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Journal Abstract Search

221 related items for PubMed ID: 20530407

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  • 4. In vivo efficacy of recombinant methioninase is enhanced by the combination of polyethylene glycol conjugation and pyridoxal 5'-phosphate supplementation.
    Sun X, Yang Z, Li S, Tan Y, Zhang N, Wang X, Yagi S, Yoshioka T, Takimoto A, Mitsushima K, Suginaka A, Frenkel EP, Hoffman RM.
    Cancer Res; 2003 Dec 01; 63(23):8377-83. PubMed ID: 14678999
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  • 7. Polyethylene glycol conjugation of recombinant methioninase for cancer therapy.
    Tan Y, Sun X, Xu M, An Z, Tan X, Han Q, Miljkovic DA, Yang M, Hoffman RM.
    Protein Expr Purif; 1998 Feb 01; 12(1):45-52. PubMed ID: 9473456
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  • 8. Overexpression and large-scale production of recombinant L-methionine-alpha-deamino-gamma-mercaptomethane-lyase for novel anticancer therapy.
    Tan Y, Xu M, Tan X, Tan X, Wang X, Saikawa Y, Nagahama T, Sun X, Lenz M, Hoffman RM.
    Protein Expr Purif; 1997 Mar 01; 9(2):233-45. PubMed ID: 9056489
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  • 9. Circulating half-life of PEGylated recombinant methioninase holoenzyme is highly dose dependent on cofactor pyridoxal-5'-phosphate.
    Yang Z, Sun X, Li S, Tan Y, Wang X, Zhang N, Yagi S, Takakura T, Kobayashi Y, Takimoto A, Yoshioka T, Suginaka A, Frenkel EP, Hoffman RM.
    Cancer Res; 2004 Aug 15; 64(16):5775-8. PubMed ID: 15313919
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  • 10. PEGylation confers greatly extended half-life and attenuated immunogenicity to recombinant methioninase in primates.
    Yang Z, Wang J, Lu Q, Xu J, Kobayashi Y, Takakura T, Takimoto A, Yoshioka T, Lian C, Chen C, Zhang D, Zhang Y, Li S, Sun X, Tan Y, Yagi S, Frenkel EP, Hoffman RM.
    Cancer Res; 2004 Sep 15; 64(18):6673-8. PubMed ID: 15374983
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  • 11. Methioninase gene therapy of human cancer cells is synergistic with recombinant methioninase treatment.
    Miki K, Al-Refaie W, Xu M, Jiang P, Tan Y, Bouvet M, Zhao M, Gupta A, Chishima T, Shimada H, Makuuchi M, Moossa AR, Hoffman RM.
    Cancer Res; 2000 May 15; 60(10):2696-702. PubMed ID: 10825143
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  • 12. Recombinant methioninase infusion reduces the biochemical endpoint of serum methionine with minimal toxicity in high-stage cancer patients.
    Tan Y, Zavala J, Han Q, Xu M, Sun X, Tan X, Tan X, Magana R, Geller J, Hoffman RM.
    Anticancer Res; 1997 May 15; 17(5B):3857-60. PubMed ID: 9427792
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  • 18. Effective Metabolic Targeting of Human Osteosarcoma Cells In Vitro and in Orthotopic Nude-mouse Models with Recombinant Methioninase.
    Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Murakami T, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Hoffman RM.
    Anticancer Res; 2017 Sep 15; 37(9):4807-4812. PubMed ID: 28870899
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  • 19. Afterword: Oral Methioninase-Answer to Cancer and Fountain of Youth?
    Hoffman RM, Han Q, Kawaguchi K, Li S, Tan Y.
    Methods Mol Biol; 2019 Sep 15; 1866():311-322. PubMed ID: 30725426
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  • 20. Development of recombinant methioninase to target the general cancer-specific metabolic defect of methionine dependence: a 40-year odyssey.
    Hoffman RM.
    Expert Opin Biol Ther; 2015 Jan 15; 15(1):21-31. PubMed ID: 25439528
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