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Journal Abstract Search

221 related items for PubMed ID: 20534000

  • 1. Low-dose bafilomycin attenuates neuronal cell death associated with autophagy-lysosome pathway dysfunction.
    Pivtoraiko VN, Harrington AJ, Mader BJ, Luker AM, Caldwell GA, Caldwell KA, Roth KA, Shacka JJ.
    J Neurochem; 2010 Aug; 114(4):1193-204. PubMed ID: 20534000
    [Abstract] [Full Text] [Related]

  • 2. ATP6V0C knockdown in neuroblastoma cells alters autophagy-lysosome pathway function and metabolism of proteins that accumulate in neurodegenerative disease.
    Mangieri LR, Mader BJ, Thomas CE, Taylor CA, Luker AM, Tse TE, Huisingh C, Shacka JJ.
    PLoS One; 2014 Aug; 9(4):e93257. PubMed ID: 24695574
    [Abstract] [Full Text] [Related]

  • 3. Bafilomycin A1 inhibits chloroquine-induced death of cerebellar granule neurons.
    Shacka JJ, Klocke BJ, Shibata M, Uchiyama Y, Datta G, Schmidt RE, Roth KA.
    Mol Pharmacol; 2006 Apr; 69(4):1125-36. PubMed ID: 16391239
    [Abstract] [Full Text] [Related]

  • 4. 6-Hydroxydopamine induces autophagic flux dysfunction by impairing transcription factor EB activation and lysosomal function in dopaminergic neurons and SH-SY5Y cells.
    He X, Yuan W, Li Z, Hou Y, Liu F, Feng J.
    Toxicol Lett; 2018 Feb; 283():58-68. PubMed ID: 29170033
    [Abstract] [Full Text] [Related]

  • 5. Chloroquine and bafilomycin A mimic lysosomal storage disorders and impair mTORC1 signalling.
    Fedele AO, Proud CG.
    Biosci Rep; 2020 Apr 30; 40(4):. PubMed ID: 32285908
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  • 9. Over-expression of an inactive mutant cathepsin D increases endogenous alpha-synuclein and cathepsin B activity in SH-SY5Y cells.
    Crabtree D, Dodson M, Ouyang X, Boyer-Guittaut M, Liang Q, Ballestas ME, Fineberg N, Zhang J.
    J Neurochem; 2014 Mar 30; 128(6):950-61. PubMed ID: 24138030
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  • 11. Rotenone inhibits autophagic flux prior to inducing cell death.
    Mader BJ, Pivtoraiko VN, Flippo HM, Klocke BJ, Roth KA, Mangieri LR, Shacka JJ.
    ACS Chem Neurosci; 2012 Dec 19; 3(12):1063-72. PubMed ID: 23259041
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  • 13. Boosting chaperone-mediated autophagy in vivo mitigates α-synuclein-induced neurodegeneration.
    Xilouri M, Brekk OR, Landeck N, Pitychoutis PM, Papasilekas T, Papadopoulou-Daifoti Z, Kirik D, Stefanis L.
    Brain; 2013 Jul 19; 136(Pt 7):2130-46. PubMed ID: 23757764
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  • 14. Lysosome Inhibitors Enhance the Chemotherapeutic Activity of Doxorubicin in HepG2 Cells.
    Li Y, Sun Y, Jing L, Wang J, Yan Y, Feng Y, Zhang Y, Liu Z, Ma L, Diao A.
    Chemotherapy; 2017 Jul 19; 62(2):85-93. PubMed ID: 27764836
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  • 15. Fibrillar α-synuclein toxicity depends on functional lysosomes.
    Guiney SJ, Adlard PA, Lei P, Mawal CH, Bush AI, Finkelstein DI, Ayton S.
    J Biol Chem; 2020 Dec 18; 295(51):17497-17513. PubMed ID: 33453994
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  • 16. Autophagy protects neuron from Abeta-induced cytotoxicity.
    Hung SY, Huang WP, Liou HC, Fu WM.
    Autophagy; 2009 May 18; 5(4):502-10. PubMed ID: 19270530
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  • 17. A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis.
    Sharma G, Guardia CM, Roy A, Vassilev A, Saric A, Griner LN, Marugan J, Ferrer M, Bonifacino JS, DePamphilis ML.
    Autophagy; 2019 Oct 18; 15(10):1694-1718. PubMed ID: 30806145
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  • 18. Bafilomycin A1 disrupts autophagic flux by inhibiting both V-ATPase-dependent acidification and Ca-P60A/SERCA-dependent autophagosome-lysosome fusion.
    Mauvezin C, Neufeld TP.
    Autophagy; 2015 Oct 18; 11(8):1437-8. PubMed ID: 26156798
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  • 19. Triptolide Promotes the Clearance of α-Synuclein by Enhancing Autophagy in Neuronal Cells.
    Hu G, Gong X, Wang L, Liu M, Liu Y, Fu X, Wang W, Zhang T, Wang X.
    Mol Neurobiol; 2017 Apr 18; 54(3):2361-2372. PubMed ID: 26957304
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