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244 related items for PubMed ID: 20546728

  • 1. Polyglutamine-expanded ataxin-7 upregulates Bax expression by activating p53 in cerebellar and inferior olivary neurons.
    Wang HL, Chou AH, Lin AC, Chen SY, Weng YH, Yeh TH.
    Exp Neurol; 2010 Aug; 224(2):486-94. PubMed ID: 20546728
    [Abstract] [Full Text] [Related]

  • 2. p53 activation mediates polyglutamine-expanded ataxin-3 upregulation of Bax expression in cerebellar and pontine nuclei neurons.
    Chou AH, Lin AC, Hong KY, Hu SH, Chen YL, Chen JY, Wang HL.
    Neurochem Int; 2011 Feb; 58(2):145-52. PubMed ID: 21092747
    [Abstract] [Full Text] [Related]

  • 3. Polyglutamine-expanded ataxin-7 causes cerebellar dysfunction by inducing transcriptional dysregulation.
    Chou AH, Chen CY, Chen SY, Chen WJ, Chen YL, Weng YS, Wang HL.
    Neurochem Int; 2010 Jan; 56(2):329-39. PubMed ID: 19909779
    [Abstract] [Full Text] [Related]

  • 4. Polyglutamine-expanded ataxin-7 activates mitochondrial apoptotic pathway of cerebellar neurons by upregulating Bax and downregulating Bcl-x(L).
    Wang HL, Yeh TH, Chou AH, Kuo YL, Luo LJ, He CY, Huang PC, Li AH.
    Cell Signal; 2006 Apr; 18(4):541-52. PubMed ID: 15964171
    [Abstract] [Full Text] [Related]

  • 5. Polyglutamine-expanded ataxin-7 decreases nuclear translocation of NF-kappaB p65 and impairs NF-kappaB activity by inhibiting proteasome activity of cerebellar neurons.
    Wang HL, He CY, Chou AH, Yeh TH, Chen YL, Li AH.
    Cell Signal; 2007 Mar; 19(3):573-81. PubMed ID: 17005371
    [Abstract] [Full Text] [Related]

  • 6. Polyglutamine-expanded ataxin-3 activates mitochondrial apoptotic pathway by upregulating Bax and downregulating Bcl-xL.
    Chou AH, Yeh TH, Kuo YL, Kao YC, Jou MJ, Hsu CY, Tsai SR, Kakizuka A, Wang HL.
    Neurobiol Dis; 2006 Feb; 21(2):333-45. PubMed ID: 16112867
    [Abstract] [Full Text] [Related]

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  • 8. p53 transcription-dependent and -independent regulation of cerebellar neural precursor cell apoptosis.
    Geng Y, Akhtar RS, Shacka JJ, Klocke BJ, Zhang J, Chen X, Roth KA.
    J Neuropathol Exp Neurol; 2007 Jan; 66(1):66-74. PubMed ID: 17204938
    [Abstract] [Full Text] [Related]

  • 9. Gamma interferon-inducible protein 10 induces HeLa cell apoptosis through a p53-dependent pathway initiated by suppression of human papillomavirus type 18 E6 and E7 expression.
    Zhang HM, Yuan J, Cheung P, Chau D, Wong BW, McManus BM, Yang D.
    Mol Cell Biol; 2005 Jul; 25(14):6247-58. PubMed ID: 15988033
    [Abstract] [Full Text] [Related]

  • 10. Decreased expression of Hsp27 and Hsp70 in transformed lymphoblastoid cells from patients with spinocerebellar ataxia type 7.
    Tsai HF, Lin SJ, Li C, Hsieh M.
    Biochem Biophys Res Commun; 2005 Sep 09; 334(4):1279-86. PubMed ID: 16039988
    [Abstract] [Full Text] [Related]

  • 11. Partial resistance of ataxin-2-containing olivary and pontine neurons to axotomy-induced degeneration.
    Viscomi MT, Florenzano F, Amadio S, Bernardi G, Molinari M.
    Brain Res Bull; 2005 Aug 15; 66(3):212-21. PubMed ID: 16023918
    [Abstract] [Full Text] [Related]

  • 12. Altered p53 and NOX1 activity cause bioenergetic defects in a SCA7 polyglutamine disease model.
    Ajayi A, Yu X, Wahlo-Svedin C, Tsirigotaki G, Karlström V, Ström AL.
    Biochim Biophys Acta; 2015 Aug 15; 1847(4-5):418-428. PubMed ID: 25647692
    [Abstract] [Full Text] [Related]

  • 13. Interferon β induces clearance of mutant ataxin 7 and improves locomotion in SCA7 knock-in mice.
    Chort A, Alves S, Marinello M, Dufresnois B, Dornbierer JG, Tesson C, Latouche M, Baker DP, Barkats M, El Hachimi KH, Ruberg M, Janer A, Stevanin G, Brice A, Sittler A.
    Brain; 2013 Jun 15; 136(Pt 6):1732-45. PubMed ID: 23518714
    [Abstract] [Full Text] [Related]

  • 14. Polyglutamine-expanded ataxin-3 causes cerebellar dysfunction of SCA3 transgenic mice by inducing transcriptional dysregulation.
    Chou AH, Yeh TH, Ouyang P, Chen YL, Chen SY, Wang HL.
    Neurobiol Dis; 2008 Jul 15; 31(1):89-101. PubMed ID: 18502140
    [Abstract] [Full Text] [Related]

  • 15. H1152 promotes the degradation of polyglutamine-expanded ataxin-3 or ataxin-7 independently of its ROCK-inhibiting effect and ameliorates mutant ataxin-3-induced neurodegeneration in the SCA3 transgenic mouse.
    Wang HL, Hu SH, Chou AH, Wang SS, Weng YH, Yeh TH.
    Neuropharmacology; 2013 Jul 15; 70():1-11. PubMed ID: 23347954
    [Abstract] [Full Text] [Related]

  • 16. Transcriptional alterations and chromatin remodeling in polyglutamine diseases.
    Helmlinger D, Tora L, Devys D.
    Trends Genet; 2006 Oct 15; 22(10):562-70. PubMed ID: 16911843
    [Abstract] [Full Text] [Related]

  • 17. Spinocerebellar ataxia type 7 cerebellar disease requires the coordinated action of mutant ataxin-7 in neurons and glia, and displays non-cell-autonomous bergmann glia degeneration.
    Furrer SA, Mohanachandran MS, Waldherr SM, Chang C, Damian VA, Sopher BL, Garden GA, La Spada AR.
    J Neurosci; 2011 Nov 09; 31(45):16269-78. PubMed ID: 22072678
    [Abstract] [Full Text] [Related]

  • 18. T1-11 and JMF1907 ameliorate polyglutamine-expanded ataxin-3-induced neurodegeneration, transcriptional dysregulation and ataxic symptom in the SCA3 transgenic mouse.
    Chou AH, Chen YL, Chiu CC, Yuan SJ, Weng YH, Yeh TH, Lin YL, Fang JM, Wang HL.
    Neuropharmacology; 2015 Dec 09; 99():308-17. PubMed ID: 26254860
    [Abstract] [Full Text] [Related]

  • 19. Neuronal dysfunction in a polyglutamine disease model occurs in the absence of ubiquitin-proteasome system impairment and inversely correlates with the degree of nuclear inclusion formation.
    Bowman AB, Yoo SY, Dantuma NP, Zoghbi HY.
    Hum Mol Genet; 2005 Mar 01; 14(5):679-91. PubMed ID: 15661755
    [Abstract] [Full Text] [Related]

  • 20. Reduction of Purkinje cell pathology in SCA1 transgenic mice by p53 deletion.
    Shahbazian MD, Orr HT, Zoghbi HY.
    Neurobiol Dis; 2001 Dec 01; 8(6):974-81. PubMed ID: 11741393
    [Abstract] [Full Text] [Related]

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