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399 related items for PubMed ID: 20543108

  • 1. The exocytosis of lytic granules is impaired in Vti1b- or Vamp8-deficient CTL leading to a reduced cytotoxic activity following antigen-specific activation.
    Dressel R, Elsner L, Novota P, Kanwar N, Fischer von Mollard G.
    J Immunol; 2010 Jul 15; 185(2):1005-14. PubMed ID: 20543108
    [Abstract] [Full Text] [Related]

  • 2. A role for endobrevin/VAMP8 in CTL lytic granule exocytosis.
    Loo LS, Hwang LA, Ong YM, Tay HS, Wang CC, Hong W.
    Eur J Immunol; 2009 Dec 15; 39(12):3520-8. PubMed ID: 19830729
    [Abstract] [Full Text] [Related]

  • 3. The duration of TCR/pMHC interactions regulates CTL effector function and tumor-killing capacity.
    Riquelme E, Carreño LJ, González PA, Kalergis AM.
    Eur J Immunol; 2009 Aug 15; 39(8):2259-69. PubMed ID: 19637198
    [Abstract] [Full Text] [Related]

  • 4. Activation of primary T lymphocytes results in lysosome development and polarized granule exocytosis in CD4+ and CD8+ subsets, whereas expression of lytic molecules confers cytotoxicity to CD8+ T cells.
    Shen DT, Ma JS, Mather J, Vukmanovic S, Radoja S.
    J Leukoc Biol; 2006 Oct 15; 80(4):827-37. PubMed ID: 16891618
    [Abstract] [Full Text] [Related]

  • 5. The requirements for triggering of lysis by cytolytic T lymphocyte clones. II. Cyclosporin A inhibits TCR-mediated exocytosis by only selectively inhibits TCR-mediated lytic activity by cloned CTL.
    Lancki DW, Kaper BP, Fitch FW.
    J Immunol; 1989 Jan 15; 142(2):416-24. PubMed ID: 2492047
    [Abstract] [Full Text] [Related]

  • 6. An anergic cytotoxic T lymphocyte clone exhibits granule exocytosis-mediated cytotoxicity.
    Kuwano K, Akashi A, Arai S.
    Cell Immunol; 1998 May 01; 185(2):114-22. PubMed ID: 9636689
    [Abstract] [Full Text] [Related]

  • 7. Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells.
    Sander LE, Frank SP, Bolat S, Blank U, Galli T, Bigalke H, Bischoff SC, Lorentz A.
    Eur J Immunol; 2008 Mar 01; 38(3):855-63. PubMed ID: 18253931
    [Abstract] [Full Text] [Related]

  • 8. Modulation of cytolytic T lymphocyte functions by an inhibitor of serine/threonine phosphatase, okadaic acid. Enhancement of cytolytic T lymphocyte-mediated cytotoxicity.
    Taffs RE, Redegeld FA, Sitkovsky MV.
    J Immunol; 1991 Jul 15; 147(2):722-8. PubMed ID: 1649222
    [Abstract] [Full Text] [Related]

  • 9. Defective CD8+ T cell activation and cytolytic function in the absence of LFA-1 cannot be restored by increased TCR signaling.
    Shier P, Ngo K, Fung-Leung WP.
    J Immunol; 1999 Nov 01; 163(9):4826-32. PubMed ID: 10528183
    [Abstract] [Full Text] [Related]

  • 10. Highly lytic in vivo primed cytolytic T lymphocytes devoid of lytic granules and BLT-esterase activity acquire these constituents in the presence of T cell growth factors upon blast transformation in vitro.
    Berke G, Rosen D.
    J Immunol; 1988 Sep 01; 141(5):1429-36. PubMed ID: 3261748
    [Abstract] [Full Text] [Related]

  • 11. Thymic alterations in mice deficient for the SNARE protein VAMP8/endobrevin.
    Kanwar N, Fayyazi A, Backofen B, Nitsche M, Dressel R, von Mollard GF.
    Cell Tissue Res; 2008 Nov 01; 334(2):227-42. PubMed ID: 18923845
    [Abstract] [Full Text] [Related]

  • 12. Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway.
    Isaaz S, Baetz K, Olsen K, Podack E, Griffiths GM.
    Eur J Immunol; 1995 Apr 01; 25(4):1071-9. PubMed ID: 7737276
    [Abstract] [Full Text] [Related]

  • 13. Small-interfering RNA-mediated identification and regulation of the ternary SNARE complex mediating RBL-2H3 mast cell degranulation.
    Woska JR, Gillespie ME.
    Scand J Immunol; 2011 Jan 01; 73(1):8-17. PubMed ID: 21128998
    [Abstract] [Full Text] [Related]

  • 14. Active CD4+ helper T cells directly stimulate CD8+ cytotoxic T lymphocyte responses in wild-type and MHC II gene knockout C57BL/6 mice and transgenic RIP-mOVA mice expressing islet beta-cell ovalbumin antigen leading to diabetes.
    Ye Z, Ahmed KA, Hao S, Zhang X, Xie Y, Munegowda MA, Meng Q, Chibbar R, Xiang J.
    Autoimmunity; 2008 Nov 01; 41(7):501-11. PubMed ID: 18855194
    [Abstract] [Full Text] [Related]

  • 15. Poxvirus-encoded serpins do not prevent cytolytic T cell-mediated recovery from primary infections.
    Müllbacher A, Wallich R, Moyer RW, Simon MM.
    J Immunol; 1999 Jun 15; 162(12):7315-21. PubMed ID: 10358181
    [Abstract] [Full Text] [Related]

  • 16. Vaccination with dendritic cells pulsed in vitro with tumor antigen conjugated to cholera toxin efficiently induces specific tumoricidal CD8+ cytotoxic lymphocytes dependent on cyclic AMP activation of dendritic cells.
    Sun JB, Eriksson K, Li BL, Lindblad M, Azem J, Holmgren J.
    Clin Immunol; 2004 Jul 15; 112(1):35-44. PubMed ID: 15207780
    [Abstract] [Full Text] [Related]

  • 17. Exocytosis of cytolytic granules may not be required for target cell lysis by cytotoxic T-lymphocytes.
    Trenn G, Takayama H, Sitkovsky MV.
    Nature; 2004 Jul 15; 330(6143):72-4. PubMed ID: 3118213
    [Abstract] [Full Text] [Related]

  • 18. Cellular mechanisms of lymphocyte-mediated lysis of tumor cells.
    Arancia G, Malorni W, Donelli G.
    Ann Ist Super Sanita; 1990 Jul 15; 26(3-4):369-84. PubMed ID: 2151107
    [Abstract] [Full Text] [Related]

  • 19. Combinational soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins VAMP8 and Vti1b mediate fusion of antimicrobial and canonical autophagosomes with lysosomes.
    Furuta N, Fujita N, Noda T, Yoshimori T, Amano A.
    Mol Biol Cell; 2010 Mar 15; 21(6):1001-10. PubMed ID: 20089838
    [Abstract] [Full Text] [Related]

  • 20. Concanamycin A, a powerful tool for characterization and estimation of contribution of perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity.
    Kataoka T, Shinohara N, Takayama H, Takaku K, Kondo S, Yonehara S, Nagai K.
    J Immunol; 1996 May 15; 156(10):3678-86. PubMed ID: 8621902
    [Abstract] [Full Text] [Related]

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