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Journal Abstract Search

166 related items for PubMed ID: 20538722

  • 1. Estimation of transporters involved in the hepatobiliary transport of TA-0201CA using sandwich-cultured rat hepatocytes from normal and multidrug resistance-associated protein 2-deficient rats.
    Fukuda H, Ohashi R, Ohashi N, Yabuuchi H, Tamai I.
    Drug Metab Dispos; 2010 Sep; 38(9):1505-13. PubMed ID: 20538722
    [Abstract] [Full Text] [Related]

  • 2. Hepatobiliary transport kinetics of HSR-903, a new quinolone antibacterial agent.
    Murata M, Tamai I, Sai Y, Nagata O, Kato H, Sugiyama Y, Tsuji A.
    Drug Metab Dispos; 1998 Nov; 26(11):1113-9. PubMed ID: 9806954
    [Abstract] [Full Text] [Related]

  • 3. Biliary efflux transporters involved in the clearance of rosuvastatin in sandwich culture of primary rat hepatocytes.
    Jemnitz K, Veres Z, Tugyi R, Vereczkey L.
    Toxicol In Vitro; 2010 Mar; 24(2):605-10. PubMed ID: 19853032
    [Abstract] [Full Text] [Related]

  • 4. Effect of plasma protein binding on in vitro-in vivo correlation of biliary excretion of drugs evaluated by sandwich-cultured rat hepatocytes.
    Fukuda H, Ohashi R, Tsuda-Tsukimoto M, Tamai I.
    Drug Metab Dispos; 2008 Jul; 36(7):1275-82. PubMed ID: 18388177
    [Abstract] [Full Text] [Related]

  • 5. Culture period-dependent changes in the uptake of transporter substrates in sandwich-cultured rat and human hepatocytes.
    Kotani N, Maeda K, Watanabe T, Hiramatsu M, Gong LK, Bi YA, Takezawa T, Kusuhara H, Sugiyama Y.
    Drug Metab Dispos; 2011 Sep; 39(9):1503-10. PubMed ID: 21673128
    [Abstract] [Full Text] [Related]

  • 6. Fasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver Injury.
    Li X, Zhong K, Guo Z, Zhong D, Chen X.
    Drug Metab Dispos; 2015 Nov; 43(11):1751-9. PubMed ID: 26276582
    [Abstract] [Full Text] [Related]

  • 7. Evaluation of Oatp and Mrp2 activities in hepatobiliary excretion using newly developed positron emission tomography tracer [11C]dehydropravastatin in rats.
    Shingaki T, Takashima T, Ijuin R, Zhang X, Onoue T, Katayama Y, Okauchi T, Hayashinaka E, Cui Y, Wada Y, Suzuki M, Maeda K, Kusuhara H, Sugiyama Y, Watanabe Y.
    J Pharmacol Exp Ther; 2013 Oct; 347(1):193-202. PubMed ID: 23926287
    [Abstract] [Full Text] [Related]

  • 8. Identification of the transporters involved in the hepatobiliary transport and intestinal efflux of methyl 1-(3,4-dimethoxyphenyl)-3-(3-ethylvaleryl)-4-hydroxy-6,7,8-trimethoxy-2-naphthoate (S-8921) glucuronide, a pharmacologically active metabolite of S-8921.
    Sakamoto S, Kusuhara H, Horie K, Takahashi K, Baba T, Ishizaki J, Sugiyama Y.
    Drug Metab Dispos; 2008 Aug; 36(8):1553-61. PubMed ID: 18474677
    [Abstract] [Full Text] [Related]

  • 9. Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.
    Ho RH, Tirona RG, Leake BF, Glaeser H, Lee W, Lemke CJ, Wang Y, Kim RB.
    Gastroenterology; 2006 May; 130(6):1793-806. PubMed ID: 16697742
    [Abstract] [Full Text] [Related]

  • 10. Mechanism of the tissue distribution and biliary excretion of the cyclic peptide octreotide.
    Yamada T, Niinuma K, Lemaire M, Terasaki T, Sugiyama Y.
    J Pharmacol Exp Ther; 1996 Dec; 279(3):1357-64. PubMed ID: 8968360
    [Abstract] [Full Text] [Related]

  • 11. OATP1B1, OATP1B3, and mrp2 are involved in hepatobiliary transport of olmesartan, a novel angiotensin II blocker.
    Nakagomi-Hagihara R, Nakai D, Kawai K, Yoshigae Y, Tokui T, Abe T, Ikeda T.
    Drug Metab Dispos; 2006 May; 34(5):862-9. PubMed ID: 16501004
    [Abstract] [Full Text] [Related]

  • 12. Alpha-naphthylisothiocyanate modulates hepatobiliary transporters in sandwich-cultured rat hepatocytes.
    Guo C, He L, Yao D, A J, Cao B, Ren J, Wang G, Pan G.
    Toxicol Lett; 2014 Jan 03; 224(1):93-100. PubMed ID: 24120425
    [Abstract] [Full Text] [Related]

  • 13. Temocaprilat, a novel angiotensin-converting enzyme inhibitor, is excreted in bile via an ATP-dependent active transporter (cMOAT) that is deficient in Eisai hyperbilirubinemic mutant rats (EHBR).
    Ishizuka H, Konno K, Naganuma H, Sasahara K, Kawahara Y, Niinuma K, Suzuki H, Sugiyama Y.
    J Pharmacol Exp Ther; 1997 Mar 03; 280(3):1304-11. PubMed ID: 9067317
    [Abstract] [Full Text] [Related]

  • 14. Evaluation of the endothelin receptor antagonists ambrisentan, darusentan, bosentan, and sitaxsentan as substrates and inhibitors of hepatobiliary transporters in sandwich-cultured human hepatocytes.
    Hartman JC, Brouwer K, Mandagere A, Melvin L, Gorczynski R.
    Can J Physiol Pharmacol; 2010 Jun 03; 88(6):682-91. PubMed ID: 20628435
    [Abstract] [Full Text] [Related]

  • 15. Use of cryopreserved human hepatocytes in sandwich culture to measure hepatobiliary transport.
    Bi YA, Kazolias D, Duignan DB.
    Drug Metab Dispos; 2006 Sep 03; 34(9):1658-65. PubMed ID: 16782767
    [Abstract] [Full Text] [Related]

  • 16. Pharmacokinetic study of the hepatobiliary transport of indomethacin.
    Kouzuki H, Suzuki H, Sugiyama Y.
    Pharm Res; 2000 Apr 03; 17(4):432-8. PubMed ID: 10870987
    [Abstract] [Full Text] [Related]

  • 17. Confocal imaging with a fluorescent bile acid analogue closely mimicking hepatic taurocholate disposition.
    De Bruyn T, Sempels W, Snoeys J, Holmstock N, Chatterjee S, Stieger B, Augustijns P, Hofkens J, Mizuno H, Annaert P.
    J Pharm Sci; 2014 Jun 03; 103(6):1872-81. PubMed ID: 24652646
    [Abstract] [Full Text] [Related]

  • 18. Carrier-mediated hepatic uptake of the cationic cyclopeptide, octreotide, in rats. Comparison between in vivo and in vitro.
    Yamada T, Niinuma K, Lemaire M, Terasaki T, Sugiyama Y.
    Drug Metab Dispos; 1997 May 03; 25(5):536-43. PubMed ID: 9152591
    [Abstract] [Full Text] [Related]

  • 19. In vitro investigation of the hepatobiliary disposition mechanisms of the antifungal agent micafungin in humans and rats.
    Yanni SB, Augustijns PF, Benjamin DK, Brouwer KL, Thakker DR, Annaert PP.
    Drug Metab Dispos; 2010 Oct 03; 38(10):1848-56. PubMed ID: 20606004
    [Abstract] [Full Text] [Related]

  • 20. In vivo biliary clearance should be predicted by intrinsic biliary clearance in sandwich-cultured hepatocytes.
    Nakakariya M, Ono M, Amano N, Moriwaki T, Maeda K, Sugiyama Y.
    Drug Metab Dispos; 2012 Mar 03; 40(3):602-9. PubMed ID: 22190695
    [Abstract] [Full Text] [Related]

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