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112 related items for PubMed ID: 20568733

  • 1. Kinetic evidence for the sequential association of insulin binding sites 1 and 2 to the insulin receptor and the influence of receptor isoform.
    Thorsøe KS, Schlein M, Steensgaard DB, Brandt J, Schluckebier G, Naver H.
    Biochemistry; 2010 Jul 27; 49(29):6234-46. PubMed ID: 20568733
    [Abstract] [Full Text] [Related]

  • 2. Ligand-induced activation of the insulin receptor: a multi-step process involving structural changes in both the ligand and the receptor.
    Ward CW, Lawrence MC.
    Bioessays; 2009 Apr 27; 31(4):422-34. PubMed ID: 19274663
    [Abstract] [Full Text] [Related]

  • 3. A thermodynamic study of ligand binding to the first three domains of the human insulin receptor: relationship between the receptor alpha-chain C-terminal peptide and the site 1 insulin mimetic peptides.
    Menting JG, Ward CW, Margetts MB, Lawrence MC.
    Biochemistry; 2009 Jun 16; 48(23):5492-500. PubMed ID: 19459609
    [Abstract] [Full Text] [Related]

  • 4. Insight into the molecular basis for the kinetic differences between the two insulin receptor isoforms.
    Knudsen L, De Meyts P, Kiselyov VV.
    Biochem J; 2011 Dec 15; 440(3):397-403. PubMed ID: 21838706
    [Abstract] [Full Text] [Related]

  • 5. Structural insights into ligand-induced activation of the insulin receptor.
    Ward C, Lawrence M, Streltsov V, Garrett T, McKern N, Lou MZ, Lovrecz G, Adams T.
    Acta Physiol (Oxf); 2008 Jan 15; 192(1):3-9. PubMed ID: 18171424
    [Abstract] [Full Text] [Related]

  • 6. The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: a review.
    Denley A, Wallace JC, Cosgrove LJ, Forbes BE.
    Horm Metab Res; 2003 Jan 15; 35(11-12):778-85. PubMed ID: 14710358
    [Abstract] [Full Text] [Related]

  • 7. Increased levels of insulin and insulin-like growth factor-1 hybrid receptors and decreased glycosylation of the insulin receptor alpha- and beta-subunits in scrapie-infected neuroblastoma N2a cells.
    Nielsen D, Gyllberg H, Ostlund P, Bergman T, Bedecs K.
    Biochem J; 2004 Jun 01; 380(Pt 2):571-9. PubMed ID: 15025560
    [Abstract] [Full Text] [Related]

  • 8. The insulin-binding domain of insulin receptor is encoded by exon 2 and exon 3.
    Yip CC.
    J Cell Biochem; 1992 Jan 01; 48(1):19-25. PubMed ID: 1316357
    [Abstract] [Full Text] [Related]

  • 9. Molecular mechanisms of differential intracellular signaling from the insulin receptor.
    Jensen M, De Meyts P.
    Vitam Horm; 2009 Jan 01; 80():51-75. PubMed ID: 19251034
    [Abstract] [Full Text] [Related]

  • 10. Importance of the solvent-exposed residues of the insulin B chain alpha-helix for receptor binding.
    Glendorf T, Sørensen AR, Nishimura E, Pettersson I, Kjeldsen T.
    Biochemistry; 2008 Apr 22; 47(16):4743-51. PubMed ID: 18376848
    [Abstract] [Full Text] [Related]

  • 11. Re-engineering the target specificity of the insulin receptor by modification of a PTB domain binding site.
    van der Geer P, Wiley S, Pawson T.
    Oncogene; 1999 May 20; 18(20):3071-5. PubMed ID: 10340378
    [Abstract] [Full Text] [Related]

  • 12. Differential endocytosis and signaling dynamics of insulin receptor variants IR-A and IR-B.
    Giudice J, Leskow FC, Arndt-Jovin DJ, Jovin TM, Jares-Erijman EA.
    J Cell Sci; 2011 Mar 01; 124(Pt 5):801-11. PubMed ID: 21303927
    [Abstract] [Full Text] [Related]

  • 13. Insulin receptor activation by IGF-II in breast cancers: evidence for a new autocrine/paracrine mechanism.
    Sciacca L, Costantino A, Pandini G, Mineo R, Frasca F, Scalia P, Sbraccia P, Goldfine ID, Vigneri R, Belfiore A.
    Oncogene; 1999 Apr 15; 18(15):2471-9. PubMed ID: 10229198
    [Abstract] [Full Text] [Related]

  • 14. Direct determination of the insulin-insulin receptor interface using transferred cross-saturation experiments.
    Nakamura T, Takahashi H, Takahashi M, Shimba N, Suzuki E, Shimada I.
    J Med Chem; 2010 Mar 11; 53(5):1917-22. PubMed ID: 20158183
    [Abstract] [Full Text] [Related]

  • 15. [The structural organization of binding determinants in insulin-like growth factor-I (IGF-I) molecule].
    Kolychev AP.
    Zh Evol Biokhim Fiziol; 2010 Mar 11; 46(1):74-94. PubMed ID: 20297673
    [Abstract] [Full Text] [Related]

  • 16. Characterization of a second ligand binding site of the insulin receptor.
    Hao C, Whittaker L, Whittaker J.
    Biochem Biophys Res Commun; 2006 Aug 18; 347(1):334-9. PubMed ID: 16814253
    [Abstract] [Full Text] [Related]

  • 17. Unusual insulin binding to cells expressing an insulin receptor mutated at cysteine 524.
    Bilan PJ, Yip CC.
    Biochem Biophys Res Commun; 1994 Dec 30; 205(3):1891-8. PubMed ID: 7811279
    [Abstract] [Full Text] [Related]

  • 18. Diabetes-associated mutations in human insulin: crystal structure and photo-cross-linking studies of a-chain variant insulin Wakayama.
    Wan ZL, Huang K, Xu B, Hu SQ, Wang S, Chu YC, Katsoyannis PG, Weiss MA.
    Biochemistry; 2005 Apr 05; 44(13):5000-16. PubMed ID: 15794638
    [Abstract] [Full Text] [Related]

  • 19. A structural switch in a mutant insulin exposes key residues for receptor binding.
    Ludvigsen S, Olsen HB, Kaarsholm NC.
    J Mol Biol; 1998 May 29; 279(1):1-7. PubMed ID: 9636695
    [Abstract] [Full Text] [Related]

  • 20. Diabetes-associated mutations in insulin: consecutive residues in the B chain contact distinct domains of the insulin receptor.
    Xu B, Hu SQ, Chu YC, Huang K, Nakagawa SH, Whittaker J, Katsoyannis PG, Weiss MA.
    Biochemistry; 2004 Jul 06; 43(26):8356-72. PubMed ID: 15222748
    [Abstract] [Full Text] [Related]


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