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298 related items for PubMed ID: 20515468

  • 1. pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking.
    Pardo R, Molina-Calavita M, Poizat G, Keryer G, Humbert S, Saudou F.
    Mol Brain; 2010 Jun 01; 3():17. PubMed ID: 20515468
    [Abstract] [Full Text] [Related]

  • 2. Mutant Huntingtin alters retrograde transport of TrkB receptors in striatal dendrites.
    Liot G, Zala D, Pla P, Mottet G, Piel M, Saudou F.
    J Neurosci; 2013 Apr 10; 33(15):6298-309. PubMed ID: 23575829
    [Abstract] [Full Text] [Related]

  • 3. Huntingtin facilitates dynein/dynactin-mediated vesicle transport.
    Caviston JP, Ross JL, Antony SM, Tokito M, Holzbaur EL.
    Proc Natl Acad Sci U S A; 2007 Jun 12; 104(24):10045-50. PubMed ID: 17548833
    [Abstract] [Full Text] [Related]

  • 4. Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons.
    Zala D, Colin E, Rangone H, Liot G, Humbert S, Saudou F.
    Hum Mol Genet; 2008 Dec 15; 17(24):3837-46. PubMed ID: 18772195
    [Abstract] [Full Text] [Related]

  • 5. The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation.
    Wong YC, Holzbaur EL.
    J Neurosci; 2014 Jan 22; 34(4):1293-305. PubMed ID: 24453320
    [Abstract] [Full Text] [Related]

  • 6. [Huntington's disease: intracellular signaling pathways and neuronal death].
    Humbert S, Saudou F.
    J Soc Biol; 2005 Jan 22; 199(3):247-51. PubMed ID: 16471265
    [Abstract] [Full Text] [Related]

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  • 8. Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes.
    Caviston JP, Zajac AL, Tokito M, Holzbaur EL.
    Mol Biol Cell; 2011 Feb 15; 22(4):478-92. PubMed ID: 21169558
    [Abstract] [Full Text] [Related]

  • 9. Mutant huntingtin impairs the post-Golgi trafficking of brain-derived neurotrophic factor but not its Val66Met polymorphism.
    del Toro D, Canals JM, Ginés S, Kojima M, Egea G, Alberch J.
    J Neurosci; 2006 Dec 06; 26(49):12748-57. PubMed ID: 17151278
    [Abstract] [Full Text] [Related]

  • 10. Inducing huntingtin inclusion formation in primary neuronal cell culture and in vivo by high-capacity adenoviral vectors expressing truncated and full-length huntingtin with polyglutamine expansion.
    Huang B, Schiefer J, Sass C, Kosinski CM, Kochanek S.
    J Gene Med; 2008 Mar 06; 10(3):269-79. PubMed ID: 18067195
    [Abstract] [Full Text] [Related]

  • 11. PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD).
    Ratovitski T, Arbez N, Stewart JC, Chighladze E, Ross CA.
    Cell Cycle; 2015 Mar 06; 14(11):1716-29. PubMed ID: 25927346
    [Abstract] [Full Text] [Related]

  • 12. Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice.
    Zheng S, Clabough EB, Sarkar S, Futter M, Rubinsztein DC, Zeitlin SO.
    PLoS Genet; 2010 Feb 05; 6(2):e1000838. PubMed ID: 20140187
    [Abstract] [Full Text] [Related]

  • 13. Adenovirus vector-based in vitro neuronal cell model for Huntington's disease with human disease-like differential aggregation and degeneration.
    Dong X, Zong S, Witting A, Lindenberg KS, Kochanek S, Huang B.
    J Gene Med; 2012 Jul 05; 14(7):468-81. PubMed ID: 22700462
    [Abstract] [Full Text] [Related]

  • 14. Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
    Gauthier LR, Charrin BC, Borrell-Pagès M, Dompierre JP, Rangone H, Cordelières FP, De Mey J, MacDonald ME, Lessmann V, Humbert S, Saudou F.
    Cell; 2004 Jul 09; 118(1):127-38. PubMed ID: 15242649
    [Abstract] [Full Text] [Related]

  • 15. Native mutant huntingtin in human brain: evidence for prevalence of full-length monomer.
    Sapp E, Valencia A, Li X, Aronin N, Kegel KB, Vonsattel JP, Young AB, Wexler N, DiFiglia M.
    J Biol Chem; 2012 Apr 13; 287(16):13487-99. PubMed ID: 22375012
    [Abstract] [Full Text] [Related]

  • 16. Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease.
    Busch A, Engemann S, Lurz R, Okazawa H, Lehrach H, Wanker EE.
    J Biol Chem; 2003 Oct 17; 278(42):41452-61. PubMed ID: 12888569
    [Abstract] [Full Text] [Related]

  • 17. N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking.
    Orr AL, Li S, Wang CE, Li H, Wang J, Rong J, Xu X, Mastroberardino PG, Greenamyre JT, Li XJ.
    J Neurosci; 2008 Mar 12; 28(11):2783-92. PubMed ID: 18337408
    [Abstract] [Full Text] [Related]

  • 18. Huntingtin-mediated axonal transport requires arginine methylation by PRMT6.
    Migazzi A, Scaramuzzino C, Anderson EN, Tripathy D, Hernández IH, Grant RA, Roccuzzo M, Tosatto L, Virlogeux A, Zuccato C, Caricasole A, Ratovitski T, Ross CA, Pandey UB, Lucas JJ, Saudou F, Pennuto M, Basso M.
    Cell Rep; 2021 Apr 13; 35(2):108980. PubMed ID: 33852844
    [Abstract] [Full Text] [Related]

  • 19. Effects of overexpression of huntingtin proteins on mitochondrial integrity.
    Wang H, Lim PJ, Karbowski M, Monteiro MJ.
    Hum Mol Genet; 2009 Feb 15; 18(4):737-52. PubMed ID: 19039036
    [Abstract] [Full Text] [Related]

  • 20. Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease.
    Zhang H, Li Q, Graham RK, Slow E, Hayden MR, Bezprozvanny I.
    Neurobiol Dis; 2008 Jul 15; 31(1):80-8. PubMed ID: 18502655
    [Abstract] [Full Text] [Related]

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