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166 related items for PubMed ID: 20538722
21. Hepatobiliary transport of a nonpeptidic endothelin antagonist, (+)-(5S,6R,7R)-2-butyl-7-[2((2S)-2-carboxypropyl)-4-methoxyphenyl]-5-(3,4-methylenedioxyphenyl) cyclopentenol[1,2-b]pyridine-6-carboxylic acid: uptake by isolated rat hepatocytes and canalicular membrane vesicles. Kobayashi N, Tani T, Hisaka A, Hara K, Yasumori T. Pharm Res; 2003 Jan; 20(1):89-95. PubMed ID: 12608541 [Abstract] [Full Text] [Related]
24. Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump. Mita S, Suzuki H, Akita H, Stieger B, Meier PJ, Hofmann AF, Sugiyama Y. Am J Physiol Gastrointest Liver Physiol; 2005 Jan; 288(1):G159-67. PubMed ID: 15297262 [Abstract] [Full Text] [Related]
25. Hepatic transport of PKI166, an epidermal growth factor receptor kinase inhibitor of the pyrrolo-pyrimidine class, and its main metabolite, ACU154. Takada T, Weiss HM, Kretz O, Gross G, Sugiyama Y. Drug Metab Dispos; 2004 Nov; 32(11):1272-8. PubMed ID: 15280219 [Abstract] [Full Text] [Related]
27. Quantitative time-lapse imaging-based analysis of drug-drug interaction mediated by hepatobiliary transporter, multidrug resistance-associated protein 2, in sandwich-cultured rat hepatocytes. Nakanishi T, Shibue Y, Fukuyama Y, Yoshida K, Fukuda H, Shirasaka Y, Tamai I. Drug Metab Dispos; 2011 Jun; 39(6):984-91. PubMed ID: 21415249 [Abstract] [Full Text] [Related]
28. Transport mechanisms of hepatic uptake and bile excretion in clinical hepatobiliary scintigraphy with 99mTc-N-pyridoxyl-5-methyltryptophan. Kobayashi M, Nakanishi T, Nishi K, Higaki Y, Okudaira H, Ono M, Tsujiuchi T, Mizutani A, Nishii R, Tamai I, Arano Y, Kawai K. Nucl Med Biol; 2014 Apr; 41(4):338-42. PubMed ID: 24607436 [Abstract] [Full Text] [Related]
29. Saturation of multidrug-resistant protein 2 (mrp2/abcc2)-mediated hepatobiliary secretion: nonlinear pharmacokinetics of a heterocyclic compound in rats after intravenous bolus administration. Hu Y, Sampson KE, Heyde BR, Mandrell KM, Li N, Zutshi A, Lai Y. Drug Metab Dispos; 2009 Apr; 37(4):841-6. PubMed ID: 19139164 [Abstract] [Full Text] [Related]
31. The hepatobiliary disposition of timosaponin b2 is highly dependent on influx/efflux transporters but not metabolism. Sheng J, Tian X, Xu G, Wu Z, Chen C, Wang L, Pan L, Huang C, Pan G. Drug Metab Dispos; 2015 Jan; 43(1):63-72. PubMed ID: 25336752 [Abstract] [Full Text] [Related]
32. Involvement of multiple transporters in the hepatobiliary transport of rosuvastatin. Kitamura S, Maeda K, Wang Y, Sugiyama Y. Drug Metab Dispos; 2008 Oct; 36(10):2014-23. PubMed ID: 18617601 [Abstract] [Full Text] [Related]
33. Carrier-mediated hepatobiliary transport of a novel antifolate, N-[4-[(2,4-dianninopteridine-6-yl)methyl]-3,4-dihydro-2H-1,4-benzothiazin-7-yl]carbonyl-L-homoglutamic acid, in rats. Han YH, Kato Y, Watanabe Y, Terao K, Asoh Y, Sugiyama Y. Drug Metab Dispos; 2001 Apr; 29(4 Pt 1):394-400. PubMed ID: 11259322 [Abstract] [Full Text] [Related]
34. Primary active transport of pravastatin across the liver canalicular membrane in normal and mutant Eisai hyperbilirubinaemic rats. Yamazaki M, Kobayashi K, Sugiyama Y. Biopharm Drug Dispos; 1996 Nov; 17(8):645-59. PubMed ID: 8950045 [Abstract] [Full Text] [Related]
35. Down-regulation of organic anion transporter expression in human hepatocytes exposed to the proinflammatory cytokine interleukin 1beta. Le Vee M, Gripon P, Stieger B, Fardel O. Drug Metab Dispos; 2008 Feb; 36(2):217-22. PubMed ID: 17991769 [Abstract] [Full Text] [Related]
36. Primary active transport of pravastatin across the liver canalicular membrane in normal and mutant Eisai hyperbilirubinemic rats. Yamazaki M, Kobayashi K, Sugiyama Y. Biopharm Drug Dispos; 1996 Oct; 17(7):607-21. PubMed ID: 8894118 [Abstract] [Full Text] [Related]
37. Hepatobiliary disposition in primary cultures of dog and monkey hepatocytes. Rose KA, Kostrubsky V, Sahi J. Mol Pharm; 2006 Oct; 3(3):266-74. PubMed ID: 16749858 [Abstract] [Full Text] [Related]
38. Pharmacokinetic analysis of ramatroban using a recirculatory model with enterohepatic circulation by measuring portal and systemic blood concentration difference in Sprague-Dawley and Eisai hyperbilirubinemic rats. Moriwaki T, Yasui H, Yamamoto A. Pharm Res; 2004 Jun; 21(6):1055-64. PubMed ID: 15212172 [Abstract] [Full Text] [Related]
39. An experimental approach to evaluate the impact of impaired transport function on hepatobiliary drug disposition using Mrp2-deficient TR- rat sandwich-cultured hepatocytes in combination with Bcrp knockdown. Yang K, Pfeifer ND, Hardwick RN, Yue W, Stewart PW, Brouwer KL. Mol Pharm; 2014 Mar 03; 11(3):766-75. PubMed ID: 24410402 [Abstract] [Full Text] [Related]
40. Hepatic basolateral efflux contributes significantly to rosuvastatin disposition II: characterization of hepatic elimination by basolateral, biliary, and metabolic clearance pathways in rat isolated perfused liver. Pfeifer ND, Bridges AS, Ferslew BC, Hardwick RN, Brouwer KL. J Pharmacol Exp Ther; 2013 Dec 03; 347(3):737-45. PubMed ID: 24080682 [Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]