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395 related items for PubMed ID: 20533993
1. Repeated administration of alpha7 nicotinic acetylcholine receptor (nAChR) agonists, but not positive allosteric modulators, increases alpha7 nAChR levels in the brain. Christensen DZ, Mikkelsen JD, Hansen HH, Thomsen MS. J Neurochem; 2010 Aug; 114(4):1205-16. PubMed ID: 20533993 [Abstract] [Full Text] [Related]
3. Type I and II positive allosteric modulators differentially modulate agonist-induced up-regulation of α7 nicotinic acetylcholine receptors. Thomsen MS, Mikkelsen JD. J Neurochem; 2012 Oct; 123(1):73-83. PubMed ID: 22804734 [Abstract] [Full Text] [Related]
4. Alpha7 nAChR-mediated activation of MAP kinase pathways in PC12 cells. Gubbins EJ, Gopalakrishnan M, Li J. Brain Res; 2010 Apr 30; 1328():1-11. PubMed ID: 20211606 [Abstract] [Full Text] [Related]
5. Differential immediate and sustained memory enhancing effects of alpha7 nicotinic receptor agonists and allosteric modulators in rats. Thomsen MS, El-Sayed M, Mikkelsen JD. PLoS One; 2011 Apr 30; 6(11):e27014. PubMed ID: 22096516 [Abstract] [Full Text] [Related]
6. Differential coupling of alpha7 and non-alpha7 nicotinic acetylcholine receptors to calcium-induced calcium release and voltage-operated calcium channels in PC12 cells. Dickinson JA, Hanrott KE, Mok MH, Kew JN, Wonnacott S. J Neurochem; 2007 Feb 30; 100(4):1089-96. PubMed ID: 17181555 [Abstract] [Full Text] [Related]
7. In vitro pharmacological characterization of a novel allosteric modulator of alpha 7 neuronal acetylcholine receptor, 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744), exhibiting unique pharmacological profile. Malysz J, Grønlien JH, Anderson DJ, Håkerud M, Thorin-Hagene K, Ween H, Wetterstrand C, Briggs CA, Faghih R, Bunnelle WH, Gopalakrishnan M. J Pharmacol Exp Ther; 2009 Jul 30; 330(1):257-67. PubMed ID: 19389923 [Abstract] [Full Text] [Related]
8. In vitro pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107. Malysz J, Anderson DJ, Grønlien JH, Ji J, Bunnelle WH, Håkerud M, Thorin-Hagene K, Ween H, Helfrich R, Hu M, Gubbins E, Gopalakrishnan S, Puttfarcken PS, Briggs CA, Li J, Meyer MD, Dyhring T, Ahring PK, Nielsen EØ, Peters D, Timmermann DB, Gopalakrishnan M. J Pharmacol Exp Ther; 2010 Sep 01; 334(3):863-74. PubMed ID: 20504915 [Abstract] [Full Text] [Related]
9. An allosteric modulator of the alpha7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo. Timmermann DB, Grønlien JH, Kohlhaas KL, Nielsen EØ, Dam E, Jørgensen TD, Ahring PK, Peters D, Holst D, Christensen JK, Malysz J, Briggs CA, Gopalakrishnan M, Olsen GM. J Pharmacol Exp Ther; 2007 Oct 01; 323(1):294-307. PubMed ID: 17625074 [Abstract] [Full Text] [Related]
10. Pharmacological characterization of [(125)I]CHIBA-1006 binding, a new radioligand for α7 nicotinic acetylcholine receptors, to rat brain membranes. Wu J, Toyohara J, Tanibuchi Y, Fujita Y, Zhang J, Chen H, Matsuo M, Wang RF, Hashimoto K. Brain Res; 2010 Nov 11; 1360():130-7. PubMed ID: 20816767 [Abstract] [Full Text] [Related]
11. JN403, in vitro characterization of a novel nicotinic acetylcholine receptor alpha7 selective agonist. Feuerbach D, Nozulak J, Lingenhoehl K, McAllister K, Hoyer D. Neurosci Lett; 2007 Apr 06; 416(1):61-5. PubMed ID: 17314009 [Abstract] [Full Text] [Related]
12. Positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor: ligand interactions with distinct binding sites and evidence for a prominent role of the M2-M3 segment. Bertrand D, Bertrand S, Cassar S, Gubbins E, Li J, Gopalakrishnan M. Mol Pharmacol; 2008 Nov 06; 74(5):1407-16. PubMed ID: 18678621 [Abstract] [Full Text] [Related]
13. In vivo pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107: preclinical considerations in Alzheimer's disease. Bitner RS, Bunnelle WH, Decker MW, Drescher KU, Kohlhaas KL, Markosyan S, Marsh KC, Nikkel AL, Browman K, Radek R, Anderson DJ, Buccafusco J, Gopalakrishnan M. J Pharmacol Exp Ther; 2010 Sep 01; 334(3):875-86. PubMed ID: 20504913 [Abstract] [Full Text] [Related]
14. Presynaptic alpha 7- and beta 2-containing nicotinic acetylcholine receptors modulate excitatory amino acid release from rat prefrontal cortex nerve terminals via distinct cellular mechanisms. Dickinson JA, Kew JN, Wonnacott S. Mol Pharmacol; 2008 Aug 01; 74(2):348-59. PubMed ID: 18445710 [Abstract] [Full Text] [Related]
15. Alpha 7 nicotinic receptor agonist and positive allosteric modulators improved social and molecular deficits of MK-801 model of schizophrenia in rats. Unal G, Bekci H, Cumaoglu A, Yerer MB, Aricioglu F. Pharmacol Biochem Behav; 2020 Jun 01; 193():172916. PubMed ID: 32220620 [Abstract] [Full Text] [Related]
16. Chronic nicotine and dizocilpine effects on regionally specific nicotinic and NMDA glutamate receptor binding. Levin ED, Tizabi Y, Rezvani AH, Caldwell DP, Petro A, Getachew B. Brain Res; 2005 Apr 18; 1041(2):132-42. PubMed ID: 15829222 [Abstract] [Full Text] [Related]
17. Non-neuronal nicotinic alpha 7 receptor, a new endothelial target for revascularization. Li XW, Wang H. Life Sci; 2006 Mar 13; 78(16):1863-70. PubMed ID: 16280133 [Abstract] [Full Text] [Related]
18. The consequences of reducing expression of the alpha7 nicotinic receptor by RNA interference and of stimulating its activity with an alpha7 agonist in SH-SY5Y cells indicate that this receptor plays a neuroprotective role in connection with the pathogenesis of Alzheimer's disease. Qi XL, Nordberg A, Xiu J, Guan ZZ. Neurochem Int; 2007 Mar 13; 51(6-7):377-83. PubMed ID: 17493709 [Abstract] [Full Text] [Related]
19. α7 nicotinic receptor agonism mitigates phencyclidine-induced changes in synaptophysin and Arc gene expression in the mouse prefrontal cortex. Thomsen MS, Hansen HH, Mikkelsen JD. Neurochem Int; 2010 Dec 13; 57(7):756-61. PubMed ID: 20817066 [Abstract] [Full Text] [Related]
20. Functional characterization and high-throughput screening of positive allosteric modulators of α7 nicotinic acetylcholine receptors in IMR-32 neuroblastoma cells. Gopalakrishnan SM, Philip BM, Gronlien JH, Malysz J, Anderson DJ, Gopalakrishnan M, Warrior U, Burns DJ. Assay Drug Dev Technol; 2011 Dec 13; 9(6):635-45. PubMed ID: 21309712 [Abstract] [Full Text] [Related] Page: [Next] [New Search]