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204 related items for PubMed ID: 20506142

  • 1. Statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, function as inhibitors of cellular and molecular components involved in type I interferon production.
    Amuro H, Ito T, Miyamoto R, Sugimoto H, Torii Y, Son Y, Nakamichi N, Yamazaki C, Hoshino K, Kaisho T, Ozaki Y, Inaba M, Amakawa R, Fukuhara S.
    Arthritis Rheum; 2010 Jul; 62(7):2073-85. PubMed ID: 20506142
    [Abstract] [Full Text] [Related]

  • 2. Regulation of the interferon-alpha production induced by RNA-containing immune complexes in plasmacytoid dendritic cells.
    Eloranta ML, Lövgren T, Finke D, Mathsson L, Rönnelid J, Kastner B, Alm GV, Rönnblom L.
    Arthritis Rheum; 2009 Aug; 60(8):2418-27. PubMed ID: 19644885
    [Abstract] [Full Text] [Related]

  • 3. C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: a novel link between C1q deficiency and systemic lupus erythematosus pathogenesis.
    Lood C, Gullstrand B, Truedsson L, Olin AI, Alm GV, Rönnblom L, Sturfelt G, Eloranta ML, Bengtsson AA.
    Arthritis Rheum; 2009 Oct; 60(10):3081-90. PubMed ID: 19790049
    [Abstract] [Full Text] [Related]

  • 4. Inhibitor of IkappaB kinase activity, BAY 11-7082, interferes with interferon regulatory factor 7 nuclear translocation and type I interferon production by plasmacytoid dendritic cells.
    Miyamoto R, Ito T, Nomura S, Amakawa R, Amuro H, Katashiba Y, Ogata M, Murakami N, Shimamoto K, Yamazaki C, Hoshino K, Kaisho T, Fukuhara S.
    Arthritis Res Ther; 2010 Oct; 12(3):R87. PubMed ID: 20470398
    [Abstract] [Full Text] [Related]

  • 5. Expression of the markers BDCA-2 and BDCA-4 and production of interferon-alpha by plasmacytoid dendritic cells in systemic lupus erythematosus.
    Blomberg S, Eloranta ML, Magnusson M, Alm GV, Rönnblom L.
    Arthritis Rheum; 2003 Sep; 48(9):2524-32. PubMed ID: 13130472
    [Abstract] [Full Text] [Related]

  • 6. TLR9/TLR7-triggered downregulation of BDCA2 expression on human plasmacytoid dendritic cells from healthy individuals and lupus patients.
    Wu P, Wu J, Liu S, Han X, Lu J, Shi Y, Wang J, Lu L, Cao X.
    Clin Immunol; 2008 Oct; 129(1):40-8. PubMed ID: 18684674
    [Abstract] [Full Text] [Related]

  • 7. Trichostatin A blocks type I interferon production by activated plasmacytoid dendritic cells.
    Salvi V, Bosisio D, Mitola S, Andreoli L, Tincani A, Sozzani S.
    Immunobiology; 2010 Oct; 215(9-10):756-61. PubMed ID: 20573419
    [Abstract] [Full Text] [Related]

  • 8. Induction of interferon-alpha by immune complexes or liposomes containing systemic lupus erythematosus autoantigen- and Sjögren's syndrome autoantigen-associated RNA.
    Lövgren T, Eloranta ML, Kastner B, Wahren-Herlenius M, Alm GV, Rönnblom L.
    Arthritis Rheum; 2006 Jun; 54(6):1917-27. PubMed ID: 16729300
    [Abstract] [Full Text] [Related]

  • 9. Prostaglandin E2 inhibits IFN-alpha secretion and Th1 costimulation by human plasmacytoid dendritic cells via E-prostanoid 2 and E-prostanoid 4 receptor engagement.
    Fabricius D, Neubauer M, Mandel B, Schütz C, Viardot A, Vollmer A, Jahrsdörfer B, Debatin KM.
    J Immunol; 2010 Jan 15; 184(2):677-84. PubMed ID: 20018632
    [Abstract] [Full Text] [Related]

  • 10. Lupus-like disease and high interferon levels corresponding to trisomy of the type I interferon cluster on chromosome 9p.
    Zhuang H, Kosboth M, Lee P, Rice A, Driscoll DJ, Zori R, Narain S, Lyons R, Satoh M, Sobel E, Reeves WH.
    Arthritis Rheum; 2006 May 15; 54(5):1573-9. PubMed ID: 16645992
    [Abstract] [Full Text] [Related]

  • 11. Anti-interferon alpha treatment in SLE.
    Kirou KA, Gkrouzman E.
    Clin Immunol; 2013 Sep 15; 148(3):303-12. PubMed ID: 23566912
    [Abstract] [Full Text] [Related]

  • 12. A compass that points to lupus: genetic studies on type I interferon pathway.
    Kyogoku C, Tsuchiya N.
    Genes Immun; 2007 Sep 15; 8(6):445-55. PubMed ID: 17581625
    [Abstract] [Full Text] [Related]

  • 13. B lymphocytes enhance interferon-α production by plasmacytoid dendritic cells.
    Berggren O, Hagberg N, Weber G, Alm GV, Rönnblom L, Eloranta ML.
    Arthritis Rheum; 2012 Oct 15; 64(10):3409-19. PubMed ID: 22736048
    [Abstract] [Full Text] [Related]

  • 14. IFN-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes is promoted by NK cells via MIP-1β and LFA-1.
    Hagberg N, Berggren O, Leonard D, Weber G, Bryceson YT, Alm GV, Eloranta ML, Rönnblom L.
    J Immunol; 2011 May 01; 186(9):5085-94. PubMed ID: 21430220
    [Abstract] [Full Text] [Related]

  • 15. Bcl-2 antagonists kill plasmacytoid dendritic cells from lupus-prone mice and dampen interferon-α production.
    Zhan Y, Carrington EM, Ko HJ, Vikstrom IB, Oon S, Zhang JG, Vremec D, Brady JL, Bouillet P, Wu L, Huang DC, Wicks IP, Morand EF, Strasser A, Lew AM.
    Arthritis Rheumatol; 2015 Mar 01; 67(3):797-808. PubMed ID: 25418983
    [Abstract] [Full Text] [Related]

  • 16. Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus.
    Yao Y, Richman L, Higgs BW, Morehouse CA, de los Reyes M, Brohawn P, Zhang J, White B, Coyle AJ, Kiener PA, Jallal B.
    Arthritis Rheum; 2009 Jun 01; 60(6):1785-96. PubMed ID: 19479852
    [Abstract] [Full Text] [Related]

  • 17. Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG.
    Lövgren T, Eloranta ML, Båve U, Alm GV, Rönnblom L.
    Arthritis Rheum; 2004 Jun 01; 50(6):1861-72. PubMed ID: 15188363
    [Abstract] [Full Text] [Related]

  • 18. Simvastatin antagonizes tumor necrosis factor-alpha inhibition of bone morphogenetic proteins-2-induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway.
    Yamashita M, Otsuka F, Mukai T, Otani H, Inagaki K, Miyoshi T, Goto J, Yamamura M, Makino H.
    J Endocrinol; 2008 Mar 01; 196(3):601-13. PubMed ID: 18310456
    [Abstract] [Full Text] [Related]

  • 19. Statins inhibit cyclooxygenase-2 and matrix metalloproteinase-9 in human endothelial cells: anti-angiogenic actions possibly contributing to plaque stability.
    Massaro M, Zampolli A, Scoditti E, Carluccio MA, Storelli C, Distante A, De Caterina R.
    Cardiovasc Res; 2010 May 01; 86(2):311-20. PubMed ID: 19946014
    [Abstract] [Full Text] [Related]

  • 20. PTPN22 Variant R620W Is Associated With Reduced Toll-like Receptor 7-Induced Type I Interferon in Systemic Lupus Erythematosus.
    Wang Y, Ewart D, Crabtree JN, Yamamoto A, Baechler EC, Fazeli P, Peterson EJ.
    Arthritis Rheumatol; 2015 Sep 01; 67(9):2403-14. PubMed ID: 26018863
    [Abstract] [Full Text] [Related]

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