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Journal Abstract Search

273 related items for PubMed ID: 20566695

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  • 3. Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2.
    Rhodes SP, Otten JN, Hingorani GP, Hartley DP, Franklin RB.
    J Pharmacol Toxicol Methods; 2011; 63(3):223-6. PubMed ID: 21111054
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  • 4. Calcium channel modulators of the dihydropyridine family are human pregnane X receptor activators and inducers of CYP3A, CYP2B, and CYP2C in human hepatocytes.
    Drocourt L, Pascussi JM, Assenat E, Fabre JM, Maurel P, Vilarem MJ.
    Drug Metab Dispos; 2001 Oct; 29(10):1325-31. PubMed ID: 11560876
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  • 7. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
    Casabar RC, Das PC, Dekrey GK, Gardiner CS, Cao Y, Rose RL, Wallace AD.
    Toxicol Appl Pharmacol; 2010 Jun 15; 245(3):335-43. PubMed ID: 20361990
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  • 8. Investigation of drug-drug interactions caused by human pregnane X receptor-mediated induction of CYP3A4 and CYP2C subfamilies in chimeric mice with a humanized liver.
    Hasegawa M, Tahara H, Inoue R, Kakuni M, Tateno C, Ushiki J.
    Drug Metab Dispos; 2012 Mar 15; 40(3):474-80. PubMed ID: 22126990
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  • 10. Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three-Dimensional Spheroid Cultures of Primary Human Hepatocytes.
    Hendriks DFG, Vorrink SU, Smutny T, Sim SC, Nordling Å, Ullah S, Kumondai M, Jones BC, Johansson I, Andersson TB, Lauschke VM, Ingelman-Sundberg M.
    Clin Pharmacol Ther; 2020 Oct 15; 108(4):844-855. PubMed ID: 32320483
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  • 13. Benzodiazepines medazepam and midazolam are activators of pregnane X receptor and weak inducers of CYP3A4: investigation in primary cultures of human hepatocytes and hepatocarcinoma cell lines.
    Vrzal R, Kubesova K, Pavek P, Dvorak Z.
    Toxicol Lett; 2010 Mar 15; 193(2):183-8. PubMed ID: 20080160
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  • 14. Induction of CYP3A4 and MDR1 gene expression by baicalin, baicalein, chlorogenic acid, and ginsenoside Rf through constitutive androstane receptor- and pregnane X receptor-mediated pathways.
    Li Y, Wang Q, Yao X, Li Y.
    Eur J Pharmacol; 2010 Aug 25; 640(1-3):46-54. PubMed ID: 20580705
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  • 15. Induction of CYP3A4 by efavirenz in primary human hepatocytes: comparison with rifampin and phenobarbital.
    Hariparsad N, Nallani SC, Sane RS, Buckley DJ, Buckley AR, Desai PB.
    J Clin Pharmacol; 2004 Nov 25; 44(11):1273-81. PubMed ID: 15496645
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  • 18. Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers.
    Faucette SR, Zhang TC, Moore R, Sueyoshi T, Omiecinski CJ, LeCluyse EL, Negishi M, Wang H.
    J Pharmacol Exp Ther; 2007 Jan 25; 320(1):72-80. PubMed ID: 17041008
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  • 20. Evaluation of 23 lots of commercially available cryopreserved hepatocytes for induction assays of human cytochromes P450.
    Yajima K, Uno Y, Murayama N, Uehara S, Shimizu M, Nakamura C, Iwasaki K, Utoh M, Yamazaki H.
    Drug Metab Dispos; 2014 May 25; 42(5):867-71. PubMed ID: 24553381
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