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261 related items for PubMed ID: 20484410

  • 1. cAMP-dependent activation of mammalian target of rapamycin (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4.
    Blancquaert S, Wang L, Paternot S, Coulonval K, Dumont JE, Harris TE, Roger PP.
    Mol Endocrinol; 2010 Jul; 24(7):1453-68. PubMed ID: 20484410
    [Abstract] [Full Text] [Related]

  • 2. Regulation of the phosphatidylinositol 3-kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and stimulating type TSH receptor antibodies in the thyroid gland.
    Suh JM, Song JH, Kim DW, Kim H, Chung HK, Hwang JH, Kim JM, Hwang ES, Chung J, Han JH, Cho BY, Ro HK, Shong M.
    J Biol Chem; 2003 Jun 13; 278(24):21960-71. PubMed ID: 12668683
    [Abstract] [Full Text] [Related]

  • 3. Transforming growth factor beta(1) selectively inhibits the cyclic AMP-dependent proliferation of primary thyroid epithelial cells by preventing the association of cyclin D3-cdk4 with nuclear p27(kip1).
    Depoortere F, Pirson I, Bartek J, Dumont JE, Roger PP.
    Mol Biol Cell; 2000 Mar 13; 11(3):1061-76. PubMed ID: 10712520
    [Abstract] [Full Text] [Related]

  • 4. A requirement for cyclin D3-cyclin-dependent kinase (cdk)-4 assembly in the cyclic adenosine monophosphate-dependent proliferation of thyrocytes.
    Depoortere F, Van Keymeulen A, Lukas J, Costagliola S, Bartkova J, Dumont JE, Bartek J, Roger PP, Dremier S.
    J Cell Biol; 1998 Mar 23; 140(6):1427-39. PubMed ID: 9508775
    [Abstract] [Full Text] [Related]

  • 5. The cyclin D3-CDK4-p27kip1 holoenzyme in thyroid epithelial cells: activation by TSH, inhibition by TGFbeta, and phosphorylations of its subunits demonstrated by two-dimensional gel electrophoresis.
    Coulonval K, Bockstaele L, Paternot S, Dumont JE, Roger PP.
    Exp Cell Res; 2003 Nov 15; 291(1):135-49. PubMed ID: 14597415
    [Abstract] [Full Text] [Related]

  • 6. Differential utilization of cyclin D1 and cyclin D3 in the distinct mitogenic stimulations by growth factors and TSH of human thyrocytes in primary culture.
    Paternot S, Dumont JE, Roger PP.
    Mol Endocrinol; 2006 Dec 15; 20(12):3279-92. PubMed ID: 16916940
    [Abstract] [Full Text] [Related]

  • 7. Cyclic AMP-dependent phosphorylation of cyclin D3-bound CDK4 determines the passage through the cell cycle restriction point in thyroid epithelial cells.
    Paternot S, Coulonval K, Dumont JE, Roger PP.
    J Biol Chem; 2003 Jul 18; 278(29):26533-40. PubMed ID: 12730225
    [Abstract] [Full Text] [Related]

  • 8. Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation.
    Rocha AS, Paternot S, Coulonval K, Dumont JE, Soares P, Roger PP.
    Mol Biol Cell; 2008 Nov 18; 19(11):4814-25. PubMed ID: 18799615
    [Abstract] [Full Text] [Related]

  • 9. MTOR downregulates iodide uptake in thyrocytes.
    de Souza EC, Padrón AS, Braga WM, de Andrade BM, Vaisman M, Nasciutti LE, Ferreira AC, de Carvalho DP.
    J Endocrinol; 2010 Jul 18; 206(1):113-20. PubMed ID: 20392814
    [Abstract] [Full Text] [Related]

  • 10. Luteinizing hormone stimulates mammalian target of rapamycin signaling in bovine luteal cells via pathways independent of AKT and mitogen-activated protein kinase: modulation of glycogen synthase kinase 3 and AMP-activated protein kinase.
    Hou X, Arvisais EW, Davis JS.
    Endocrinology; 2010 Jun 18; 151(6):2846-57. PubMed ID: 20351317
    [Abstract] [Full Text] [Related]

  • 11. Human chorionic gonadotropin stimulates theca-interstitial cell proliferation and cell cycle regulatory proteins by a cAMP-dependent activation of AKT/mTORC1 signaling pathway.
    Palaniappan M, Menon KM.
    Mol Endocrinol; 2010 Sep 18; 24(9):1782-93. PubMed ID: 20660299
    [Abstract] [Full Text] [Related]

  • 12. Hydrogen peroxide impairs insulin-stimulated assembly of mTORC1.
    Zhang L, Kimball SR, Jefferson LS, Shenberger JS.
    Free Radic Biol Med; 2009 Jun 01; 46(11):1500-9. PubMed ID: 19281842
    [Abstract] [Full Text] [Related]

  • 13. In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids.
    Mothe-Satney I, Gautier N, Hinault C, Lawrence JC, Van Obberghen E.
    J Biol Chem; 2004 Oct 08; 279(41):42628-37. PubMed ID: 15292249
    [Abstract] [Full Text] [Related]

  • 14. Somatostatin interferes with thyrotropin-induced G1-S transition mediated by cAMP-dependent protein kinase and phosphatidylinositol 3-kinase. Involvement of RhoA and cyclin E x cyclin-dependent kinase 2 complexes.
    Medina DL, Toro MJ, Santisteban P.
    J Biol Chem; 2000 May 19; 275(20):15549-56. PubMed ID: 10809788
    [Abstract] [Full Text] [Related]

  • 15. Distinct specificities of pRb phosphorylation by CDK4 activated by cyclin D1 or cyclin D3: differential involvement in the distinct mitogenic modes of thyroid epithelial cells.
    Paternot S, Arsenijevic T, Coulonval K, Bockstaele L, Dumont JE, Roger PP.
    Cell Cycle; 2006 Jan 19; 5(1):61-70. PubMed ID: 16294008
    [Abstract] [Full Text] [Related]

  • 16. Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A.
    Tsygankova OM, Saavedra A, Rebhun JF, Quilliam LA, Meinkoth JL.
    Mol Cell Biol; 2001 Mar 19; 21(6):1921-9. PubMed ID: 11238928
    [Abstract] [Full Text] [Related]

  • 17. Glucagon represses signaling through the mammalian target of rapamycin in rat liver by activating AMP-activated protein kinase.
    Kimball SR, Siegfried BA, Jefferson LS.
    J Biol Chem; 2004 Dec 24; 279(52):54103-9. PubMed ID: 15494402
    [Abstract] [Full Text] [Related]

  • 18. Cyclic adenosine 3',5'-monophosphate (cAMP)-dependent protein kinases, but not exchange proteins directly activated by cAMP (Epac), mediate thyrotropin/cAMP-dependent regulation of thyroid cells.
    Dremier S, Milenkovic M, Blancquaert S, Dumont JE, Døskeland SO, Maenhaut C, Roger PP.
    Endocrinology; 2007 Oct 24; 148(10):4612-22. PubMed ID: 17584967
    [Abstract] [Full Text] [Related]

  • 19. Leucine stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing mTORC1 activation.
    Suryawan A, Jeyapalan AS, Orellana RA, Wilson FA, Nguyen HV, Davis TA.
    Am J Physiol Endocrinol Metab; 2008 Oct 24; 295(4):E868-75. PubMed ID: 18682538
    [Abstract] [Full Text] [Related]

  • 20. The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1.
    Oshiro N, Takahashi R, Yoshino K, Tanimura K, Nakashima A, Eguchi S, Miyamoto T, Hara K, Takehana K, Avruch J, Kikkawa U, Yonezawa K.
    J Biol Chem; 2007 Jul 13; 282(28):20329-39. PubMed ID: 17517883
    [Abstract] [Full Text] [Related]

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