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Journal Abstract Search

225 related items for PubMed ID: 20507304

  • 1. AT9283, a potent inhibitor of the Aurora kinases and Jak2, has therapeutic potential in myeloproliferative disorders.
    Dawson MA, Curry JE, Barber K, Beer PA, Graham B, Lyons JF, Richardson CJ, Scott MA, Smyth T, Squires MS, Thompson NT, Green AR, Wallis NG.
    Br J Haematol; 2010 Jul; 150(1):46-57. PubMed ID: 20507304
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  • 2. AT9283, a novel aurora kinase inhibitor, suppresses tumor growth in aggressive B-cell lymphomas.
    Qi W, Liu X, Cooke LS, Persky DO, Miller TP, Squires M, Mahadevan D.
    Int J Cancer; 2012 Jun 15; 130(12):2997-3005. PubMed ID: 21796626
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  • 10. TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations.
    Pardanani A, Hood J, Lasho T, Levine RL, Martin MB, Noronha G, Finke C, Mak CC, Mesa R, Zhu H, Soll R, Gilliland DG, Tefferi A.
    Leukemia; 2007 Aug 15; 21(8):1658-68. PubMed ID: 17541402
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  • 11. Aurora kinase inhibitors as anti-cancer therapy.
    Lok W, Klein RQ, Saif MW.
    Anticancer Drugs; 2010 Apr 15; 21(4):339-50. PubMed ID: 20016367
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  • 12. WP1066, a novel JAK2 inhibitor, suppresses proliferation and induces apoptosis in erythroid human cells carrying the JAK2 V617F mutation.
    Verstovsek S, Manshouri T, Quintás-Cardama A, Harris D, Cortes J, Giles FJ, Kantarjian H, Priebe W, Estrov Z.
    Clin Cancer Res; 2008 Feb 01; 14(3):788-96. PubMed ID: 18245540
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  • 17. Discovery and evaluation of ZT55, a novel highly-selective tyrosine kinase inhibitor of JAK2V617F against myeloproliferative neoplasms.
    Hu M, Xu C, Yang C, Zuo H, Chen C, Zhang D, Shi G, Wang W, Shi J, Zhang T.
    J Exp Clin Cancer Res; 2019 Feb 04; 38(1):49. PubMed ID: 30717771
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  • 18. JAK2 V617F uses distinct signalling pathways to induce cell proliferation and neutrophil activation.
    Oku S, Takenaka K, Kuriyama T, Shide K, Kumano T, Kikushige Y, Urata S, Yamauchi T, Iwamoto C, Shimoda HK, Miyamoto T, Nagafuji K, Kishimoto J, Shimoda K, Akashi K.
    Br J Haematol; 2010 Aug 04; 150(3):334-44. PubMed ID: 20553273
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  • 19. AT9283 exhibits antiproliferative effect on tyrosine kinase inhibitor‑sensitive and ‑resistant chronic myeloid leukemia cells by inhibition of Aurora A and Aurora B.
    Takeda T, Tsubaki M, Genno S, Nemoto C, Onishi Y, Yamamoto Y, Imano M, Satou T, Nishida S.
    Oncol Rep; 2020 Nov 04; 44(5):2211-2218. PubMed ID: 33000229
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  • 20. The HDAC inhibitor Givinostat modulates the hematopoietic transcription factors NFE2 and C-MYB in JAK2(V617F) myeloproliferative neoplasm cells.
    Amaru Calzada A, Todoerti K, Donadoni L, Pellicioli A, Tuana G, Gatta R, Neri A, Finazzi G, Mantovani R, Rambaldi A, Introna M, Lombardi L, Golay J, AGIMM Investigators.
    Exp Hematol; 2012 Aug 04; 40(8):634-45.e10. PubMed ID: 22579713
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