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208 related items for PubMed ID: 20542099

  • 1. Genotoxic polycyclic aromatic hydrocarbons fail to induce the p53-dependent DNA damage response, apoptosis or cell-cycle arrest in human prostate carcinoma LNCaP cells.
    Hrubá E, Trilecová L, Marvanová S, Krcmár P, Vykopalová L, Milcová A, Líbalová H, Topinka J, Starsíchová A, Soucek K, Vondrácek J, Machala M.
    Toxicol Lett; 2010 Sep 01; 197(3):227-35. PubMed ID: 20542099
    [Abstract] [Full Text] [Related]

  • 2. DNA adducts formation and induction of apoptosis in rat liver epithelial 'stem-like' cells exposed to carcinogenic polycyclic aromatic hydrocarbons.
    Topinka J, Marvanová S, Vondrácek J, Sevastyanova O, Nováková Z, Krcmár P, Pencíková K, Machala M.
    Mutat Res; 2008 Feb 01; 638(1-2):122-32. PubMed ID: 17961608
    [Abstract] [Full Text] [Related]

  • 3. Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism.
    Wohak LE, Krais AM, Kucab JE, Stertmann J, Øvrebø S, Seidel A, Phillips DH, Arlt VM.
    Arch Toxicol; 2016 Feb 01; 90(2):291-304. PubMed ID: 25398514
    [Abstract] [Full Text] [Related]

  • 4. Deregulation of cell proliferation by polycyclic aromatic hydrocarbons in human breast carcinoma MCF-7 cells reflects both genotoxic and nongenotoxic events.
    Plísková M, Vondrácek J, Vojtesek B, Kozubík A, Machala M.
    Toxicol Sci; 2005 Feb 01; 83(2):246-56. PubMed ID: 15548639
    [Abstract] [Full Text] [Related]

  • 5. Toxic effects of methylated benzo[a]pyrenes in rat liver stem-like cells.
    Trilecová L, Krčková S, Marvanová S, Pĕnčíková K, Krčmář P, Neča J, Hulinková P, Pálková L, Ciganek M, Milcová A, Topinka J, Vondráček J, Machala M.
    Chem Res Toxicol; 2011 Jun 20; 24(6):866-76. PubMed ID: 21604763
    [Abstract] [Full Text] [Related]

  • 6. Role and interaction of p53, BAX and the stress-activated protein kinases p38 and JNK in benzo(a)pyrene-diolepoxide induced apoptosis in human colon carcinoma cells.
    Donauer J, Schreck I, Liebel U, Weiss C.
    Arch Toxicol; 2012 Feb 20; 86(2):329-37. PubMed ID: 21983885
    [Abstract] [Full Text] [Related]

  • 7. Estrogenic activity of environmental polycyclic aromatic hydrocarbons in uterus of immature Wistar rats.
    Kummer V, Masková J, Zralý Z, Neca J, Simecková P, Vondrácek J, Machala M.
    Toxicol Lett; 2008 Aug 28; 180(3):212-21. PubMed ID: 18634860
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of β-catenin signalling promotes DNA damage elicited by benzo[a]pyrene in a model of human colon cancer cells via CYP1 deregulation.
    Kabátková M, Zapletal O, Tylichová Z, Neča J, Machala M, Milcová A, Topinka J, Kozubík A, Vondráček J.
    Mutagenesis; 2015 Jul 28; 30(4):565-76. PubMed ID: 25805023
    [Abstract] [Full Text] [Related]

  • 9. Benzo[a]pyrene-induced DNA damage and p53 modulation in human hepatoma HepG2 cells for the identification of potential biomarkers for PAH monitoring and risk assessment.
    Park SY, Lee SM, Ye SK, Yoon SH, Chung MH, Choi J.
    Toxicol Lett; 2006 Nov 01; 167(1):27-33. PubMed ID: 17029827
    [Abstract] [Full Text] [Related]

  • 10. Polycyclic aromatic hydrocarbons in binary mixtures modulate the efficiency of benzo[a]pyrene to form DNA adducts in human cells.
    Tarantini A, Maître A, Lefèbvre E, Marques M, Rajhi A, Douki T.
    Toxicology; 2011 Jan 11; 279(1-3):36-44. PubMed ID: 20849910
    [Abstract] [Full Text] [Related]

  • 11. The aryl hydrocarbon receptor-dependent deregulation of cell cycle control induced by polycyclic aromatic hydrocarbons in rat liver epithelial cells.
    Andrysík Z, Vondrácek J, Machala M, Krcmár P, Svihálková-Sindlerová L, Kranz A, Weiss C, Faust D, Kozubík A, Dietrich C.
    Mutat Res; 2007 Feb 03; 615(1-2):87-97. PubMed ID: 17141280
    [Abstract] [Full Text] [Related]

  • 12. Gene expression changes in human prostate carcinoma cells exposed to genotoxic and nongenotoxic aryl hydrocarbon receptor ligands.
    Hrubá E, Vondráček J, Líbalová H, Topinka J, Bryja V, Souček K, Machala M.
    Toxicol Lett; 2011 Oct 10; 206(2):178-88. PubMed ID: 21802500
    [Abstract] [Full Text] [Related]

  • 13. Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: chemical-, cytochrome P450 isoform-, and cell-specific differences.
    Iwanari M, Nakajima M, Kizu R, Hayakawa K, Yokoi T.
    Arch Toxicol; 2002 Jun 10; 76(5-6):287-98. PubMed ID: 12107646
    [Abstract] [Full Text] [Related]

  • 14. The role of aryl hydrocarbon receptor in regulation of enzymes involved in metabolic activation of polycyclic aromatic hydrocarbons in a model of rat liver progenitor cells.
    Vondrácek J, Krcmár P, Procházková J, Trilecová L, Gavelová M, Skálová L, Szotáková B, Buncek M, Radilová H, Kozubík A, Machala M.
    Chem Biol Interact; 2009 Jul 15; 180(2):226-37. PubMed ID: 19497421
    [Abstract] [Full Text] [Related]

  • 15. Effects of nitrated-polycyclic aromatic hydrocarbons and diesel exhaust particle extracts on cell signalling related to apoptosis: possible implications for their mutagenic and carcinogenic effects.
    Landvik NE, Gorria M, Arlt VM, Asare N, Solhaug A, Lagadic-Gossmann D, Holme JA.
    Toxicology; 2007 Mar 07; 231(2-3):159-74. PubMed ID: 17240030
    [Abstract] [Full Text] [Related]

  • 16. Induction of proliferative and mutagenic activity by benzo(a)pyrene in PC-3 cells via JAK2/STAT3 pathway.
    Gao M, Li H, Dang F, Chen L, Liu X, Gao J.
    Mutat Res; 2020 Mar 07; 821():111720. PubMed ID: 32841893
    [Abstract] [Full Text] [Related]

  • 17. Activation of ERK1/2 and p38 kinases by polycyclic aromatic hydrocarbons in rat liver epithelial cells is associated with induction of apoptosis.
    Andrysík Z, Machala M, Chramostová K, Hofmanová J, Kozubík A, Vondrácek J.
    Toxicol Appl Pharmacol; 2006 Mar 15; 211(3):198-208. PubMed ID: 16005925
    [Abstract] [Full Text] [Related]

  • 18. Benzo[a]pyrene and tumor necrosis factor-α coordinately increase genotoxic damage and the production of proinflammatory mediators in alveolar epithelial type II cells.
    Umannová L, Machala M, Topinka J, Schmuczerová J, Krčmář P, Neča J, Šujanová K, Kozubík A, Vondráček J.
    Toxicol Lett; 2011 Oct 10; 206(2):121-9. PubMed ID: 21745554
    [Abstract] [Full Text] [Related]

  • 19. Tumor necrosis factor-alpha potentiates genotoxic effects of benzo[a]pyrene in rat liver epithelial cells through upregulation of cytochrome P450 1B1 expression.
    Umannová L, Machala M, Topinka J, Nováková Z, Milcová A, Kozubík A, Vondrácek J.
    Mutat Res; 2008 Apr 02; 640(1-2):162-9. PubMed ID: 18336843
    [Abstract] [Full Text] [Related]

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