF-β1/Smad/CTGF signaling pathway.
    Sun YW, Zhang YY, Ke XJ, Wu XJ, Chen ZF, Chi P.
    Eur J Pharmacol; 2018 Mar 05; 822():199-206. PubMed ID: 29374548
    [Abstract] [Full Text] [Related]

  • 13. Transforming growth factor (TGF)-β type I receptor kinase (ALK5) inhibitor alleviates profibrotic TGF-β1 responses in fibroblasts derived from Peyronie's plaque.
    Piao S, Choi MJ, Tumurbaatar M, Kim WJ, Jin HR, Shin SH, Tuvshintur B, Yin GN, Song JS, Kwon MH, Lee SJ, Han JY, Kim SJ, Ryu JK, Suh JK.
    J Sex Med; 2010 Oct 05; 7(10):3385-95. PubMed ID: 20233292
    [Abstract] [Full Text] [Related]

  • 14. Endogenous IGFBP-3 regulates excess collagen expression in intestinal smooth muscle cells of Crohn's disease strictures.
    Flynn RS, Mahavadi S, Murthy KS, Grider JR, Kellum JM, Akbari H, Kuemmerle JF.
    Inflamm Bowel Dis; 2011 Jan 05; 17(1):193-201. PubMed ID: 20848532
    [Abstract] [Full Text] [Related]

  • 15. Expression and regulation of connective tissue growth factor by transforming growth factor beta and tumour necrosis factor alpha in fibroblasts isolated from strictures in patients with Crohn's disease.
    Beddy D, Mulsow J, Watson RW, Fitzpatrick JM, O'Connell PR.
    Br J Surg; 2006 Oct 05; 93(10):1290-6. PubMed ID: 16838391
    [Abstract] [Full Text] [Related]

  • 16. Expression and functional analysis of endoglin in isolated liver cells and its involvement in fibrogenic Smad signalling.
    Meurer SK, Tihaa L, Borkham-Kamphorst E, Weiskirchen R.
    Cell Signal; 2011 Apr 05; 23(4):683-99. PubMed ID: 21146604
    [Abstract] [Full Text] [Related]

  • 17. Noncanonical STAT3 activation regulates excess TGF-β1 and collagen I expression in muscle of stricturing Crohn's disease.
    Li C, Iness A, Yoon J, Grider JR, Murthy KS, Kellum JM, Kuemmerle JF.
    J Immunol; 2015 Apr 01; 194(7):3422-31. PubMed ID: 25740948
    [Abstract] [Full Text] [Related]

  • 18. Fetal and adult fibroblasts have similar TGF-beta-mediated, Smad-dependent signaling pathways.
    Colwell AS, Krummel TM, Longaker MT, Lorenz HP.
    Plast Reconstr Surg; 2006 Jun 01; 117(7):2277-83. PubMed ID: 16772929
    [Abstract] [Full Text] [Related]

  • 19. Cub domain-containing protein 1 negatively regulates TGF-β signaling and myofibroblast differentiation.
    Noskovičová N, Heinzelmann K, Burgstaller G, Behr J, Eickelberg O.
    Am J Physiol Lung Cell Mol Physiol; 2018 May 01; 314(5):L695-L707. PubMed ID: 29351434
    [Abstract] [Full Text] [Related]

  • 20. Transcriptomic analysis of intestinal fibrosis-associated gene expression in response to medical therapy in Crohn's disease.
    Burke JP, Ferrante M, Dejaegher K, Watson RW, Docherty NG, De Hertogh G, Vermeire S, Rutgeerts P, D'Hoore A, Penninckx F, Geboes K, Van Assche G, O'Connell PR.
    Inflamm Bowel Dis; 2008 Sep 01; 14(9):1197-204. PubMed ID: 18452219
    [Abstract] [Full Text] [Related]

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