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580 related items for PubMed ID: 20534739

  • 21. The synergistic antitumor activity of arsenic trioxide and vitamin K2 in HL-60 cells involves increased ROS generation and regulation of the ROS-dependent MAPK signaling pathway.
    Qu H, Tong D, Zhang Y, Kang K, Zhang Y, Chen L, Ren L.
    Pharmazie; 2013 Oct; 68(10):839-45. PubMed ID: 24273890
    [Abstract] [Full Text] [Related]

  • 22. Ethacrynic acid and a derivative enhance apoptosis in arsenic trioxide-treated myeloid leukemia and lymphoma cells: the role of glutathione S-transferase p1-1.
    Wang R, Liu C, Xia L, Zhao G, Gabrilove J, Waxman S, Jing Y.
    Clin Cancer Res; 2012 Dec 15; 18(24):6690-701. PubMed ID: 23082001
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  • 23. Genistein selectively potentiates arsenic trioxide-induced apoptosis in human leukemia cells via reactive oxygen species generation and activation of reactive oxygen species-inducible protein kinases (p38-MAPK, AMPK).
    Sánchez Y, Amrán D, Fernández C, de Blas E, Aller P.
    Int J Cancer; 2008 Sep 01; 123(5):1205-14. PubMed ID: 18546268
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  • 24. Transcriptomic analysis of the PI3K/Akt signaling pathway reveals the dual role of the c-Jun oncogene in cytotoxicity and the development of resistance in HL-60 leukemia cells in response to arsenic trioxide.
    Roszak J, Smok-Pieniążek A, Stępnik M.
    Adv Clin Exp Med; 2017 Dec 01; 26(9):1335-1342. PubMed ID: 29442453
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  • 25. VS-5584 as a PI3K/mTOR inhibitor enhances apoptotic effects of subtoxic dose arsenic trioxide via inhibition of NF-κB activity in B cell precursor-acute lymphoblastic leukemia.
    Toosi B, Zaker F, Alikarami F, Kazemi A, Teremmahi Ardestanii M.
    Biomed Pharmacother; 2018 Jun 01; 102():428-437. PubMed ID: 29574283
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  • 26. Potentiation of arsenic trioxide-induced apoptosis by 8-bromo-7-methoxychrysin in human leukemia cells involves depletion of intracellular reduced glutathione.
    Xiao G, Tang X, Yao C, Wang C.
    Acta Biochim Biophys Sin (Shanghai); 2011 Sep 01; 43(9):712-21. PubMed ID: 21785114
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  • 27. A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells.
    Cuní S, Pérez-Aciego P, Pérez-Chacón G, Vargas JA, Sánchez A, Martín-Saavedra FM, Ballester S, García-Marco J, Jordá J, Durántez A.
    Leukemia; 2004 Aug 01; 18(8):1391-400. PubMed ID: 15175625
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  • 28. Effect of phosphatase and tensin homology deleted on chromosome 10 (PTEN) gene transfection on reversal of multidrug resistance in K562/ADM cells.
    Cheng Z, Yang N, Liang W, Yan X, Li L, Pan L.
    Leuk Lymphoma; 2012 Jul 01; 53(7):1383-9. PubMed ID: 22185283
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  • 29. Cardioprotective effect of salvianolic acid B against arsenic trioxide-induced injury in cardiac H9c2 cells via the PI3K/Akt signal pathway.
    Wang M, Sun GB, Sun X, Wang HW, Meng XB, Qin M, Sun J, Luo Y, Sun XB.
    Toxicol Lett; 2013 Feb 04; 216(2-3):100-7. PubMed ID: 23201927
    [Abstract] [Full Text] [Related]

  • 30. The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism.
    Chiarini F, Del Sole M, Mongiorgi S, Gaboardi GC, Cappellini A, Mantovani I, Follo MY, McCubrey JA, Martelli AM.
    Leukemia; 2008 Jun 04; 22(6):1106-16. PubMed ID: 18385752
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  • 31. Tetraarsenic hexoxide induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt suppression and p38 MAPK activation in SW620 human colon cancer cells.
    Nagappan A, Lee WS, Yun JW, Lu JN, Chang SH, Jeong JH, Kim GS, Jung JM, Hong SC.
    PLoS One; 2017 Jun 04; 12(3):e0174591. PubMed ID: 28355296
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  • 32. Arsenic trioxide induces autophagy and apoptosis in human glioma cells in vitro and in vivo through downregulation of survivin.
    Chiu HW, Ho YS, Wang YJ.
    J Mol Med (Berl); 2011 Sep 04; 89(9):927-41. PubMed ID: 21594580
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  • 33. 2-Deoxy-D-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways.
    Estañ MC, Calviño E, de Blas E, Boyano-Adánez Mdel C, Mena ML, Gómez-Gómez M, Rial E, Aller P.
    Biochem Pharmacol; 2012 Dec 15; 84(12):1604-16. PubMed ID: 23041229
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  • 34. ON 01910.Na is selectively cytotoxic for chronic lymphocytic leukemia cells through a dual mechanism of action involving PI3K/AKT inhibition and induction of oxidative stress.
    Chapman CM, Sun X, Roschewski M, Aue G, Farooqui M, Stennett L, Gibellini F, Arthur D, Pérez-Galán P, Wiestner A.
    Clin Cancer Res; 2012 Apr 01; 18(7):1979-91. PubMed ID: 22351695
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  • 35. The effect of MAPK inhibitors on arsenic trioxide-treated Calu-6 lung cells in relation to cell death, ROS and GSH levels.
    Han YH, Moon HJ, You BR, Kim SZ, Kim SH, Park WH.
    Anticancer Res; 2009 Oct 01; 29(10):3837-44. PubMed ID: 19846917
    [Abstract] [Full Text] [Related]

  • 36. Downregulation of Mcl-1 through GSK-3β activation contributes to arsenic trioxide-induced apoptosis in acute myeloid leukemia cells.
    Wang R, Xia L, Gabrilove J, Waxman S, Jing Y.
    Leukemia; 2013 Feb 01; 27(2):315-24. PubMed ID: 22751450
    [Abstract] [Full Text] [Related]

  • 37. Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH2-terminal kinase and up-regulation of death receptors.
    Chen D, Chan R, Waxman S, Jing Y.
    Cancer Res; 2006 Dec 01; 66(23):11416-23. PubMed ID: 17145888
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  • 38. Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
    Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ.
    Eur J Pharmacol; 2007 Jun 01; 563(1-3):49-60. PubMed ID: 17341418
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  • 39. Response of non-small cell lung cancer cells to the inhibitors of phosphatidylinositol 3-kinase/Akt- and MAPK kinase 4/c-Jun NH2-terminal kinase pathways: an effective therapeutic strategy for lung cancer.
    Lee HY, Oh SH, Suh YA, Baek JH, Papadimitrakopoulou V, Huang S, Hong WK.
    Clin Cancer Res; 2005 Aug 15; 11(16):6065-74. PubMed ID: 16115952
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  • 40. Suppression of TG-interacting factor sensitizes arsenic trioxide-induced apoptosis in human hepatocellular carcinoma cells.
    Liu ZM, Tseng JT, Hong DY, Huang HS.
    Biochem J; 2011 Sep 01; 438(2):349-58. PubMed ID: 21649584
    [Abstract] [Full Text] [Related]

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