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302 related items for PubMed ID: 20506484

  • 1. PTEN- and p53-mediated apoptosis and cell cycle arrest by FTY720 in gastric cancer cells and nude mice.
    Zheng T, Meng X, Wang J, Chen X, Yin D, Liang Y, Song X, Pan S, Jiang H, Liu L.
    J Cell Biochem; 2010 Sep 01; 111(1):218-28. PubMed ID: 20506484
    [Abstract] [Full Text] [Related]

  • 2. FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation.
    Lee TK, Man K, Ho JW, Sun CK, Ng KT, Wang XH, Wong YC, Ng IO, Xu R, Fan ST.
    Carcinogenesis; 2004 Dec 01; 25(12):2397-405. PubMed ID: 15297371
    [Abstract] [Full Text] [Related]

  • 3. The LXR-623-induced long non-coding RNA LINC01125 suppresses the proliferation of breast cancer cells via PTEN/AKT/p53 signaling pathway.
    Wan W, Hou Y, Wang K, Cheng Y, Pu X, Ye X.
    Cell Death Dis; 2019 Mar 13; 10(3):248. PubMed ID: 30867411
    [Abstract] [Full Text] [Related]

  • 4. EF24 induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by increasing PTEN expression.
    Selvendiran K, Tong L, Vishwanath S, Bratasz A, Trigg NJ, Kutala VK, Hideg K, Kuppusamy P.
    J Biol Chem; 2007 Sep 28; 282(39):28609-28618. PubMed ID: 17684018
    [Abstract] [Full Text] [Related]

  • 5. FTY720 inhibits proliferation and epithelial-mesenchymal transition in cholangiocarcinoma by inactivating STAT3 signaling.
    Lu Z, Wang J, Zheng T, Liang Y, Yin D, Song R, Pei T, Pan S, Jiang H, Liu L.
    BMC Cancer; 2014 Oct 25; 14():783. PubMed ID: 25344679
    [Abstract] [Full Text] [Related]

  • 6. Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.
    Choi HJ, Chung TW, Kang SK, Lee YC, Ko JH, Kim JG, Kim CH.
    Glycobiology; 2006 Jul 25; 16(7):573-83. PubMed ID: 16574813
    [Abstract] [Full Text] [Related]

  • 7. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells.
    Zhang L, Wang H, Ding K, Xu J.
    Toxicol Lett; 2015 Jul 02; 236(1):43-59. PubMed ID: 25939952
    [Abstract] [Full Text] [Related]

  • 8. FTY720 induced Bcl-associated and Fas-independent apoptosis in human renal cancer cells in vitro and significantly reduced in vivo tumor growth in mouse xenograft.
    Ubai T, Azuma H, Kotake Y, Inamoto T, Takahara K, Ito Y, Kiyama S, Sakamoto T, Horie S, Muto S, Takahara S, Otsuki Y, Katsuoka Y.
    Anticancer Res; 2007 Jul 02; 27(1A):75-88. PubMed ID: 17352219
    [Abstract] [Full Text] [Related]

  • 9. EVA1A reverses lenvatinib resistance in hepatocellular carcinoma through regulating PI3K/AKT/p53 signaling axis.
    Liu X, Gao X, Yang Y, Yang D, Guo Q, Li L, Liu S, Cong W, Lu S, Hou L, Wang B, Li N.
    Apoptosis; 2024 Aug 02; 29(7-8):1161-1184. PubMed ID: 38743191
    [Abstract] [Full Text] [Related]

  • 10. FTY720 reduces migration and invasion of human glioblastoma cell lines via inhibiting the PI3K/AKT/mTOR/p70S6K signaling pathway.
    Zhang L, Wang H, Zhu J, Ding K, Xu J.
    Tumour Biol; 2014 Nov 02; 35(11):10707-14. PubMed ID: 25070489
    [Abstract] [Full Text] [Related]

  • 11. Could changes in the regulation of the PI3K/PKB/Akt signaling pathway and cell cycle be involved in astrocytic tumor pathogenesis and progression?
    Hlobilkova A, Ehrmann J, Sedlakova E, Krejci V, Knizetova P, Fiuraskova M, Kala M, Kalita O, Kolar Z.
    Neoplasma; 2007 Nov 02; 54(4):334-41. PubMed ID: 17822324
    [Abstract] [Full Text] [Related]

  • 12. Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: the role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways.
    Leu WJ, Swain ShP, Chan SH, Hsu JL, Liu SP, Chan ML, Yu CC, Hsu LC, Chou YL, Chang WL, Hou DR, Guh JH.
    Oncotarget; 2016 Nov 22; 7(47):76995-77009. PubMed ID: 27769069
    [Abstract] [Full Text] [Related]

  • 13. Influence of zinc deficiency on Akt-Mdm2-p53 and Akt-p21 signaling axes in normal and malignant human prostate cells.
    Han CT, Schoene NW, Lei KY.
    Am J Physiol Cell Physiol; 2009 Nov 22; 297(5):C1188-99. PubMed ID: 19657064
    [Abstract] [Full Text] [Related]

  • 14. A novel all-trans retinoic acid derivative 4-amino‑2‑trifluoromethyl-phenyl retinate inhibits the proliferation of human hepatocellular carcinoma HepG2 cells by inducing G0/G1 cell cycle arrest and apoptosis via upregulation of p53 and ASPP1 and downregulation of iASPP.
    Liu H, Chen F, Zhang L, Zhou Q, Gui S, Wang Y.
    Oncol Rep; 2016 Jul 22; 36(1):333-41. PubMed ID: 27177208
    [Abstract] [Full Text] [Related]

  • 15. HDACi inhibits liposarcoma via targeting of the MDM2-p53 signaling axis and PTEN, irrespective of p53 mutational status.
    Ou WB, Zhu J, Eilers G, Li X, Kuang Y, Liu L, Mariño-Enríquez A, Yan Z, Li H, Meng F, Zhou H, Sheng Q, Fletcher JA.
    Oncotarget; 2015 Apr 30; 6(12):10510-20. PubMed ID: 25888633
    [Abstract] [Full Text] [Related]

  • 16. Oroxylin A promotes PTEN-mediated negative regulation of MDM2 transcription via SIRT3-mediated deacetylation to stabilize p53 and inhibit glycolysis in wt-p53 cancer cells.
    Zhao K, Zhou Y, Qiao C, Ni T, Li Z, Wang X, Guo Q, Lu N, Wei L.
    J Hematol Oncol; 2015 Apr 23; 8():41. PubMed ID: 25902914
    [Abstract] [Full Text] [Related]

  • 17. Mechanism of the inhibition of leukemia cell growth and induction of apoptosis through the activation of ATR and PTEN by the topoisomerase inhibitor 3EZ, 20Ac-ingenol.
    Miyata S, Fukuda Y, Tojima H, Matsuzaki K, Kitanaka S, Sawada H.
    Leuk Res; 2015 Sep 23; 39(9):927-32. PubMed ID: 26194899
    [Abstract] [Full Text] [Related]

  • 18. Apoptosis induced by the methanol extract of Salvia miltiorrhiza Bunge in non-small cell lung cancer through PTEN-mediated inhibition of PI3K/Akt pathway.
    Ye YT, Zhong W, Sun P, Wang D, Wang C, Hu LM, Qian JQ.
    J Ethnopharmacol; 2017 Mar 22; 200():107-116. PubMed ID: 28088493
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of esophageal-carcinoma cell proliferation by genistein via suppression of JAK1/2-STAT3 and AKT/MDM2/p53 signaling pathways.
    Gao J, Xia R, Chen J, Gao J, Luo X, Ke C, Ren C, Li J, Mi Y.
    Aging (Albany NY); 2020 Apr 10; 12(7):6240-6259. PubMed ID: 32276266
    [Abstract] [Full Text] [Related]

  • 20. Coordinate involvement of cell cycle arrest and apoptosis strengthen the effect of FTY720.
    Nagahara Y, Matsuoka Y, Saito K, Ikekita M, Higuchi S, Shinomiya T.
    Jpn J Cancer Res; 2001 Jun 10; 92(6):680-7. PubMed ID: 11429058
    [Abstract] [Full Text] [Related]

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