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310 related items for PubMed ID: 20566639

  • 1. Cystathionine gamma-Lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury.
    Ishii I, Akahoshi N, Yamada H, Nakano S, Izumi T, Suematsu M.
    J Biol Chem; 2010 Aug 20; 285(34):26358-68. PubMed ID: 20566639
    [Abstract] [Full Text] [Related]

  • 2. Neutral aminoaciduria in cystathionine β-synthase-deficient mice; an animal model of homocystinuria.
    Akahoshi N, Kamata S, Kubota M, Hishiki T, Nagahata Y, Matsuura T, Yamazaki C, Yoshida Y, Yamada H, Ishizaki Y, Suematsu M, Kasahara T, Ishii I.
    Am J Physiol Renal Physiol; 2014 Jun 15; 306(12):F1462-76. PubMed ID: 24761004
    [Abstract] [Full Text] [Related]

  • 3. Methionine excess in diet induces acute lethal hepatitis in mice lacking cystathionine γ-lyase, an animal model of cystathioninuria.
    Yamada H, Akahoshi N, Kamata S, Hagiya Y, Hishiki T, Nagahata Y, Matsuura T, Takano N, Mori M, Ishizaki Y, Izumi T, Kumagai Y, Kasahara T, Suematsu M, Ishii I.
    Free Radic Biol Med; 2012 May 01; 52(9):1716-26. PubMed ID: 22387178
    [Abstract] [Full Text] [Related]

  • 4. Preeclampsia-Like Features and Partial Lactation Failure in Mice Lacking Cystathionine γ-Lyase-An Animal Model of Cystathioninuria.
    Akahoshi N, Handa H, Takemoto R, Kamata S, Yoshida M, Onaka T, Ishii I.
    Int J Mol Sci; 2019 Jul 17; 20(14):. PubMed ID: 31319489
    [Abstract] [Full Text] [Related]

  • 5. Abnormal Amino Acid Profiles of Blood and Cerebrospinal Fluid from Cystathionine β-Synthase-Deficient Mice, an Animal Model of Homocystinuria.
    Akahoshi N, Yokoyama A, Nagata T, Miura A, Kamata S, Ishii I.
    Biol Pharm Bull; 2019 Jul 17; 42(6):1054-1057. PubMed ID: 31155583
    [Abstract] [Full Text] [Related]

  • 6. Hyperhomocysteinemia abrogates fasting-induced cardioprotection against ischemia/reperfusion by limiting bioavailability of hydrogen sulfide anions.
    Nakano S, Ishii I, Shinmura K, Tamaki K, Hishiki T, Akahoshi N, Ida T, Nakanishi T, Kamata S, Kumagai Y, Akaike T, Fukuda K, Sano M, Suematsu M.
    J Mol Med (Berl); 2015 Aug 17; 93(8):879-89. PubMed ID: 25740079
    [Abstract] [Full Text] [Related]

  • 7. Hemizygosity of transsulfuration genes confers increased vulnerability against acetaminophen-induced hepatotoxicity in mice.
    Hagiya Y, Kamata S, Mitsuoka S, Okada N, Yoshida S, Yamamoto J, Ohkubo R, Abiko Y, Yamada H, Akahoshi N, Kasahara T, Kumagai Y, Ishii I.
    Toxicol Appl Pharmacol; 2015 Jan 15; 282(2):195-206. PubMed ID: 25499718
    [Abstract] [Full Text] [Related]

  • 8. Homocysteine Hypothesis on the Impaired Peripheral but Not Central Nervous System Oxytocin Responses in Cystathionine γ-Lyase-Deficient Dam Mice.
    Akahoshi N, Kamichatani W, Ishii I.
    Biol Pharm Bull; 2020 Jan 15; 43(11):1810-1813. PubMed ID: 33132327
    [Abstract] [Full Text] [Related]

  • 9. Skeletal muscle cystathionine γ-lyase deficiency promotes obesity and insulin resistance and results in hyperglycemia and skeletal muscle injury upon HFD in mice.
    Lu J, Tang Z, Xu M, Lu J, Wang F, Ni X, Wang C, Yu B.
    Redox Rep; 2024 Dec 15; 29(1):2347139. PubMed ID: 38718286
    [Abstract] [Full Text] [Related]

  • 10. [Cystathionine γ-lyase].
    Jurkowska H, Kaczor-Kamińska M, Bronowicka-Adamska P, Wróbel M.
    Postepy Hig Med Dosw (Online); 2014 Jan 15; 68():1-9. PubMed ID: 24491890
    [Abstract] [Full Text] [Related]

  • 11. Relative contributions of cystathionine beta-synthase and gamma-cystathionase to H2S biogenesis via alternative trans-sulfuration reactions.
    Singh S, Padovani D, Leslie RA, Chiku T, Banerjee R.
    J Biol Chem; 2009 Aug 14; 284(33):22457-22466. PubMed ID: 19531479
    [Abstract] [Full Text] [Related]

  • 12. Increased Urinary 3-Mercaptolactate Excretion and Enhanced Passive Systemic Anaphylaxis in Mice Lacking Mercaptopyruvate Sulfurtransferase, a Model of Mercaptolactate-Cysteine Disulfiduria.
    Akahoshi N, Minakawa T, Miyashita M, Sugiyama U, Saito C, Takemoto R, Honda A, Kamichatani W, Kamata S, Anan Y, Ishii I.
    Int J Mol Sci; 2020 Jan 27; 21(3):. PubMed ID: 32012740
    [Abstract] [Full Text] [Related]

  • 13. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH).
    Wang J, Hegele RA.
    Hum Genet; 2003 Apr 27; 112(4):404-8. PubMed ID: 12574942
    [Abstract] [Full Text] [Related]

  • 14. Hydrogen sulfide lowers hyperhomocysteinemia dependent on cystathionine γ lyase S-sulfhydration in ApoE-knockout atherosclerotic mice.
    Fan J, Zheng F, Li S, Cui C, Jiang S, Zhang J, Cai J, Cui Q, Yang J, Tang X, Xu G, Geng B.
    Br J Pharmacol; 2019 Sep 27; 176(17):3180-3192. PubMed ID: 31140595
    [Abstract] [Full Text] [Related]

  • 15. Genetic background conversion ameliorates semi-lethality and permits behavioral analyses in cystathionine beta-synthase-deficient mice, an animal model for hyperhomocysteinemia.
    Akahoshi N, Kobayashi C, Ishizaki Y, Izumi T, Himi T, Suematsu M, Ishii I.
    Hum Mol Genet; 2008 Jul 01; 17(13):1994-2005. PubMed ID: 18364386
    [Abstract] [Full Text] [Related]

  • 16. Cysteinemia, rather than homocysteinemia, is associated with plasma apolipoprotein A-I levels in hyperhomocysteinemia: lipid metabolism in cystathionine beta-synthase deficiency.
    Nuño-Ayala M, Guillén N, Navarro MA, Lou-Bonafonte JM, Arnal C, Gascón S, Barranquero C, Godino J, Royo-Cañas M, Sarría AJ, Guzmán MA, Hernandez E, Bregante MA, García-Gimeno MA, Osada J.
    Atherosclerosis; 2010 Sep 01; 212(1):268-73. PubMed ID: 20537649
    [Abstract] [Full Text] [Related]

  • 17. The H2S-generating enzymes cystathionine β-synthase and cystathionine γ-lyase play a role in vascular development during normal lung alveolarization.
    Madurga A, Golec A, Pozarska A, Ishii I, Mižíková I, Nardiello C, Vadász I, Herold S, Mayer K, Reichenberger F, Fehrenbach H, Seeger W, Morty RE.
    Am J Physiol Lung Cell Mol Physiol; 2015 Oct 01; 309(7):L710-24. PubMed ID: 26232299
    [Abstract] [Full Text] [Related]

  • 18. E2β stimulates ovine uterine artery endothelial cell H2S production in vitro by estrogen receptor-dependent upregulation of cystathionine β-synthase and cystathionine γ-lyase expression†.
    Lechuga TJ, Qi QR, Kim T, Magness RR, Chen DB.
    Biol Reprod; 2019 Feb 01; 100(2):514-522. PubMed ID: 30277497
    [Abstract] [Full Text] [Related]

  • 19. A role for glutamate-333 of Saccharomyces cerevisiae cystathionine γ-lyase as a determinant of specificity.
    Hopwood EM, Ahmed D, Aitken SM.
    Biochim Biophys Acta; 2014 Feb 01; 1844(2):465-72. PubMed ID: 24291053
    [Abstract] [Full Text] [Related]

  • 20. Hydrogen sulfide generation in mammals: the molecular biology of cystathionine-β- synthase (CBS) and cystathionine-γ-lyase (CSE).
    Renga B.
    Inflamm Allergy Drug Targets; 2011 Apr 01; 10(2):85-91. PubMed ID: 21275900
    [Abstract] [Full Text] [Related]

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